|4.||Infectious Arthritis (Septic Arthritis)
|1.||Lipsky, Benjamin A: 12 articles (05/2015 - 01/2004)|
|2.||Aragón-Sánchez, Javier: 11 articles (06/2015 - 03/2010)|
|3.||Zhang, Changqing: 10 articles (03/2014 - 04/2008)|
|4.||Calhoun, Jason H: 9 articles (05/2014 - 01/2002)|
|5.||Palestro, Christopher J: 8 articles (01/2015 - 06/2002)|
|6.||Senneville, Eric: 8 articles (04/2013 - 10/2004)|
|7.||Patel, Robin: 7 articles (08/2015 - 02/2006)|
|8.||Morbach, Henner: 7 articles (07/2014 - 12/2007)|
|9.||Embil, John M: 7 articles (04/2014 - 06/2006)|
|10.||Jia, Wei-Tao: 6 articles (12/2015 - 01/2010)|
|1.||Anti-Bacterial Agents (Antibiotics)IBA
10/01/1996 - "Most forms of acute osteomyelitis can be successfully treated with antibiotics, leading to complete healing without complications. "
01/01/1994 - "When the confidence that a patient has osteomyelitis is very high (> 90% probability), the improved outcomes associated with long-term antibiotics are achieved with little additional expense and with favorable cost-effectiveness ratios compared with those of the other strategies."
07/01/2004 - "Vertebral osteomyelitis can be successfully treated with spinal immobilization and parenteral antibiotics. "
12/01/2003 - "Acute osteomyelitis in the pediatric population as well as osteomyelitis caused by atypical Gram-positive organisms and some Gram-negative organisms may be treated successfully with oral antibiotics. "
07/01/2001 - "Screw loosening occurred in 2 patients and osteomyelitis was noted in another patient who was treated successfully with sequestrectomy and antibiotics. "
06/01/2012 - "The VBC is effective in treating chronic osteomyelitis of rabbit by providing a sustained release of vancomycin, in addition to stimulating bone regeneration, so it may be a promising biomaterial for treating chronic osteomyelitis."
03/01/2012 - "In addition, nHA is an effective and safe controlled-release vancomycin carrier for chronic osteomyelitis with bone defects that is induced by MRSA."
06/01/2008 - "We have evaluated the effect of internal and external osteosynthesis devices on the efficacy of vancomycin treatment in a rabbit model of methicillin-resistant Staphylococcus aureus (MRSA)-induced post-traumatic osteomyelitis. "
09/01/2005 - "The release of vancomycin from standard test cylinders was determined in vitro and the efficacy of the delivery system was measured in vivo using a rabbit model of chronic osteomyelitis. "
07/01/2010 - "We studied the DBM as the delivery vehicle for vancomycin in controlling the methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis as well as healing of the cavity simultaneously in an experimental study. "
|3.||Ciprofloxacin (Cipro)FDA LinkGeneric
08/01/1994 - "Ciprofloxacin may prove useful in the management of chronic osteomyelitis due to highly resistant gram-negative bacteria."
01/01/1994 - "Ciprofloxacin, a synthetic fluoroquinolone, is potent against a broad spectrum of bacteria associated with osteomyelitis. "
11/01/1986 - "Ciprofloxacin is effective against the main organisms causing osteomyelitis (staphylococcus aureus, pseudomonas aeruginosa) at low MIC. "
01/01/1990 - "Our data indicate that oral ciprofloxacin monotherapy is as safe and effective as conventional parenteral therapy in cases of osteomyelitis caused by susceptible organisms."
04/27/1987 - "Oral ciprofloxacin was an effective and safe therapy in patients with chronic contiguous osteomyelitis due to aerobic gram-negative bacilli."
|4.||Polymethyl Methacrylate (Sol)IBA
04/01/2015 - "In this study, we investigate the efficacy of physician-directed antibiotic-impregnated PMMA spacers in achieving remission of chronic tibial osteomyelitis. "
03/01/2000 - "Antibiotic-impregnated polymethylmethacrylate (PMMA) beads have improved the outcome of osteomyelitis treatment in both experimental models and clinical trials. "
08/01/2012 - "Efficacy of antibiotic-impregnated polymethylmethacrylate beads in a rhesus macaque (Macaca mulatta) with osteomyelitis."
01/01/2015 - "Randomized clinical trials need to be performed in order to determine whether bioactive glass would be able to replace the current golden standard of autologous bone usage or with the use of antibiotic containing PMMA beads (in the case of osteomyelitis). "
12/01/2013 - "In three children there was a stage I according to Stutz and Gächter, in thirteen a stage II and in four patients a stage III. Because of a concomitant femoral neck osteomyelitis in three cases and an osteomyelitis of the os pubis in a single patient, PMMA mini chains were locally administered. "
|5.||Rifampin (Rifampicin)FDA LinkGeneric
10/01/2012 - "The composite with 50 wt% of β-TCP showed the most promising rifampicin release profile and it also showed activity against a common osteomyelitis causing bacteria Pseudomonas aeruginosa. "
10/01/2012 - "Processing and sustained in vitro release of rifampicin containing composites to enhance the treatment of osteomyelitis."
06/01/1990 - "Quinolone-rifampin combination regimens may offer a nonparenteral option for the treatment of chronic osteomyelitis caused by methicillin-resistant S. "
10/01/1985 - "Thirteen patients with chronic osteomyelitis, treated for 6 months with rifampin, had serial 99mTc phosphate and 67Ga scans to determine their value in assessing response to treatment. "
01/01/1984 - "Osteomyelitis due to gram-positive organisms and to Haemophilus can be treated with rifampicin in combination with a second antibiotic, depending on the minimum inhibitory concentration of the infecting organism(s)."
07/01/2013 - "This analysis suggests that daptomycin is an effective and well-tolerated treatment option for osteomyelitis and highlights the importance of optimal surgical intervention and appropriate microbiological diagnosis for clinical outcomes."
09/01/2015 - "While adult studies suggest intravenous (IV) daptomycin may by beneficial for the treatment of MRSA osteomyelitis, it is not Food and Drug Administration approved for use in pediatrics, and minimal data are available related to its use in this population. "
09/01/2015 - "While daptomycin was effective in this patient, additional research is needed to determine the true safety and efficacy of this drug for treatment of osteomyelitis caused by MRSA in pediatric patients. "
01/01/2012 - "Daptomycin appears to be an effective therapeutic choice with an acceptable safety profile in the management of osteomyelitis that does not involve hardware."
08/01/2009 - "Safety and efficacy of daptomycin in the treatment of osteomyelitis: results from the CORE Registry."
|7.||Gentamicins (Gentamicin)FDA LinkGeneric
04/01/2012 - "Implant 20% that was capable to release gentamicin sulfate over a period of four weeks without marked burst effect could be used as a more suitable biodegradable delivery system for the local management of chronic osteomyelitis."
06/01/2005 - "This study demonstrates the efficacy of hLF1-11 incorporated into Ca-P bone cement as a possible therapeutic strategy for the treatment of osteomyelitis, showing efficacy comparable to that of gentamicin. "
01/01/2015 - "Here we propose polymeric nanoparticles as locally applied gentamicin delivery system useful in osteomyelitis therapy. "
12/01/2014 - "The nails served as gentamicin sulfate (GS) carrier - an antibiotic commonly used in the treatment of osteomyelitis. "
07/01/2013 - "The results indicate that the gentamicin-loaded borate bioactive glass implant, combining sustained drug release with the ability to support new bone formation, could provide a method for treating osteomyelitis induced by Gram-negative bacilli."
03/01/2010 - "The results indicate that TBGC pellets are effective in treating chronic osteomyelitis by providing a sustained release of teicoplanin, in addition to participating in bone regeneration."
09/01/1994 - "In open trials, teicoplanin has been found effective in home therapy of osteomyelitis but, as with other agents, prolonged dosage can be associated with adverse effects. "
02/01/2002 - "We performed a pilot study to assess the safety and efficacy of three-times weekly teicoplanin in the treatment of methicillin-resistant (MR) acute staphylococcal osteomyelitis. "
08/01/2010 - "The results indicate that the teicoplanin-loaded borate bioactive glass implant, combining sustained drug release with the ability to support new bone ingrowth, could provide a method for treating chronic osteomyelitis."
08/01/2010 - "Implantation of the teicoplanin-loaded pellets in a rabbit tibia osteomyelitis model resulted in the detection of teicoplanin in the blood for about 9 days. "
10/01/1982 - "Hyperbaric oxygen (HBO) has been reported to be beneficial in the treatment of mandibular osteomyelitis; however, controlled laboratory studies have been limited to the long bones. "
09/01/1990 - "Mechanistically, hyperbaric oxygen (HBO) appears useful for the treatment of osteomyelitis. "
05/01/1989 - "Mechanistically, hyperbaric oxygen (HBO) appears useful for the treatment of osteomyelitis. "
02/01/2004 - "Although only a few studies have shown the effectiveness, hyperbaric oxygen (HBO) therapy has been used as an adjunct in the management of chronic osteomyelitis in many hospitals in Taiwan. "
09/01/1990 - "Hyperbaric oxygen management of chronic staphylococcal osteomyelitis of the temporal bone."
01/01/2007 - "Corpectomy followed by titanium cage-plate reconstruction and the placement of rhBMP-2 may be a safe and effective treatment for selected patients with vertebral osteomyelitis. "
04/20/2007 - "To assess the efficacy of titanium mesh cages in the treatment of active vertebral osteomyelitis. "
06/01/2009 - "The purpose of this study was to investigate the outcome of expandable titanium cage implantation in large defects caused by acute vertebral osteomyelitis. "
04/01/2002 - "No study has examined the use of titanium cages to reconstruct the anterior column of the spine with vertebral osteomyelitis. "
11/01/2011 - "Transomental titanium plates for sternal osteomyelitis in cardiac surgery."
11/01/2011 - "The debridement and VSD of cavitas medullaris is a very effective and safe treatment for chronic osteomyelitis of tibia."
10/01/2010 - "The combination of antibiotic therapy and surgical debridement is effective in the treatment of chronic suppurative osteomyelitis (CSO). "
01/01/2015 - "To investigate the early clinical efficacy of induced membrane technique for reconstruction of large bone defects after debridement in adults with chronic osteomyelitis of limbs. "
11/01/2011 - "In chronic osteomyelitis in adults, a post-debridement antibiotic therapy beyond six weeks, or an IV treatment longer than one week, did not show enhanced remission incidences. "
12/01/2010 - "The surgical principles of management of chronic osteomyelitis of metatarsal bone of the foot have remained unchanged, but the debridement tools and level of precision have improved. "
01/01/2008 - "Successful therapy for a patient with an infected ascending aortic graft and sternal osteomyelitis without graft removal."
01/01/1984 - "This improved versatility of bone imaging may have a role in the management of osteomyelitis or complicated fractures, or in assessing the viability of vascularized bone grafts."
11/01/2009 - "Radiologic studies were the most useful diagnostic tools in tracts related to dental pathology, infected implants/bone grafts, and chronic osteomyelitis. "
12/01/2015 - "Acute fractures, nonunions, and nonunions with bone defects or osteomyelitis often need bone graft to facilitate union. "
09/01/2015 - "The remaining 15 cases of osteomyelitis were under control, including 12 cases of bone transport achieved one stage bone union, 3 cases achieved bone union via bone graft from iliac bone. "
06/01/2011 - "We also found that the probability of amputation secondary to osteomyelitis among patients with diabetes is two times higher for men and three times higher for non-geriatric patients; combined surgical treatment was associated with a significant reduction (78%) of the probability of amputation."
03/01/2013 - "In a select group of Charcot neuroarthropathy patients with chronic osteomyelitis, trans-tibial amputation resulted in improvement in self-reported outcomes. "
03/01/2013 - "The hypothesis of this study is that self-reported outcomes of patients with non-reconstructable Charcot neuroarthropathy and chronic osteomyelitis improve after trans-tibial amputation. "
11/01/2012 - "The purpose of this study was to determine the rate of residual osteomyelitis after different foot amputations in diabetic patients with a standardized method of determining a clean bone margin. "
06/01/2011 - "This study aimed to compare the rates of amputation associated with two different treatment plans for osteomyelitis being utilized with a group of Puerto Ricans with diabetes. "
01/01/2010 - "The in vitro and in vivo studies had shown that the TCP–PLGA microspheres were effective for the treatment of chronic osteomyelitis in an animal experimental model. "
09/01/2007 - "The in vitro and in vivo studies had shown that the implanted SF loaded microspheres were found to be effective for the treatment of chronic osteomyelitis in an animal experimental model. "
06/01/2010 - "Generally, it can be concluded that the granules containing GM impregnated microspheres may be used effectively in the treatment of the chronic osteomyelitis."
04/01/2004 - "Effective treatment of osteomyelitis with biodegradable microspheres in a rabbit model."
01/01/2010 - "Sterile TCP–PLGA microspheres were implanted in the proximal tibia of rats with methicillin resistant Staphylococcus aureus (MRSA) osteomyelitis. "
|5.||Drug Therapy (Chemotherapy)
08/01/2005 - "Despite the drug resistance that infecting organisms demonstrated in this series, a regimen of carefully selected extended antimicrobial-drug therapy appears effective for osteomyelitis caused by MDR Acinetobacter spp."
08/04/1992 - "The osteomyelitis was cured by surgery and chemotherapy. "
08/01/2015 - "Photodynamic Antimicrobial Chemotherapy (PACT) in osteomyelitis induced by Staphylococcus aureus: Microbiological and histological study."
01/01/2015 - "Adequate duration of anti-mycobacterial chemotherapy together with regular monitoring with blood and imaging tests are key factors determining the recovery outcome in patients with NTM osteomyelitis. "
11/01/2013 - "Here, we present a case of HNC treated with combined (cytotoxic) chemotherapy and radiation therapy (CCRT) complicated by ORN and osteomyelitis of the sternoclavicular complex involving large segments of both clavicles, the sternum, and the trachea. "