Oxyphenbutazone

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211 relevant articles (5 outcomes, 20 trials/studies) found for this Drug

Description: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)

Also Known As:

Belmac Brand of Oxyphenbutazone; Diflamil; Novartis Ophthalmics Brand of Oxyphenbutazone; Oxyphenylbutazone; Tanderil; Hydroxyphenylbutazone; 3,5-Pyrazolidinedione, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl-

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 25

1-Ring Heterocyclic Compounds

4-hydroxy-oxyphenbutazone: 1

4-hydroxyphenylbutazone

kymalzone

Related Diseases

1.	Pain (Aches) 12/01/1964 - "[CLINICAL TRIALS WITH OXYPHENBUTAZONE IN CERVICAL AND LUMBAR PAIN SYNDROMES.]" 03/30/1960 - "The effect of oxyphenbutazone on pain related to vascular disease." 01/01/1978 - "The results of subjective assessments showed tha by Day 3 spontaneous pain had either completely resolved or markedly improved in all patients, and that diflunisal was significantly better than oxyphenbutazone on Days 1 and 3 in relieving pain on movement of the joint." 12/12/1983 - "Decrease in pain upon physical examination and in articular circumference was significantly greater with Bi-Profenid as compared with oxyphenbutazone. " 01/01/2004 - "The data collected in this pilot project revealed that pirfenidone was more effective (p < 0.025) than oxyphenbutazone in providing relief from arthritic pain. " Order ALL the reference details at left...
2.	Edema 04/20/1963 - "Trial of oxyphenbutazone for postoperative edema after bilateral herniorrhaphy." 08/01/2003 - "In EPP-induced edema IC(50) of DMPBD and oxyphenbutazone were 21 and 136nmol per ear, respectively. " 10/01/1966 - "It appeared from the results of these observations that Oxyphenbutazone is not effective in preventing postoperative edema in such operations or in promoting more rapid resolution of postoperative edema. " 11/01/1963 - "[TANDERIL IN OTORHINOLARYNGOLOGY WITH SPECIAL REFERENCE TO THE POSTOPERATIVE EDEMA.]" 09/01/1979 - "These changes are consistent with an inhibition of renal prostaglandin synthesis and could explain why oxyphenbutazone is reported to produce weight gain and edema when used clinically." Order ALL the reference details at left...
3.	Wounds and Injuries (Trauma) 02/01/1971 - "[Experiences with Tanderil in winter sport injuries]" 03/01/1968 - "Effect of oxyphenylbutazone on surgical wounds of horses." 02/01/1972 - "[Therapy and after care of superficial thrombophlebitis and of gynecological surgical wounds using Tanderil cream]" 01/01/1978 - "A double-blind randomized trial was carried out in 31 patients suffering from acute, minor ligamentous injuries to compare the efficacy of diflunisal in the relief of pain with that of oxyphenbutazone. " 05/14/1968 - "[Treatment of injuries with orally administered Varidase as compared to Chymoral and Tanderil]" Order ALL the reference details at left...
4.	Erythema 07/01/1978 - "It is superior to the comparable anti-inflammatory drugs in its effect on the inflammatory erythema of the skin; in its effect on the inflammatory edema of the skin, it stands between oxyphenbutazone and indomethacin." 01/01/1982 - "In regard to the topical activity, piroxicam antagonized significantly both the croton oil edema and the UV-erythema; against the latter experiment also ketoprofen exerted intense inhibition, whilst oxyphenbutazone proved inactive. " Order ALL the reference details at left...
5.	Eczema 07/01/1975 - "The efficacy of five per cent oxyphenbutazone cream in the treatment of venous eczema of the leg." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Indomethacin (Indometacin)
2.	Diflunisal (Dolobid)
3.	Ketoprofen (Orudis)
4.	pirfenidone
5.	Oxyphenbutazone
6.	Phenylbutazone (Butazolidin)
7.	Chloramphenicol (Chloromycetin)
8.	Sodium
9.	Prednisolone (Predate)
10.	Suppositories (Vaginal Suppositories)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Tooth Extraction (Tooth Extractions)

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