Secondary Parkinson Disease (Secondary Parkinsonism)
32
relevant articles (0 outcomes,
5 trials/studies)
found for this Disease
Description:
Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)
Also Known As:
Secondary Parkinsonism; Parkinson Disease, Secondary; Parkinson Disease, Secondary Vascular; Parkinson Disease, Symptomatic; Parkinsonism, Secondary; Parkinsonism, Symptomatic; Secondary Vascular Parkinson Disease; Parkinsonism, Atherosclerotic; Symptomatic Parkinsonism; Atherosclerotic Parkinsonism; Symptomatic Parkinson Disease
Disease Context: Research Results
Related Diseases
Experts
Drugs and Biologics
Drugs and Important Biological Agents (IBA) related to Secondary Parkinson Disease:
| 1. | 1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
01/01/1993
- " In this debate, while MPTP has proven to be a most amenable model for the study of secondary parkinsonism it has not resolved the dilemma; equally uncertain are the claims derived from the MPTP hypothesis of nigral vulnerability that selective MAO inhibition has a protective effect on the natural history of Parkinson's disease" 08/01/1998
- " From observations in brain of patients with secondary parkinsonism, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine parkinsonism in the rhesus monkey, as well as the regional DA transporter distribution in the primate substantia nigra, it is concluded that PD may be caused by any exogenous and/or endogenous toxin using the transporter system for DA and to some degree the other brain monoamines (noradrenaline, serotonin), to enter, and damage, the respective monoamine neurons"
Get all the results and reference details, order at left...
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| 2. | Antipsychotic Agents (Antipsychotics)IBA
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| 3. | alpha-SynucleinIBA
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| 4. | Monoamine Oxidase (MAO)IBA
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| 5. | Histamine (Histamine Dihydrochloride)IBA
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| 6. | Direction compoundIBA
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| 7. | Levodopa (L Dopa)FDA LinkGeneric
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| 8. | Sertraline (Zoloft)FDA LinkGeneric
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| 9. | Meperidine (Pethidine)FDA LinkGeneric
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| 10. | Dihydroxyphenylalanine (Dopa)IBA
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| 37 Drugs and Important Bio-Agents
and
31
more articles analyzed in the Research Interface, order at left...
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Therapies and Procedures