An abnormal hardening or increased density of bone tissue.
Also Known As:
Networked: 231 relevant articles (4 outcomes, 13 trials/studies) for this Disease, Comments

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasm Metastasis (Metastasis)
2. Fibrosis (Cirrhosis)
3. Prostatic Neoplasms (Prostate Cancer)
4. Osteolysis
5. Plasma Cell Leukemia


1. Tefferi, Ayalew: 5 articles (01/2006 - 01/2003)
2. Vainchenker, William: 4 articles (07/2007 - 04/2003)
3. Gelb, Bruce D: 3 articles (03/2009 - 11/2002)
4. Tulliez, Micheline: 3 articles (07/2007 - 04/2003)
5. Giraudier, Stéphane: 3 articles (07/2007 - 04/2003)
6. Whyte, Michael P: 2 articles (04/2015 - 01/2010)
7. Mumm, Steven: 2 articles (04/2015 - 01/2010)
8. Crosby, Andrew: 2 articles (09/2014 - 12/2013)
9. Wang, Jen C: 2 articles (12/2009 - 10/2004)
10. Hemavathy, Kirugaval: 2 articles (12/2009 - 10/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Osteosclerosis:
1. CollagenIBA
2. Reticulin (Reticular Fiber)IBA
09/19/1981 - "At bone biopsy, various aspects of panhyperplasia, increase in the reticular fibers, myeloid fibrosis and osteosclerosis were observed. "
08/01/2011 - "CT scanning displayed femoral cortical thickening, medulla canal narrowing and lumbar spine density increasing at day 150, meanwhile, HE staining and reticular fiber staining showed the fatty degeneration or vacuolization in liver, splenomegaly with megakaryocytic proliferation, femur bone marrow fibrosis and osteosclerosis. "
01/01/2000 - "A trephine biopsy showed a hypercellular bone marrow with a proliferation of abnormal megakaryocytes, mild reticulin fibrosis, and osteosclerosis, i.e., features of an early stage of idiopathic myelofibrosis. "
12/13/1975 - "One is characterized by bone marrow hyperplasia with reticulin myelofibrosis and is usually associated with large spleen and even in some cases with polycythemia but without radiologic bone lesions; the other is characterized by bone marrow of medium or hypoplasic constitution fibrosis, with or without osteosclerosis and with radiologic bone lesions of mode-rate or important extension (respectively 16.9 p. "
01/01/1989 - "This study was firstly aimed at testing correlations between histological features (amount of haematopoiesis, cytological aspects of megakaryocytes, density of reticulin and collagen fibres and degree of osteosclerosis) and laboratory data, as well as spleen size and duration of relevant prediagnostic symptoms. "
Order ALL the reference details at left...
3. DiphosphonatesIBA
4. Macrophage Colony-Stimulating FactorIBA
5. Parathyroid Hormone (Parathormone)IBA
6. Carbon MonoxideIBA
7. Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
8. Hexachlorobenzene (HCB)IBA
9. zoledronic acid (zoledronate)FDA Link
10. Bone Morphogenetic Protein ReceptorsIBA

Therapies and Procedures

1. Bone Marrow Transplantation (Transplantation, Bone Marrow)
2. Combination Drug Therapy (Combination Chemotherapy)
3. Osteotomy
4. Renal Dialysis (Hemodialysis)
5. Transplants (Transplant)

blog comments powered by Disqus
for Osteosclerosis,
Ranking and Evidence
*WARNING* This specific disease subtype has a relatively small number of significant evidence outcomes. You may proceed to order anyway, or go back to the search field and enter a more general type of the target illness. Once your report has been ordered, however, we can't refund the purchase.

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. Analytic charts allow you and your physicians to see at a glance the treatment options—including new, promising, off-label and experimental.
  • Free Updates for 1 Year
  • All 4 Outcomes
  • Top 200 Key Drugs and Biologics
  • Top 50 Key Therapies and Procedures
  • Detailed History Charts
  • Full Research Evidence References
  • Sample PDF Report on Psoriasis >>
Price:$24.95 USD & Delivery via PDF download
updates for 1 year
Research Interface PRO

Rapidly retrieve clinical outcome summaries for all evidence of drug efficacy against any disease in seconds. Click "Charts" to view graphs of relative efficacy of all drugs against any known disease. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time. Save hours of search and analysis time:
Price:$490.00 USD access via web interface
1 year subscription
Request Bulk Institution License Details >>