Pancreatic Diseases (Pancreatic Disease)

01/01/1964 - "[RENAL CLEARANCE OF AMYLASE IN THE NORMAL STATE AND IN PANCREATIC DISEASES]."
06/01/2019 - "The present evidence suggests a significant link between serum amylase activity and ABO blood type in the study population, indicating ABO blood type may be associated with the susceptibility of pancreatic disease."
11/14/1952 - "[Curves of lipases and amylases in the blood produced by carbaminoylcholine; value in the study of chronic pancreatic diseases]."
11/12/2023 - "The difficult process of diagnosis was aided by the further analysis of the sputum, which showed significantly elevated amylase without any evidence of pancreatic disease. "
12/02/2022 - "The blood amylase level of the children with pancreatic diseases was significantly lower than that before ERCP (t=7.73, P<0.001). "

06/01/1998 - "The results of this study, requiring confirmation, suggest that the polymorphism of GSTM1 and NAT1 enzymes may be associated with a modest increase in susceptibility to pancreatic diseases."
04/01/1960 - "The combined study of serum enzymes and duodenal contents in the diagnosis of pancreatic disease."
09/01/2023 - "Benign pancreatic hyperenzymemia (BPH) or Gullo's syndrome is a benign condition consisting of an oscillating elevation of pancreatic enzymes without the identification of pancreatic disease. "
11/01/2022 - "Endoplasmic reticulum (ER) stress-inducing variants in several pancreatic secretory enzymes have been associated with pancreatic disease. "
05/11/2021 - "As the number of IBD incidences with concomitant pancreatic diseases is constantly increasing in the pediatric population, it is important to include pancreatic enzymes level measurement in the workup of IBD."

01/01/1991 - "The present study evaluated serum ribonuclease activity (SRA) in patients with inflammatory and neoplastic pancreatic diseases. "
04/01/1983 - "[Studies on ribonuclease in the pancreatic juice of patient with pancreatic disease. "
06/01/1981 - "[Studies on ribonucleases in the pancreatic juice of patients with pancreatic disease. "
01/01/1991 - "Serum ribonuclease activity in the diagnosis of pancreatic disease."
01/01/1991 - "RNase was also increased in a high number of patients with pancreatic diseases, but was not correlated with pancreatic damage. "

08/01/1988 - "Fractional urinary clearance of immunoreactive lipase in chronic pancreatic disease."
05/01/2020 - "To characterize inflammatory and neoplastic pancreatic diseases of dogs and to correlate these findings with clinical findings and canine pancreatic lipase immunoreactivity (cPLI) results. "
01/01/2020 - "Histopathology and Feline Pancreatic Lipase Immunoreactivity in Inflammatory, Hyperplastic and Neoplastic Pancreatic Diseases in Cats."
01/16/2014 - "We followed up this patient for two years with blood tests every six months and she did not show any signs or symptoms of pancreatic disease, except for the high level of lipase serum. "
07/01/2006 - "A diagnosis of pancreatic disease was made on the findings of marked elevations of serum lipase concentrations and ultrasonographic identification of pancreatic masses in both cases. "

01/01/2003 - "The measurement of fecal elastase 1 concentrations (FEC) has been used as a screening tool for exocrine pancreatic disease in different patient groups indicating a high prevalence of exocrine dysfunction in diabetic populations. "
07/01/2002 - "How useful is fecal pancreatic elastase 1 as a marker of exocrine pancreatic disease?"
09/01/1998 - "The determination of faecal pancreatic elastase 1 is a reliable test for the diagnosis of chronic pancreatic diseases in man due to its high sensitivity and specificity (93%). "
02/15/1992 - "Abdominal ultrasonographic examination and measurement of serum elastase 1 levels were done within 2 weeks after the initial visit to the clinic in a total of 2098 patients older than 35 years of age with symptoms suggesting pancreatic disease. "
01/01/1992 - "A significant inverse relationship between the binding capacity of alpha 2-M and the activity of the endogenous elastase bound to alpha 2-M was seen in various pancreatic diseases.(ABSTRACT TRUNCATED AT 250 WORDS)"

01/01/2012 - "Improved diagnostic accuracy of pancreatic diseases with a combination of various novel serum biomarkers--case control study from Manipal Teaching Hospital, Pokhara, Nepal."
01/01/2021 - "The CPDPC is now also turning to developing clinically useful biomarkers, and initiating clinical trials in these difficult to treat pancreatic diseases. "
07/01/2008 - "Despite this, our study clearly demonstrates that urine is a valid source of noninvasive biomarkers in patients with pancreatic diseases."
05/01/2005 - "The purpose of this study was to compare exfoliative bile cytology and biomarkers of the bile in patients with hepatobiliary and pancreatic diseases. "
11/01/2003 - "The anatomic position and relationships of the pancreas make direct observation of pancreatic pathology difficult, so the diagnosis of pancreatic disease is typically based on the measurement of biochemical markers in serum and imaging studies of the abdomen. "

01/01/1978 - "The purpose of this study was to compare the diagnostic efficacy of endoscopic retrograde pancreatography (ERP) and secretin-CCK test for the diagnosis of pancreatic disease. "
01/01/2017 - "In the reproducibility study and clinical experience, 31 patients with suspected pancreatic disease underwent 33 secretin-enhanced magnetic resonance cholangiopancreatography exams. "
01/01/1976 - "[The pancreatic stimulation test with secretin in the study of chronic pancreatic diseases]."
09/15/1965 - "[Secretin studies in the diagnosis of pancreatic diseases]."
08/01/1950 - "Studies in pancreatic function; a statistical study of pancreatic secretion following secretin in patients without pancreatic disease."

05/12/1982 - "[Value of the radioimmunologic measurement of serum trypsin in the study of pancreatic diseases. "
01/01/2023 - "The determination of trypsin activity in human urine is important for evaluating pancreatic disease. "
11/01/2020 - "The determination of trypsin in the human real sample is a routine medical investigation to assess the pancreatic disease. "
09/15/2006 - "Our biosensor detected low trypsin concentrations down to 42 pM with a response time of approximately 10 min, making it a very sensitive device in the detection of lower trypsin levels with such future putative applications as the diagnosis of pancreatic diseases."
01/01/2000 - "To evaluate trypsin activity in the small intestine of healthy volunteers and patients with pancreatic disease by a recently developed (13)C-egg white breath test. "

05/01/2017 - "At Dartmouth-Hitchcock Medical Center (DHMC),we have developed and validated a microRNA (miRNA) panel for patients with pancreatic diseases that can be used in association with the gold standard method for diagnosis. "
10/01/2008 - "To the best of our knowledge, this study is the first to evaluate the diagnostic potential of miRNAs in a clinical setting and has shown that miRNA analysis of pancreatic FNA biopsy samples can aid in the pathologic evaluation of suspicious cases and may provide a new strategy for improving the diagnosis of pancreatic diseases."
11/29/2023 - "The plasma sEV miRNA diagnostic signature (d-signature) selected using the three machine learning methods could distinguish PDAC patients from non-PDAC individuals, HC, and benign pancreatic disease (BPD, CP plus BPT) both in training and validation cohort. "
07/05/2016 - "We gain insight of the association between the aberrant plasma miRNA expression and pancreatic disease. "
01/01/2014 - "A marked difference in the profiles of four circulating miRNAs (miR-205, miR-210, miR-492, and miR-1427) was observed in pancreatic juice collected from patients with PDAC and those without pancreatic disease. "

05/07/2021 - "CA19-9 is one of the most widely used tumor markers in biliary-pancreatic diseases. "
10/01/2016 - "NLR >5 could independently predict the occurrence of PDACs in pancreatic neoplastic disease irrespective of other tumor markers, CEA and CA19-9, in pancreatic disease."
09/07/2005 - "Novel serum tumor marker, RCAS1, in pancreatic diseases."
03/01/1993 - "Knowledge of the Lewis phenotype may therefore add vital information when tumor marker assays are used for diagnosis and monitoring of malignant pancreatic disease."
05/01/1991 - "The tumor markers CEA, CA 19-9, CA-50, CA-195, and TATI were analyzed in patients with pancreatic diseases as well as disorders in the upper quadrant of the abdomen. "

10/01/2016 - "Endoscopic retrograde cholangiopancreatography (ERCP) is the gold-standard modality for diagnosis and therapy of bilio-pancreatic disease. "
10/31/2018 - "In this review, we will summarize the progress toward the development of gene therapies for pancreatic diseases, with an emphasis on recent preclinical studies and clinical trials. "
12/20/2009 - "The purpose of this study was to evaluate ERCP for the diagnosis and therapy of biliary-pancreatic diseases. "
06/01/2005 - "Embryonic stem (ES) cells have been proposed to be a powerful tool in the study of pancreatic disease, as well as a potential source for cell replacement therapy in the treatment of diabetes. "
01/01/1999 - "Based on this study, we suggest that antiangiogenesis might be a novel target for prevention or therapy in chronic pancreatic diseases."

01/01/2005 - "Safety and efficacy of laparoscopic distal pancreatectomy for the treatment of pancreatic disease."
11/07/2023 - "All patients who received distal pancreatectomy for PDAC from 2016 to 2020 at the Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiaotong University School of Medicine were considered for the study. "
09/01/2017 - "The study included 183 consecutive patients who underwent distal pancreatectomy from February 2007 to January 2017, including 75 cases of PDAC and 108 cases of other pancreatic disease. "
04/01/2016 - "Recent studies have reported encouraging results of non-traditional pancreatic resections, including central pancreatectomy (CP), for central pancreatic disease. "
12/01/2013 - "We searched the electronic databases PubMed and EMBASE for studies comparing RP with laparoscopic pancreatectomy (LP) and open pancreatectomy (OP) for patients with pancreatic disease from June 2009 to June 2012. "

01/01/2008 - "Although pancreaticoduodenectomy has become a safe and effective procedure for benign and malignant pancreatic diseases in recent years, leakage of pancreaticoenteric anastomosis still remains a major cause of morbidity and even mortality. "
12/27/2021 - "The trial is designed to enroll and randomly assign 244 patients with an indication for elective pancreatoduodenectomy for malignant periampullary and pancreatic lesions, as well as premalignant and symptomatic benign periampullary and pancreatic disease. "
05/01/2017 - "Total pancreaticoduodenectomy is performed for treating benign and borderline pancreatic disease involving the whole pancreas. "
09/01/1999 - "There have been increasing changes in the role of pancreatoduodenectomy (PD) in the management of benign and malignant pancreatic disease. "
09/01/1997 - "This method has been performed in 35 duodenopancreatectomy (malignant pancreatic disease: 32 patients, benign pancreatic disease: 3 patients). "

01/01/2021 - "Probe-based confocal laser endomicroscopy may be effective for the diagnosis of pancreatic diseases as adjunct modality. "
01/01/2016 - "the aim of study was testing and introduction in clinical practice combination of EUS with sonoelastography, fine-needle biopsy and needle-based confocal laser endomicroscopy in advanced diagnostic of pancreatic disease. "
01/01/2021 - "Ninety-eight drainage fluid samples obtained from 22 patients with hepatobiliary pancreatic disease were analyzed to identify microorganisms using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) with a new membrane filtration protocol and rapid BACpro® pretreatment compared to sole rapid BACpro® pretreatment. "
05/01/2020 - "EUS-guided needle-based confocal laser endomicroscopy (nCLE) is a novel minimally invasive imaging technique in diagnosis of pancreatic diseases. "
04/01/2014 - "In this study, laser capture microdissection was applied to extract the islets from an organ donor that died at onset of type 1 diabetes and from an organ donor without pancreatic disease. "

01/01/2013 - "A low-fat diet may be effective in patients with dyspepsia associated with endosonographic evidence of mild pancreatic disease, who do not habitually drink alcohol."
01/01/2013 - "The objective of this study was to examine the efficacy of low-fat diet against dyspepsia in patients who had endosonographic evidence of nonalcoholic mild pancreatic disease. "
01/01/2013 - "Efficacy of low-fat diet against dyspepsia associated with nonalcoholic mild pancreatic disease diagnosed using the Rosemont criteria."
01/01/2013 - "Patients with unknown cause of upper abdominal pain suggesting pancreatic disease without a history of alcohol consumption were prescribed a low-fat diet (<20 g of fat/d) for 4 weeks. "
12/01/1986 - "The mean values for total fatty acid outputs (after back transformation of the logged data) were significantly higher in each subgroup of patients with pancreatic disease on their usual diets (acute 134, chronic 189, cancer 235 mg) than in the two subgroups of controls (30 and 55 mg), due to significant increases in the outputs of every fatty acid, C16:0 through to C22:5. This finding, which was usually not apparent in patients with pancreatic disease on low-fat diets, may reflect the combined influence of dietary fat intakes and hepatic enzyme induction. "