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Otitis

Inflammation of the ear, which may be marked by pain (EARACHE), fever, HEARING DISORDERS, and VERTIGO. Inflammation of the external ear is OTITIS EXTERNA; of the middle ear, OTITIS MEDIA; of the inner ear, LABYRINTHITIS.
Also Known As:
Ear Inflammation; Ear Inflammations; Inflammation, Ear; Inflammations, Ear; Otitides
Networked: 679 relevant articles (34 outcomes, 66 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Infection
2. Otitis Media
3. Sinusitis
4. Pneumonia (Pneumonitis)
5. Tonsillitis

Experts

1. Pichichero, Michael E: 9 articles (01/2015 - 11/2008)
2. Casey, Janet R: 7 articles (11/2013 - 11/2008)
3. Kaur, Ravinder: 3 articles (08/2012 - 01/2011)
4. Kwochka, Kenneth W: 3 articles (02/2009 - 06/2002)
5. Hillier, Andrew: 3 articles (02/2009 - 06/2002)
6. Cole, Lynette K: 3 articles (02/2009 - 04/2006)
7. Pichichero, M E: 2 articles (12/2015 - 10/2003)
8. Patel, Janak: 2 articles (07/2015 - 04/2013)
9. Jesic, Snezana: 2 articles (06/2014 - 06/2006)
10. Weese, J Scott: 2 articles (04/2014 - 08/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Otitis:
1. Anti-Bacterial Agents (Antibiotics)IBA
2. Ciprofloxacin (Cipro)FDA LinkGeneric
3. Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA
4. Ceftriaxone (Ceftriaxon)FDA LinkGeneric
08/01/2000 - "Ceftriaxone and otitis in children: new indication. "
01/01/1988 - "Therefore, single-dose ceftriaxone therapy cannot be suggested at present as routine therapy for acute otitis, although it may be considered a reasonable alternative in noncompliant patients."
09/01/1996 - "Pharmacokinetic study indicates that the values of the parameters in plasma after the administration of a dose of 100 mg/kg (peak level of total drug, 268 +/- 33 micrograms/ml; elimination half-life, 0.8 h; area under concentration-time curve, 488 micrograms.h.ml-1) were still suboptimal compared with the values of the parameters measured in pediatric patients after intravenous or intramuscular administration of a dose of 50 mg/kg. Our results indicate the efficacy of ceftriaxone against experimental cephalosporin-resistant pneumococcal otitis and provide a basis for the clinical use of single-dose ceftriaxone against pneumococcal otitis media."
01/01/1986 - "The efficacy of ceftriaxone, 1 g given intramuscularly once daily, was evaluated in 38 patients with pneumonia (n = 11), pulmonary empyema (n = 2), bronchitis (n = 4), tonsillitis (n = 9), sinusitis (n = 7), and otitis (n = 5). "
01/01/2010 - "To review current clinical evidence for the use of antibiotics in paediatric upper paediatric respiratory infections, repeated PubMed searches using the template algorithm -rhinosinusitis/otitis/ tonsillitis AND ()- with the settings: -Humans; English; All Child 0-18; Clinical trial; Review; Methanalysis; Guideline; Last 10 years- for the following comparators: antibiotic; amoxicillin; clavulanate; penicillin; cephalosporin; macrolide; erythromycin; rokitamycin; clindamycin; trimethoprim-sulfamethoxazole, cefopodoxime, cefdinir, cefuroxime, ceftriaxone. "
5. PolysaccharidesIBA
6. Immunoglobulin G (IgG)IBA
7. Penicillins (Penicillin)FDA Link
8. Immunoglobulins (Immunoglobulin)IBA
9. Amoxicillin (Wymox)FDA LinkGeneric
10. SulfamethoxazoleFDA LinkGeneric

Therapies and Procedures

1. Middle Ear Ventilation (Tympanostomy)
2. Osteopathic Manipulation
3. Topical Administration
4. Transplantation (Transplant Recipients)
5. Heterologous Transplantation (Xenotransplantation)