Bullous Pemphigoid (Pemphigoid)

03/01/2023 - "Super-potent topical corticosteroids (CS) are the mainstay of treatment for bullous pemphigoid. "
03/01/2004 - "To evaluate the efficacy of potent class I topical corticosteroids in relation to the affected body surface area (BSA) in patients with bullous pemphigoid and to review the literature. "
05/01/2009 - "Since high doses of superpotent topical corticosteroids (CS) have been shown to improve the survival of bullous pemphigoid (BP) patients and to be more effective than oral CS, few studies have described the long-term course of the disease of these patients. "
08/01/2021 - "Pemphigoid vegetans was diagnosed and treated successfully with oral corticosteroids. "
06/01/2009 - "Histopathological, immunological and serological data confirmed the diagnosis of localized bullous pemphigoid (BP) and treatment with systemic and local corticosteroids led to a sustained remission. "

07/20/2005 - "Very potent topical steroids are effective and safe treatments for bullous pemphigoid; their use in extensive disease may be limited by side effects and practical factors. "
01/01/2003 - "Very potent topical steroids are effective and safe treatments for bullous pemphigoid; their use in extensive disease may be limited by side effects and practical factors. "
11/01/2001 - "Evaluation of the safety and efficacy of a potent topical cortico-steroid in the treatment of bullous pemphigoid."
01/01/2011 - "The efficacy of topical steroids in bullous pemphigoid (BP) was assessed by prospective therapeutic trials. "
11/01/2016 - "Topical steroids are effective in treating bullous pemphigoid (BP). "

04/01/2023 - "Three cases of refractory bullous pemphigoid in the elderly treated successfully with ultra-low-dose rituximab."
01/01/2023 - "To study whether low-dose rituximab is also effective for bullous pemphigoid. "
01/01/2023 - "To study whether low-dose rituximab is also effective for bullous pemphigoid. "
03/01/2022 - "The efficacy of rituximab in patients with mucous membrane pemphigoid."
05/01/2020 - "Although rituximab demonstrates efficacy for clinical improvement and remission in pemphigoid, concern for adverse events may also limit the use of this medication. "

06/05/2023 - "Intravenous immunoglobulin (IVIg) has been reported to be an effective treatment for bullous pemphigoid. "
09/01/2001 - "Intravenous immunoglobulin is a safe and effective modality to treat mucous membrane pemphigoid. "
01/01/2023 - "To elucidate IVIG efficacy, we examined the improvement in disease severity based on the Bullous Pemphigoid Disease Area Index (BPDAI). "
02/01/2017 - "A randomized double-blind trial of intravenous immunoglobulin for bullous pemphigoid."
06/05/2023 - "IVIg approval is associated with lower in-hospital mortality and morbidity in inpatients with bullous pemphigoid."

10/01/1985 - "The highly specific binding of bullous pemphigoid autoantibodies to the hemidesmosome may prove helpful in future biochemical and immunocytochemical studies of this organelle."
07/01/2023 - "The objective of the present study was to explore the clinical characteristics of BP180NC16a autoantibody-positive mucous membrane pemphigoid. "
01/01/2023 - "In the present study, we aimed to analyze published data on cases and case series of anti-p200 pemphigoid with mucosal lesions and explored the potential contribution of anti-p200 autoantibodies to mucosal lesions. "
08/01/2019 - "Bullous pemphigoid (BP) autoantibody levels are generally elevated in patients with BP but can be present nonspecifically in patients without BP. To analyze the clinical findings of patients with elevated BP180 or BP230 autoantibody levels and negative direct immunofluorescence (DIF) study findings. "
01/01/2019 - "Basic research studies have now shed light on the pathogenic role of eosinophils and autoreactive T-helper 2 cells in pemphigoid, inducing tissue damage and sustaining autoantibody production by autoreactive B-cells, respectively. "

09/01/1998 - "Successful therapy for bullous pemphigoid with mycophenolate mofetil."
12/01/2013 - "[Anti-p200 pemphigoid: Remission under mycophenolate mofetil (Cellcept®)]."
12/01/2021 - "Towards therapeutic drug monitoring of mycophenolic acid in mucous membrane pemphigoid: A retrospective single-centre study."
01/01/2023 - "Here, we describe a case of a 74-year-old female with a history of recurrent bullous pemphigoid (BP) flares, who was on mycophenolate mofetil, and presented with skin lesions on her right thigh which were typical for her BP flares. "
02/01/2022 - "The Use of Mycophenolate Mofetil in the Treatment of Bullous Pemphigoid."

01/01/2021 - "What's more, it's helpful in deeper understanding of BP development and the relationship between BP and mucous membrane pemphigoid (MMP)."
01/01/2021 - "To quantitate the risk of relapse of ocular and extraocular disease among patients with mucous membrane pemphigoid (MMP) who had undergone drug-free remission. "
01/01/2018 - "This study explored the validity of the First International Consensus on Mucous Membrane Pemphigoid (MMP) guidance, which recommends that clinically indistinguishable patients, who have direct immunofluorescence (DIF)-negative biopsies, be excluded from a diagnosis of MMP. "
07/01/2014 - "The aim of this study was to evaluate tear film osmolarity in patients with ocular mucous membrane pemphigoid (MMP). "
02/01/2007 - "Very few studies have investigated the immunological status of a subset of MMP, termed oral pemphigoid (OP), presenting with exclusive oral lesions. "

01/01/2022 - "The gold standard for diagnosing bullous pemphigoid (BP) is the detection of linear deposition of IgG and/or C3 at the dermoepidermal junction using direct immunofluorescence (DIF). "
03/01/1999 - "Our data suggest that isotype switching from "inflammatory" IgG1 to "blocking" IgG4 antibody correlates with improvement in bullous pemphigoid."
11/01/2022 - "One patient microscopically demonstrated drug-associated and eosinophilic enriched LCV with DIF studies showing striking linear deposits of IgG suggestive of bullous pemphigoid, which was consistent with a vasculitic presentation of drug-induced bullous pemphigoid. "
05/08/2017 - "Linear IgG deposits along the basement membrane of adnexa has been proposed to be useful in the diagnosis of bullous pemphigoid (BP), but no controlled studies have been performed. "
04/01/2012 - "However, direct immunofluorescence studies demonstrated IgG and C3 linear deposition along the basement membrane zone, compatible with bullous pemphigoid. "

07/01/2020 - "Complete Remission in a Patient with Treatment Refractory Bullous Pemphigoid after a Single Dose of Omalizumab."
01/01/2020 - "Recently, omalizumab was reported to be effective in several patients with resistant bullous pemphigoid. "
01/01/2020 - "[EFFECTIVE TREATMENT FOR BULLOUS PEMPHIGOID WITH OMALIZUMAB]."
05/01/2023 - "Research progress of omalizumab in the treatment of bullous pemphigoid."
07/01/2022 - "Embase, PubMed, Cochrane, and clinicaltrials.gov were searched for English and French articles published from inception to July 1, 2021, using search terms "omalizumab" OR "Xolair" OR "IGE025" OR "olizumab" AND "bullous pemphigoid." Screening and data extraction was performed by two raters independently. "

01/01/2022 - "Association of Immunosuppressants with Mortality of Patients with Bullous Pemphigoid: A Nationwide Population-Based Cohort Study."
09/01/2014 - "Bullous pemphigoid (BP) responds to a variety of immunosuppressive agents and usually controls, but does not cure, the disease. "
01/01/1987 - "Under treatment with immunosuppressants the cell counts returned to normal suggesting a T helper cell activation to be involved in the acute stage of bullous pemphigoid."
05/01/2012 - "The few randomized clinical trials conducted to date of patients with pemphigus and bullous pemphigoid report a similar efficacy for MMF to other immunosuppressants."
10/01/2011 - "The few randomized clinical trials conducted to date of patients with pemphigus and bullous pemphigoid report a similar efficacy for MMF to other immunosuppressants."

07/01/2022 - "A Cox regression analysis showed an increased probability of reaching complete remission on minimal therapy or off therapy with the combined therapy (hazard ratio = 2.28 [1.28-4.07], p = 0.005) after age, Bullous Pemphigoid Disease Activity Index score, and underlying diseases were controlled. "
04/01/1992 - "To identify factors predictive of outcome, 16 patients with "good prognosis bullous pemphigoid" (no systemic treatment or in remission within 2 years) were compared with 12 patients with recurrent disease requiring maintenance therapy who still needed treatment after 3 years or longer. "
01/01/2007 - "B-cell targeted therapy alone may not be effective in bullous pemphigoid."
10/01/2013 - "Bullous pemphigoid: a case series with emphasis on long-term remission off therapy."
10/01/2021 - "A blistering new era for bullous pemphigoid: A scoping review of current therapies, ongoing clinical trials, and future directions."

09/01/1984 - "41 patients with pemphigoid entered a multicentre randomised study of the efficacy of plasma exchange. "
09/01/1984 - "Plasma exchange in bullous pemphigoid."
09/03/1983 - "[Bullous pemphigoid treated by plasma exchange. "
05/03/1980 - "[Treatment of bullous pemphigoid by plasma exchanges--two cases (author's transl)]."
12/01/2022 - "Therapeutic plasma exchange as adjunct therapy for bullous pemphigoid."

12/01/2023 - "Double filtration plasmapheresis for bullous pemphigoid: Outcomes from the evaluation of eight patients."
02/01/2022 - "Plasmapheresis: a feasible choice for bullous pemphigoid patients infected with SARS-CoV-2."
04/01/2014 - "Clinical and serological responses following plasmapheresis in bullous pemphigoid: two case reports and a review of the literature."
04/01/2003 - "We report a case of bullous pemphigoid successfully treated with double filtration plasmapheresis. "
12/01/2001 - "Double filtration plasmapheresis for the treatment of bullous pemphigoid: a three case report."

12/01/2022 - "A retrospective case series of 20 patients with immunotherapy-induced bullous pemphigoid with emphasis on management outcomes."
07/01/2022 - "The iso-oncotopic response: immunotherapy-associated bullous pemphigoid in tumour footprints."
07/01/2021 - "Bullous pemphigoid is a serious and rare complication of immunotherapy. "
07/01/2021 - "A Rare Case of Bullous Pemphigoid Secondary to Checkpoint Inhibitor Immunotherapy: A Tense Situation."
01/01/2019 - "Immunotherapy-induced bullous pemphigoid (BP) is an uncommon but established reaction that portends significant management implications as in most instances systemic treatment is required. "

01/01/2001 - "16 patients were treated with amnion membrane transplantation because of: pemphigoid ocularis, combustio chaemica, ulcus corneae, keratopathia bullosa, descemetocele, symblepharon, graft disease. "
05/01/1997 - "After separation of symblepharons in ocular pemphigoid, transplantation of nasal or bucal mucosa is recommended to prevent recurrent lid fusion; however, it is not always successful. "
10/01/1995 - "A total of nine patients (3 with chemical injury, 3 with limbal deficiency with unknown etiology, 2 with moderate ocular pemphigoid [OCP], and 1 with traumatic limbal deficiency) were treated by limbal allograft transplantation. "
10/04/2023 - "Risk of de novo bullous pemphigoid and pemphigus following transplantation: A global wide-scale cohort study."
10/01/2004 - "Recent developments on mucous membrane pemphigoid surgical therapy include keratolimbal allografts and amniotic membrane transplantation, with or without penetrating keratoplasty for ocular surface reconstruction in total stem cell deficiency. "