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Pepsin A (Pepsin)

Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
Also Known As:
Pepsin; Pepsin 1; Pepsin 3
Networked: 1084 relevant articles (30 outcomes, 115 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Johnston, Nikki: 19 articles (12/2015 - 12/2004)
2. Dettmar, Peter W: 11 articles (10/2013 - 02/2002)
3. He, Zhaoping: 7 articles (04/2015 - 09/2006)
4. Samuels, Tina L: 6 articles (12/2015 - 11/2009)
5. Soundar, Sam: 6 articles (04/2015 - 09/2006)
6. Sifrim, Daniel: 5 articles (03/2015 - 04/2008)
7. Takeuchi, Koji: 5 articles (01/2014 - 01/2005)
8. Konturek, S J: 5 articles (02/2011 - 01/2000)
9. Goel, R K: 5 articles (04/2009 - 10/2000)
10. O'Reilly, Robert C: 4 articles (04/2015 - 07/2007)

Related Diseases

1. Duodenal Ulcer (Curling's Ulcer)
2. Gastroesophageal Reflux (GERD)
3. Peptic Esophagitis (Reflux Esophagitis)
4. Peptic Ulcer (Peptic Ulcers)
5. Ulcer

Related Drugs and Biologics

1. Omeprazole (Esomeprazole)
2. Antigen-Antibody Complex (Immune Complex)
3. Proteins (Proteins, Gene)
4. gamma-Globulins (gamma-Globulin)
5. Gastrins
6. Pentagastrin (Peptavlon)
7. Bile Acids and Salts (Bile Acids)
8. Collagen
9. Trypsin
10. Dinoprostone (PGE2)

Related Therapies and Procedures

1. Vagotomy
2. Proximal Gastric Vagotomy
3. Lung Transplantation
4. Immunotherapy
5. Ligation