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Benign Mucous Membrane Pemphigoid (Cicatricial Pemphigoid)

A chronic blistering disease with predilection for mucous membranes and less frequently the skin, and with a tendency to scarring. It is sometimes called ocular pemphigoid because of conjunctival mucous membrane involvement.
Also Known As:
Cicatricial Pemphigoid; Pemphigoid, Benign Mucous Membrane; Benign Mucosal Pemphigoid; Cicatricial Pemphigoid, Ocular; Mucous Membrane Pemphigoid, Benign; Ocular Cicatricial Pemphigoid; Pemphigoid, Ocular Cicatricial; Benign Mucosal Pemphigoids; Cicatricial Pemphigoids, Ocular; Mucosal Pemphigoid, Benign; Mucosal Pemphigoids, Benign; Ocular Cicatricial Pemphigoids; Pemphigoid, Benign Mucosal; Pemphigoids, Benign Mucosal; Pemphigoids, Ocular Cicatricial; Pemphigoid, Cicatricial
Networked: 417 relevant articles (17 outcomes, 46 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Graft vs Host Disease (Graft-Versus-Host Disease)
2. Blister (Bulla)
3. Chemical Burns (Chemical Burn)
4. Stevens-Johnson Syndrome
5. Lichen Planus (Lichen Ruber Planus)

Experts

1. Foster, C Stephen: 15 articles (01/2014 - 07/2002)
2. Ahmed, A Razzaque: 11 articles (11/2013 - 07/2002)
3. Ahmed, A R: 9 articles (11/2007 - 09/2000)
4. Yancey, Kim B: 8 articles (06/2008 - 12/2002)
5. Hashimoto, Takashi: 8 articles (01/2008 - 01/2002)
6. Yancey, K B: 8 articles (11/2001 - 01/2000)
7. Lazarova, Z: 7 articles (11/2006 - 01/2000)
8. Zillikens, Detlef: 7 articles (09/2006 - 01/2002)
9. Foster, C S: 6 articles (11/2007 - 09/2000)
10. Zillikens, D: 6 articles (12/2001 - 01/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Benign Mucous Membrane Pemphigoid:
1. Tetracycline (Achromycin)FDA LinkGeneric
2. Mitomycin (Mitomycin-C)FDA LinkGeneric
3. DapsoneFDA Link
4. Niacinamide (Nicotinamide)FDA LinkGeneric
5. Ophthalmic Solutions (Eye Drops)IBA
01/01/2010 - "In severe cases, such as Sjoegren's syndrome, Stevens-Johnson syndrome or ocular cicatricial pemphigoid, therapy with artificial tears can be insufficient to relieve severe discomfort. "
05/01/1996 - "A similar process, limited only to the conjunctiva, observed in some patients using eye drops for the treatment of glaucoma, is called pseudo-ocular cicatricial pemphigoid (P-OCP). "
07/01/2015 - "In severe cases, such as Sjogren's syndrome, Stevens-Johnson syndrome, or ocular cicatricial pemphigoid, therapy with artificial tears is often insufficient to relieve severe discomfort, prevent progressive ocular surface disease, or enable visual rehabilitation by corneal transplantation. "
07/01/1996 - "Fourteen eyes of 11 patients with cicatricial keratoconjunctivitis (seven patients with cicatricial pemphigoid and four with Stevens-Johnson syndrome; average age +/- S.D., 55.5 +/- 25.4 years) were treated with a combination of allograft limbal transplantation, amniotic membrane transplantation, and tarsorrhaphy, followed every 15 minutes by artificial tears derived from the patient's blood serum. "
11/01/2008 - "Autologous serum eye drops have been reported to be effective for the treatment of severe dry eye-related ocular surface disorders (Sjögren's syndrome), and also other entities such as superior limbic keratoconjunctivitis, graft-versus-host disease, Stevens-Johnson syndrome, ocular cicatricial pemphigoid, recurrent or persistent corneal erosions, neurotrophic keratopathy, Mooren's ulcer, aniridic keratopathy, filtering blebs after trabeculectomy, and post-keratorefractive surgery. "
6. kalininIBA
7. Immunoglobulin A (IgA)IBA
8. CollagenIBA
9. Immunoglobulins (Immunoglobulin)IBA
10. Tacrolimus (Prograf)FDA LinkGeneric

Therapies and Procedures

1. Transplants (Transplant)
2. Immunomodulation
3. Trabeculectomy (Trabeculoplasty)
4. Cryotherapy (Therapy, Cold)
5. Transplantation (Transplant Recipients)