Pancreatic Cyst

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97 relevant articles (0 outcomes, 3 trials/studies) found for this Disease

Description: A true cyst of the PANCREAS, distinguished from the much more common PANCREATIC PSEUDOCYST by possessing a lining of mucous EPITHELIUM. Pancreatic cysts are categorized as congenital, retention, neoplastic, parasitic, enterogenous, or dermoid. Congenital cysts occur more frequently as solitary cysts but may be multiple. Retention cysts are gross enlargements of PANCREATIC DUCTS secondary to ductal obstruction. (From Bockus Gastroenterology, 4th ed, p4145)

Also Known As:

Cyst, Pancreatic; Cysts, Pancreatic; Pancreatic Cysts

Disease Context: Research Results

Neoplasms: 387640

Cysts: 11466

Pancreatic Cyst: 97

Pancreatic Pseudocyst: 261

Digestive System Diseases: 29

Pancreatic Diseases: 923

Pancreatic Cyst: 97

Pancreatic Pseudocyst: 261

Related Diseases

1.	Hemangioblastoma
2.	Pheochromocytoma
3.	Neoplasms (Cancer)
4.	Carcinoma (Carcinomatosis)
5.	Hemangioma (Angioma)

Experts

1.	McHenry, Lee: 1 article (02/2008)
2.	Dutkevitch, Sarah: 1 article (02/2008)
3.	Sherman, Stuart: 1 article (02/2008)
4.	Howard, Thomas J: 1 article (02/2008)
5.	Wentz, Sabrina: 1 article (02/2008)
6.	DeWitt, John: 1 article (02/2008)
7.	Dewitt, John: 1 article (02/2008)
8.	Lillemoe, Keith D: 1 article (02/2008)
9.	Schmidt, C Max: 1 article (02/2008)
10.	Ralstin, Matthew C: 1 article (02/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pancreatic Cyst:

1.	Retinaldehyde (Retinal)IBA 03/01/2004 - "The major clinical manifestations include retinal angiomas, central nervous system hemangioblastomas, pheopleochromocytoma, pancreatic cysts, epididymal cystoadenomas and renal lesions" 12/01/2007 - "There were 2 patients who developed renal and pancreatic cysts, 3 patients retinal hemangioblastoma, and 2 others epididymic cysts" 03/01/2004 - "The patient showed retinal angiomatosis, cerebellar hemangioblastomas, multiple pancreatic cysts, right kidney with polycystic features plus two RCC" 02/01/2004 - "The common lesions of 18 patients in the large kindred were: renal cell carcinomas (56%), CNS hemangioblastomas(50%),retinal angiomas(28%), and multiple pancreatic cysts(39%)" 04/01/2002 - "Germ-line mutation of the von Hippel-Lindau (VHL) gene predisposes to the development of multifocal, benign lesions, including retinal and central nervous system hemangioblastomas, pheochromocytomas, and renal and pancreatic cysts" Order ALL the reference details at left...
2.	Biological Tumor Markers (Tumor Markers)IBA 08/01/2000 - "CONCLUSION: When a unilocular pancreatic cyst is found, without history of pancreatitis and gallstones, having low serum tumor markers levels and negativity of CA 72-4 and MCA in the cyst fluid, the diagnosis of the macrocystic variant of the serous cystadenoma may be suggested" 01/01/1996 - "Previous studies have shown that malignant mucinous tumors differ from benign pancreatic cysts in proliferative activity, secretion of tumor markers, and expression of growth factor receptors" 01/01/1993 - "In an attempt to develop new preoperative diagnostic criteria to assist in decisions regarding therapy, the authors have performed cyst fluid analysis for tumor markers (carcinoembryonic antigen: CEA, CA 125, and CA 19.9), amylase content, amylase isoenzymes, relative viscosity, and cytology on 26 pancreatic cysts" Order ALL the reference details at left...
3.	Growth Factor ReceptorsIBA 01/01/1996 - "Previous studies have shown that malignant mucinous tumors differ from benign pancreatic cysts in proliferative activity, secretion of tumor markers, and expression of growth factor receptors" 01/01/1996 - "CONCLUSIONS: Elevated levels of the proliferation antigen TPA in malignant pancreatic cysts correlate with earlier observations of increased proliferative activity and overexpression of growth factor receptors in these tumors" Order ALL the reference details at left...
4.	Insulin (Novolin)FDA Link 01/17/1980 - "Subsequent studies of the patient's insulin (fortuitously obtained from his pancreas during a laparotomy for a pancreatic cyst) have confirmed this conclusion" Order ALL the reference details at left...
5.	AmylasesIBA 03/01/1968 - "Blood amylase in patients with pancreatic cyst]" 11/01/1980 - "Report of a case with pancreatic cyst associated with amylase rich left hemothorax subsequently occurring with right hydropneumothorax (author's transl)]" 08/01/2004 - "In conclusion, cyst fluid analysis for cytology, mucin staining, CEA, and amylase levels are useful in the differential diagnosis of pancreatic cysts." 07/01/1991 - "The contents obtained by fine needle aspiration (FNA) from 41 pancreatic cysts in 32 patients were studied cytologically and assayed for amylase and carcinoembryonic antigen (CEA) levels, which have been shown to discriminate pancreatic pseudocysts from mucinous cystic neoplasms and necrotic cystic carcinomas" 12/01/1995 - "In order to improve the pre-operative recognition of these lesions, we performed cyst fluid analysis for enzymes (amylase and lipase), tumour markers (CEA, CA 19-9, CA 125, CA 72-4), and cytology in 52 pancreatic cysts" Order ALL the reference details at left...
6.	EnzymesIBA 03/10/1963 - "Pleurisy due to pancreatic enzymes occurring after excision of a pancreatic cyst" 02/01/1978 - "The mechanisms for the development of this lesion are: 1. direct extension of the pancreatic cyst into the splenic hilum; 2. digestive effects of pancreatic enzymes on splenic vasculature and parenchyma; 3. pancreatitis occurring in ectopic intrasplenic pancreatic tissue and 4. liquefaction of splenic infarcts secondary to thrombosis of the splenic vessels" 12/01/1995 - "In order to improve the pre-operative recognition of these lesions, we performed cyst fluid analysis for enzymes (amylase and lipase), tumour markers (CEA, CA 19-9, CA 125, CA 72-4), and cytology in 52 pancreatic cysts" 01/01/1989 - "Among the patients with chronic pancreatitis, either in painful relapse (N = 19) or with pancreatic cysts (N = 15), the respective percentages of enzymes elevations were: 79 and 80% for elastase 1, 68 and 67% for trypsinogen, 63 and 73% for pancreatic isoamylase, 58 and 60% for lipase, 53 and 60% for amylase" Order ALL the reference details at left...
7.	Secretin FDA Link 04/01/1993 - "These results indicate that secretin stimulation provides useful information in the diagnosis of the etiology of pancreatic cyst by endoscopic ultrasonography." 04/01/1993 - "Morphological changes of small pancreatic cysts in response to secretin stimulation" 04/01/1984 - "In a patient with a large pancreatic cyst communicating with the main pancreatic duct, pancreatic DMO concentration after single rapid injection of secretin inversely correlated with the flow rate, while its output depended directly on the rate" 07/01/1955 - "Secretin in examination of drained pancreatic cysts; comparative study of intravenous, intramuscular and rectal administration.]" Order ALL the reference details at left...
8.	MucinsIBA 05/01/2007 - "CONCLUSIONS: With pancreatic cyst fluid analysis, the strongest predictor of mucinous neoplasia is the presence of identifiable mucin, followed by a CEA level greater than 300 ng/mL. The workup of cystic lesions of the pancreas should include chemical analysis for the CEA level and cytological examination with particular attention to extracellular mucin." 03/01/1997 - "The author performed a new operative procedure in 2 patients with mucin-producing pancreatic cysts that included total resection of the head of the pancreas with careful regard to its vasculature" 08/01/2004 - "In conclusion, cyst fluid analysis for cytology, mucin staining, CEA, and amylase levels are useful in the differential diagnosis of pancreatic cysts." Order ALL the reference details at left...
9.	Carcinoembryonic AntigenIBA 10/01/2005 - "METHODS: Endoscopic ultrasound-guided pancreatic cyst aspirates were prospectively collected during a period of 19 months and studied for cytology, carcinoembryonic antigen level, and molecular analysis" 07/01/1991 - "The contents obtained by fine needle aspiration (FNA) from 41 pancreatic cysts in 32 patients were studied cytologically and assayed for amylase and carcinoembryonic antigen (CEA) levels, which have been shown to discriminate pancreatic pseudocysts from mucinous cystic neoplasms and necrotic cystic carcinomas" 01/01/1993 - "In an attempt to develop new preoperative diagnostic criteria to assist in decisions regarding therapy, the authors have performed cyst fluid analysis for tumor markers (carcinoembryonic antigen: CEA, CA 125, and CA 19.9), amylase content, amylase isoenzymes, relative viscosity, and cytology on 26 pancreatic cysts" Order ALL the reference details at left...
10.	Pancreatic Elastase (Elastase)IBA 05/01/1986 - "In contrast, the levels of elastase 1 were significantly lower in patients with malignant cysts than in those with benign pancreatic cysts" 05/01/1986 - "The serum CA 19-9 was most useful, however, to distinguish an individual patient with malignant cysts of the pancreas from those with benign pancreatic cyst, since there were no significant differences between the levels of serum CEA and elastase 1 in patients with malignant and benign pancreatic cysts" 01/01/1989 - "Among the patients with chronic pancreatitis, either in painful relapse (N = 19) or with pancreatic cysts (N = 15), the respective percentages of enzymes elevations were: 79 and 80% for elastase 1, 68 and 67% for trypsinogen, 63 and 73% for pancreatic isoamylase, 58 and 60% for lipase, 53 and 60% for amylase" Order ALL the reference details at left...

Therapies and Procedures

1.	Laparotomy 01/08/1982 - "Laparotomy with removal of the pancreatic cysts and abdominal drainage led to complete recovery" 06/01/1987 - "Laparotomy demonstrated an irregular black pancreatic cyst, and histological examination showed atypical spindle shaped cells with brown to black pigmentation, compatible with malignant melanoma" 03/20/1975 - "Paracentesis abdominis or drainage of the fluid during exploratory laparotomy, permits one to obtain in certain cases, a cure of the ascites, but surgical drainage by an anastomosis between the pancreatic cyst and the digestive tract (pancreatico-digestive anastomosis), has the advantage of ensuring treatment of the ascites and of the responsible pancreatic disease." 07/01/1988 - "In the early postoperative period (within 30 days), laparotomy was required for pancreatitis (one), perforated peptic ulcer (two), cholecystectomy (one), pancreatic cyst (one) and appendicitis (one)" 01/17/1980 - "Subsequent studies of the patient's insulin (fortuitously obtained from his pancreas during a laparotomy for a pancreatic cyst) have confirmed this conclusion" Order ALL the reference details at left...
2.	Pancreatectomy 03/01/2006 - "Total excision with distal pancreatectomy and splenic preservation are advised for distal pancreatic cysts." 10/01/1999 - "Two patients required distal pancreatectomy because of their pancreatic pathology, 2 cystgastrostomies for persistence of the pseudocyst, and 1 external drainage of an infected pancreatic cyst" 01/01/1997 - "In the absence of pancreatic cyst, mass, or localized ductal abnormality, total pancreatectomy is the only treatment that can completely remove the risk of malignant degeneration of apparently benign, mucus-secreting pancreatic ductal enlargement" 01/19/2005 - "Among them one case with pancreatic head cyst and 4 cases of distal pancreatic cyst underwent simple laparoscopic cyst resection and one case of distal pancreatic cyst underwent laparoscopic distal pancreatectomy with resection of the spleen" 02/01/1984 - "A patient with a pancreatic cystadenocarcinoma was treated initially for a false pancreatic cyst by means of a Y loop, and then by total pancreatectomy three weeks later" Order ALL the reference details at left...
3.	Jejunostomy 12/01/2003 - "Laparoscopic Roux-en-Y pancreatic cyst-jejunostomy." 07/01/1998 - "The pancreatic cyst was drained by means of a mesocolic Roux-loop cysto-jejunostomy." 11/01/1955 - "Cysto-jejunostomy on a Y defunctionalized loop for pseudo-pancreatic cyst; technic of intracystic tampons.]" 04/01/1996 - "Of the two unsuccessful insertions, one proceeded to longitudinal pancreato-jejunostomy and in the other a stent was inserted at distal pancreatic cyst-jejunostomy" 08/01/2001 - "The operations included 53 colon and/or small bowel resections (54.1%), 24 fundoplications (24.5%), 12 gastric resections (12.2%), 3 splenectomies, 2 pancreatectomies, 1 adrenalectomy, 1 bilateral salpingo-oopherectomy, 1 pancreatic cyst-jejunostomy, and 1 vagotomy with gastrojejunostomy" Order ALL the reference details at left...
4.	Pancreaticojejunostomy 03/01/1993 - "In chronic pancreatitis, complicated also, preference was given to organ-preserving interventions, primarily to draining operations, which preserve more fully pancreatic exocrine and endocrine functions: longitudinal pancreatojejunostomy was conducted in 106 patients, internal drainage of pancreatic cysts in 184, and occlusion of external pancreatic cysts in 70 patients" 03/01/1977 - "Two patients with pancreatic cyst were treated by cystojejunostomy, two others with pancreaticolithiasis by pancreaticojejunostomy (side to side), and pancreato-duodenectomy was done in one patient with cancer of the duodenal papilla and in one patient with cancer of the intrapancreatic bile duct" 12/01/1947 - "Pancreatic fistula following surgery of pancreatic cyst; report of a case treated by pancreatojejunostomy." 06/01/1992 - "Pancreaticojejunostomy and resection of pancreatic cyst were carried out for repeated episodes of abdominal pain under the diagnosis of chronic pancreatitis" Order ALL the reference details at left...
5.	Stents 01/01/2008 - "For localizing diagnosis of these small and multiple pancreatic cysts, we placed an endoscopic pancreatic stent (EPS), and MDCT with injection of CO2 via EPS was examined for the virtual CO2 pancreatography, consisting of OsiriX software system employing 3D virtual anatomic reconstruction with CO2 gas as a negative contrast agent" 04/01/1996 - "Of the two unsuccessful insertions, one proceeded to longitudinal pancreato-jejunostomy and in the other a stent was inserted at distal pancreatic cyst-jejunostomy" 03/01/1990 - "The authors also worked out recommendations for a choice of instruments for prolonged external transcutaneous drainage of pancreatic cysts and abscesses, cleansing of the cavity and its sclerosing, inoperative cystogastrostomy between a cyst and a stomach stent." Order ALL the reference details at left...

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