|1.||Boykin, David W: 12 articles (08/2015 - 06/2006)|
|2.||Tidwell, Richard R: 10 articles (02/2015 - 06/2006)|
|3.||Brun, Reto: 10 articles (02/2015 - 07/2005)|
|4.||Wenzler, Tanja: 7 articles (08/2014 - 08/2007)|
|5.||Ismail, Mohamed A: 5 articles (08/2015 - 06/2006)|
|6.||Kumar, Arvind: 4 articles (08/2015 - 04/2007)|
|7.||Wilson, W David: 4 articles (12/2010 - 08/2007)|
|8.||Barrett, Michael P: 4 articles (12/2010 - 05/2003)|
|9.||Cotrim, Paulo C: 4 articles (09/2008 - 08/2003)|
|10.||Coelho, Adriano C: 4 articles (09/2008 - 08/2003)|
|1.||Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia)
03/01/1991 - "Our retrospective study for ultrasonic nebulised pentamidine in 13 patients shows that 7 of 8 patients with Pneumocystis carinii pneumonia (PCP), proven by biopsy examination, were cured (recovery rate, 88%). "
04/01/1990 - "Two patients on suspicion of beginning pneumocystis carinii pneumonia improved their clinical and radiological state with higher dosages of pentamidine. "
05/01/1994 - "The therapeutic efficacy of nebulised pentamidine in the prophylaxis of Pneumocystis carinii pneumonia (PCP) depends on the absolute pulmonary deposition of the drug. "
06/01/1990 - "We have recently demonstrated that substitution of imidazoline moieties for the amidine groups of pentamidine produces a molecule that is effective against rat Pneumocystis carinii pneumonia and that is apparently less toxic than pentamidine. "
07/01/1989 - "Pentamidine is effective in both the treatment and the prevention of Pneumocystis carinii pneumonia. "
|2.||Acquired Immunodeficiency Syndrome (AIDS)
06/01/1991 - "Intermittent therapy with aerosol pentamidine is highly effective and well tolerated as secondary prophylaxis for AIDS-related P. "
05/01/1993 - "As PcP prophylaxis with pentamidine aerosol is effective in patients with AIDS, we conducted a prospective trial with regular inhalations of pentamidine. "
10/01/1992 - "Since the prophylaxis of PcP with pentamidine-aerosol proved to be effective in patients with AIDS, we conducted a prospective trial with regular inhalations of pentamidine. "
04/01/1990 - "The sample size is too small to draw definitive conclusions concerning the efficacy of pentamidine aerosol in AIDS patients."
07/01/1994 - "A total of 121 HIV-infected patients with CD4+ cell counts < or = 200 x 10(6)/l or an AIDS diagnosis were enrolled in a controlled study of aerosolized pentamidine as primary PCP prophylaxis. "
07/01/2006 - "Compound 100 was highly efficacious against the infection at 20 mg/kg and 40 mg/kg, with > 1,000-fold reductions in burden, and resulted in improved survival curves versus those for pentamidine-treated mice (at the same doses). "
08/01/2010 - "Exception to this is infection with L guyanensis in French Guiana where systemic pentamidine is suggested as first-line treatment. "
02/01/1992 - "The in vitro infection could be cured readily with 80 micrograms/mL of SSG and 4 micrograms/mL of pentamidine in macrophages from normal animals. "
07/01/1990 - "From the promising activity exhibited by the pentamidine analogs in this in vitro study and their potential for reduced toxicity relative to the parent drug, pentamidine-related compounds hold promise as new agents for the treatment of protozoal infections."
11/15/2015 - "The cytotoxic effect of the best active natural product was evaluated on mouse peritoneal infected macrophages (IC50 = 0.47 ± 0.03 µg/ml in 24 h of culture), and the treatment revealed that DCTN never reaches toxic concentrations while reducing the infection and, most importantly, with no toxicity (>100 µg/ml with 0% of macrophage kill) when compared to pentamidine (37.5 µg/ml with 100% of macrophage kill). "
|4.||Visceral Leishmaniasis (Kala Azar)
04/01/1949 - "Treatment of kala-azar with pentamidine isothionate; a study of 55 cases."
10/01/2015 - "Use of Pentamidine As Secondary Prophylaxis to Prevent Visceral Leishmaniasis Relapse in HIV Infected Patients, the First Twelve Months of a Prospective Cohort Study."
09/01/2009 - "Pentamidine as secondary prophylaxis for visceral leishmaniasis in the immunocompromised host: report of four cases."
12/01/1997 - "Prophylaxis with monthly pentamidine was not useful in reducing relapses of visceral leishmaniasis."
11/01/1997 - "The activity of pentamidine-loaded nanoparticles was compared with that of free pentamidine in a BALB/c mice model of visceral leishmaniasis induced by Leishmania infantum. "
06/01/2001 - "Although frequently associated with discomfort, the two-injection course, giving a total of 8 mg pentamidine isethionate/kg, appears to be an effective treatment for cutaneous leishmaniasis in French Guiana. "
01/01/2000 - "Pentamidine isethionate is a safe and effective first-line treatment for Old World leishmaniasis. "
06/15/2006 - "Efficacy of short-course intramuscular pentamidine isethionate treatment on Old World localized cutaneous leishmaniasis in 2 patients."
11/01/2005 - "For New World leishmaniasis, parenteral antimonials represent the first-line treatment in all forms except those caused by Leishmania guyanensis in which pentamidine is preferable. "
05/01/2003 - "[A comparative study between the efficacy of pentamidine isothionate given in three doses for one week and N-methil-glucamine in a dose of 20mgSbV/day for 20 days to treat cutaneous leishmaniasis]."
|1.||Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)
|6.||Thymidine Monophosphate (TMP)
|1.||Transplantation (Transplant Recipients)
|3.||Drug Therapy (Chemotherapy)
|4.||Hematopoietic Stem Cell Transplantation