Paramethasone

A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than HYDROCORTISONE with supplementary FLUDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p737)

Also Known As:

Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-16-methyl-, (6alpha,11beta,16alpha)-

Networked: 25 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Fluorinated Steroids: 32
      - Paramethasone: 25
        paramethasone acetate: 12
    - Pregnanes: 9
      - Pregnadienes
        Pregnadienetriols
        Paramethasone: 25
        paramethasone acetate: 12

Experts

1.	Bel, Ivan: 1 article (06/2006)
2.	Gomar, Carmen: 1 article (06/2006)
3.	Moreno, Luis-Alfonso: 1 article (06/2006)
4.	Barriocanal Barriocanal, Ana M: 1 article (06/2005)
5.	Olivé Marques, Alejandro: 1 article (06/2005)
6.	Pérez-Andrés, Ricardo: 1 article (06/2005)
7.	Vaqué Cabañas, Anna: 1 article (06/2005)
8.	Amat, P: 1 article (02/2000)
9.	Lluch, M: 1 article (02/2000)
10.	Malet, A: 1 article (02/2000)

Related Diseases

1.	Rheumatoid Arthritis 01/01/1973 - "[Paramethasone in rheumatoid arthritis. " 03/01/1964 - "[4 YEARS' EXPERIENCE WITH PARAMETHASONE IN THE TREATMENT OF RHEUMATOID ARTHRITIS]." 12/01/1962 - "[Clinical trials with 6 alpha-fluoro-16 alpha-methylprednisolone (paramethasone) in rheumatoid arthritis]." 01/01/1973 - "Posterior subcapsular cataract in rheumatoid arthritis patients after long-term, low-dosage paramethasone therapy."
2.	Arthritis (Polyarthritis) 10/01/1964 - "[PARAMETHASONE IN THE THERAPY OF CHRONIC POLYARTHRITIS]." 08/01/1985 - "The mice were protected from the development of arthritis by treatment with paramethasone (0.25 mg/kg/day) or cyclophosphamide (5 mg/kg/day). " 03/01/1966 - "A controlled study of two preparations, paramethasone, propoxyphene, and aspirin and propoxyphene and aspirin in the treatment of arthritis."
3.	Atrophy 03/20/1966 - "[Histological and enzyme histochemical studies on adrenocortical atrophy induced by hydrocortisone, dexamethasone and paramethasone]."
4.	Asthma (Bronchial Asthma) 01/01/1976 - "[Clinical evaluation of triamcinolone and paramethasone in the treatment of chronic asthma]." 09/01/1965 - "[The dosage of betamethasone and paramethasone in bronchial asthma]." 04/24/1965 - "DOSAGE OF BETAMETHASONE AND PARAMETHASONE IN ASTHMA." 01/16/1966 - "[Therapy of chronic asthma with a new corticosteroid: acetate of paramethasone]."
5.	Intracranial Hypotension 06/01/2006 - "Epidural dextran-40 and paramethasone injection for treatment of spontaneous intracranial hypotension." 06/01/2006 - "This report describes treatment with epidural dextran-40 and paramethasone injection of postural headache resulting from spontaneous intracranial hypotension in a pregnant patient. " 06/01/2006 - "We report a case of spontaneous intracranial hypotension in a pregnant patient successfully treated by epidural injection of dextran-40 and paramethasone, with adjuvant oral steroid therapy. "

Related Drugs and Biologics

1.	Dexamethasone (Maxidex)
2.	Dextropropoxyphene (Darvon)
3.	Methylprednisolone
4.	Hydrocortisone (Cortisol)
5.	Enzymes
6.	Aspirin (Acetylsalicylic Acid)
7.	Adrenal Cortex Hormones (Corticosteroids)
8.	Triamcinolone (Aristocort)
9.	Betamethasone (Celestone)
10.	Trypsin Inhibitors

Related Therapies and Procedures

1.	Therapeutics
2.	Intra-Articular Injections
3.	Epidural Injections