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Familial Periodic Paralyses (Normokalemic Periodic Paralysis)

A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481)
Also Known As:
Normokalemic Periodic Paralysis; Familial Periodic Paralysis; Paralyses, Familial Periodic; Normokalemic Periodic Paralyses; Paralyses, Normokalemic Periodic; Paralysis, Familial Periodic; Paralysis, Normokalemic Periodic; Periodic Paralyses, Familial; Periodic Paralyses, Normokalemic; Periodic Paralysis, Normokalemic; Periodic Paralysis, Familial
Networked: 61 relevant articles (0 outcomes, 5 trials/studies)

Disease Context: Research Results

Related Diseases

1. Hyperkalemic Periodic Paralysis (Periodic Paralysis, Hyperkalemic)
2. Renovascular Hypertension (Goldblatt Syndrome)
3. Bartter Syndrome (Syndrome, Bartter)
4. Paralysis (Palsy)
5. Hypokalemic Periodic Paralysis (Periodic Paralysis, Hypokalemic)

Experts

1. Lin, Shih-Hua: 2 articles (04/2012 - 01/2003)
2. Scheuer, Todd: 2 articles (08/2010 - 12/2008)
3. Catterall, William A: 2 articles (08/2010 - 12/2008)
4. Sokolov, Stanislav: 2 articles (08/2010 - 12/2008)
5. Fournier, E: 2 articles (12/2005 - 12/2004)
6. Wu, Lei: 1 article (07/2014)
7. Zhang, Baorong: 1 article (07/2014)
8. Wu, Weiping: 1 article (07/2014)
9. Kang, Ying: 1 article (07/2014)
10. Noto, Yu-ichi: 1 article (01/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Familial Periodic Paralyses:
1. Sodium Channels (Sodium Channel)IBA
2. PotassiumIBA
3. Captopril (Capoten)FDA LinkGeneric
4. SodiumIBA
5. Acetazolamide (Diamox)FDA LinkGeneric
6. Ion Channels (Ion Channel)IBA
7. Atracurium (Tracrium)FDA Link
8. Propofol (Diprivan)FDA LinkGeneric
9. Creatine Kinase (Creatine Phosphokinase)IBA
10. Potassium CitrateFDA LinkGeneric

Therapies and Procedures

1. Nursing Care
2. Anesthesia
3. Tonsillectomy
4. Intravenous Injections
5. Coronary Artery Bypass (Coronary Artery Bypass Surgery)