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Osteitis Deformans (Paget's Disease of Bone)

A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass. The resultant architecture of the bone assumes a mosaic pattern in which the fibers take on a haphazard pattern instead of the normal parallel symmetry.
Also Known As:
Paget's Disease of Bone; Paget Disease of Bone; Paget Disease, Bone; Pagets Disease, Bone
Networked: 661 relevant articles (56 outcomes, 62 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Bone Resorption
2. Osteoporosis
3. Neoplasm Metastasis (Metastasis)
4. Hypercalcemia (Milk Alkali Syndrome)
5. Neoplasms (Cancer)

Experts

1. Kimonis, Virginia E: 20 articles (05/2015 - 03/2002)
2. Nalbandian, Angèle: 12 articles (05/2015 - 01/2010)
3. Ralston, Stuart H: 12 articles (07/2014 - 10/2002)
4. Layfield, Robert: 11 articles (07/2014 - 09/2003)
5. Searle, Mark S: 8 articles (07/2014 - 09/2003)
6. Llewellyn, Katrina J: 7 articles (05/2015 - 01/2012)
7. Vesa, Jouni: 6 articles (05/2015 - 01/2010)
8. Nguyen, Christopher: 6 articles (01/2015 - 11/2011)
9. Devogelaer, Jean-Pierre: 6 articles (03/2014 - 01/2002)
10. Walsh, John P: 6 articles (08/2013 - 02/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Osteitis Deformans:
1. DiphosphonatesIBA
2. pamidronate (APD)FDA LinkGeneric
3. Etidronic Acid (HEDP)FDA LinkGeneric
4. zoledronic acid (zoledronate)FDA Link
5. risedronic acid (risedronate)FDA LinkGeneric
6. Calcitonin (Calcitonin, Eel)FDA LinkGeneric
7. Alendronate (Alendronate Sodium)FDA LinkGeneric
8. tiludronic acid (tiludronate)FDA Link
9. PlicamycinFDA Link
10. 6- amino- 1- hydroxyhexane- 1,1- diphosphonateIBA

Therapies and Procedures

1. Intravenous Infusions
2. Aftercare (After-Treatment)
3. Arthroplasty
4. Retreatment
5. Radiotherapy