Oxyfedrine

A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

Also Known As:

Ildamen; Myofedrin; Oxifedrine; Oxiphedrin; Oxyphedrin; 1-Propanone, 3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(3-methoxyphenyl)-, (R-(R*,S*))-

Networked: 61 relevant articles (3 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Koike, Naoyoshi: 1 article (01/2020)
2.	Nagano, Osamu: 1 article (01/2020)
3.	Okazaki, Shogo: 1 article (01/2020)
4.	Otsuki, Yuji: 1 article (01/2020)
5.	Saya, Hideyuki: 1 article (01/2020)
6.	Suina, Kentaro: 1 article (01/2020)
7.	Yamasaki, Juntaro: 1 article (01/2020)

Related Diseases

1.	Angina Pectoris 07/01/1984 - "Effect of oxyfedrine on exercise performance and systolic time intervals in patients of angina pectoris." 12/01/1982 - "Clinical experiences with oxyfedrine in patients with angina pectoris." 10/01/1980 - "The severity degrees of the angina pectoris were diminished after the chronic application of l- and d,l-oxyfedrine. " 11/01/1972 - "Double-blind cross-over clinical trial of oxyfedrine in angina pectoris." 06/20/1971 - "[Ildamen in stenocardias]."
2.	Heart Diseases (Heart Disease) 04/01/1976 - "In feline experiments and 65 clinical cases of ischaemic heart disease the efficacy of a new beta-stimulating agetn -- Ildamen -- was studied, the obtained effect was compared to that of Euphillin. " 01/01/1991 - "Effect of intravenous oxyfedrine on exercise in patients with ischaemic heart disease." 04/01/1985 - "Oral oxyfedrine on left ventricular performance in patients of ischaemic heart disease." 01/01/1981 - "In order to assess the effects of oxyfedrine in ischaemic heart disease, echocardiographic evaluation of left ventricular function was performed 2,5,10,15 and 20 minutes after the intravenous administration of 12 mg oxyfedrine in 15 patients with coronary artery disease without angiographic abnormalities of left ventricular wall motion. " 09/01/1980 - "1 In a group of 23 patients with documented ischaemic heart disease who experienced angina pectoris, oral oxyfedrine (24 mg three times daily) was compared with isosorbide dinitrate (10 mg three times daily) and placebo in a double-blind double-crossover clinical trial. "
3.	Bundle-Branch Block (Fascicular Block) 05/01/1986 - "[Remission of left bundle-branch block with oxyfedrine. "
4.	Myocardial Infarction 06/01/1975 - "[Short-term and long-term studies of the therapeutic effectiveness of oxyphedrin in acute myocardial infarct]." 01/01/1985 - "Left ventricular function in acute myocardial infarction before and after oxyfedrine." 01/01/1981 - "[Effects of oxyfedrine on myocardial infarct size following coronary artery occlusion in rats (author's transl)]." 11/30/1978 - "[The effects of oxyfedrine on the hemodynamics of patients with acute myocardial infarction]." 10/01/1978 - "Effects of oxyfedrine on left ventricular function in patients several months after myocardial infarction."
5.	Coronary Artery Disease (Coronary Atherosclerosis) 12/01/1991 - "The results of this study indicate that in patients with coronary artery disease, intravenous oxyfedrine significantly increases regional myocardial blood flow, both in areas supplied by critically obstructed vessels and in areas supplied by normal or less severely narrowed coronary arteries." 12/01/1991 - "Effects of oxyfedrine on regional myocardial blood flow in patients with coronary artery disease." 05/01/1984 - "Oxyfedrine and cardiac inotropism in coronary artery disease." 01/01/1981 - "Echocardiographic evaluation of acute administration of oxyfedrine in patients with coronary artery disease." 12/01/1991 - "We assessed the effects of intravenous oxyfedrine on regional myocardial blood flow, using positron emission tomography (15-oxygen water), in six patients with chronic stable angina, positive exercise tests, and documented coronary artery disease. "

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3.	Verapamil (Calan)
4.	Nifedipine (Adalat)
5.	Strophanthins
6.	beta Adrenergic Receptors
7.	Molsidomine (SIN 10)
8.	Hydralazine (Apresoline)
9.	Nitroglycerin (Dynamite)
10.	Digoxin (Digitek)

Related Therapies and Procedures

1.	Therapeutics
2.	Intravenous Administration
3.	Intravenous Injections
4.	Injections