Psittacosis (Ornithosis)

Infection with CHLAMYDOPHILA PSITTACI (formerly Chlamydia psittaci), transmitted to humans by inhalation of dust-borne contaminated nasal secretions or excreta of infected BIRDS. This infection results in a febrile illness characterized by PNEUMONITIS and systemic manifestations.

Also Known As:

Networked: 450 relevant articles (14 outcomes, 37 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Infections
2.	Trachoma
3.	Q Fever (Fever, Q)
4.	Pneumonia (Pneumonitis)
5.	Mycoplasma Pneumonia

Experts

1.	Vanrompay, Daisy: 3 articles (01/2018 - 01/2008)
2.	Gacouin, A: 2 articles (03/2019 - 10/2012)
3.	Jouneau, S: 2 articles (03/2019 - 10/2012)
4.	Letheulle, J: 2 articles (03/2019 - 10/2012)
5.	Braeckman, Lutgart: 2 articles (03/2009 - 01/2008)
6.	Duim, Birgitta: 2 articles (01/2008 - 12/2006)
7.	Pannekoek, Yvonne: 2 articles (01/2008 - 12/2006)
8.	Hu, Pengzhi: 1 article (01/2022)
9.	Li, Xiaoying: 1 article (01/2022)
10.	Liang, Jianping: 1 article (01/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Psittacosis:

1.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/1961 - "A cytochemical test for detection of antibiotics effective against psittacosis virus." 11/01/2021 - "The mNGS technology can early detect of psittacosis, reduce unnecessary use of antibiotics and short the course of the disease." 01/01/2018 - "Our current paper underlines the need for a broader implementation of PCR for early diagnosis of human psittacosis and thus early initiation of correct antibiotic treatment with reduction of morbidity and mortality." 01/01/1996 - "Ornithosis is still a life-threatening illness unless diagnosed early and adequately treated with antibiotics. " 09/01/1971 - "Control of contamination in psittacosis specimens by antibiotics."
2.	AntigensIBA 01/01/1957 - "Ornithosis; a study of virus and antigen." 01/01/1957 - "Studies on the ornithosis-related antigen from Bacterium anitratum; Bacterium anitratum and its ability to produce the ornithosis-related antigen." 04/01/1994 - "We propose that, in those laboratories routinely using the CF test, sera found to be positive for ornithosis antigen should be further tested by the MIF in order to clarify, both from an epidemiologic and clinical perspective, whether these patients are also serologically positive for C. " 08/01/1981 - "[Preparation of CF and HA antigens for serological diagnosis of Chlamydia psittacosis and serological survey among inhabitants in Aichi prefecture (author's transl)]." 03/01/1980 - "Species-specific antigens of three ornithosis strains of varying origin were isolated. "
3.	Penicillins (Penicillin)FDA Link 01/01/1970 - "[A penicillin resistant strain of the agent of ornithosis and its biological properties]." 05/01/1961 - "I. The effect of penicillin on psittacosis virus and Rickettsia burneti in tissue culture]." 08/13/1949 - "A case of psittacosis treated with penicillin." 03/01/1949 - "A number of recent reports in the literature have told of cure of psittacosis in man following enormous doses of penicillin in the early stages of the disease. " 03/01/1949 - "Human psittacosis cured by penicillin therapy."
4.	Chlortetracycline (Aureomycin)FDA Link 11/01/1949 - "A small number of cases of psittacosis appear to have responded favorably to aureomycin. " 10/15/1966 - "[Studies of parrots, parakeets and their excrement to demonstrate the presence of the causative agent of psittacosis following treatment of the birds with chlortetracycline]." 05/01/1978 - "[Possible sources of error in the determination of chlortetracycline in the blood and feces with the scope of state psittacosis control]." 07/22/1961 - "The effect of chlortetracycline on Australian parrots naturally infected with psittacosis." 01/01/1959 - "The effect of chlortetracycline on the immunological response of turkeys infected with ornithosis."
5.	Tetracycline (Achromycin)FDA LinkGeneric 12/01/1994 - "After the official confirmation of psittacosis in a collection of psittacine birds a total of 40 of them died during treatment with tetracycline. " 01/01/1991 - "If, however, ornithosis is suspected the recommended drug has been tetracycline. " 03/01/1966 - "[The development of cytoplasmic inclusions of ornithosis and trachoma viruses in cell cultures under the influence of tetracycline]." 01/01/1959 - " reviewing the distribution of human infection, describing the methods of diagnosing the infection in man and birds, and outlining briefly the mechanism of immunity, the author proceeds to the question of therapy with tetracycline compounds, which have proved effective for the treatment of human psittacosis provided that they are administered soon enough and over a sufficiently long period. " 10/01/1956 - "The influence of tetracycline compounds on the development of antibodies in psittacosis."
6.	Doxycycline (Periostat)FDA LinkGeneric 10/01/2022 - "Due to her contact with birds and CT findings which were suggestive of psittacosis, she was started on doxycycline and her condition improved thereafter. " 01/01/2013 - "Application of doxycycline in the described therapy regimen proved successful for the treatment of ornithosis. " 03/01/1979 - "[Attempts at prevention and therapy of psittacosis using doxycycline in parrots and parakeets]." 01/01/1987 - "Successful treatment by doxycycline of endocarditis caused by ornithosis." 01/01/2013 - "In the scope of a field study, 13 pigeon flocks with clinically manifest ornithosis were treated over a period of 25 days with a novel doxycycline formulation via drinking water. "
7.	VancomycinFDA LinkGeneric 01/01/1967 - "Effect of vancomycin on the growth of psittacosis-trachoma agents cultivated in eggs and cell culture." 01/01/1967 - "The antibiotic vancomycin was effective in preventing bacterial contamination during studies with psittacosis and trachoma (PT) agents. "
8.	Azithromycin (Zithromax)FDA LinkGeneric 08/01/2016 - "An interesting case of psittacosis is being reported here, which has been treated successfully with azithromycin. "
9.	Cephalosporins (Cephalosporin Antibiotics)IBA 01/01/1995 - "Of 135 patients with pneumonia, 68% were completely cured in the A + M group, and 65% in the cephalosporin group, the main reasons for treatment failure being Mycoplasma pneumonia or ornithosis. "
10.	Complement System Proteins (Complement)IBA 08/01/1966 - "[Studies on the epidemiology of ornithosis of the population in the Essen area on the basis of antibody determination with the complement fixation test]." 06/01/1965 - "[Serologic studies with complement binding reaction of ornithosis in a rural area]." 09/01/2006 - "He had a history of exposure to parakeets, and psittacosis was diagnosed based on the elevated serum complement fixation titer against Chlamydia psittaci. " 11/21/1998 - "The diagnosis 'psittacosis' was established on clinical grounds and confirmed serologically (complement fixation test). " 10/01/1994 - "Utility of complement fixation and microimmunofluorescence assays for detecting serologic responses in patients with clinically diagnosed psittacosis."

Therapies and Procedures

1.	Therapeutics 01/01/1984 - "[Further studies on improving oral psittacosis prevention and therapy in small parrots and various medium-size parakeets]." 09/05/1981 - "[Prophylaxis and therapy of psittacosis in the canary-winged parakeet (Brotogeris versicolorus chiriri (author's transl)]." 11/05/1979 - "[Psittacosis therapy and prophylaxis in lovebirds, cockatiels and other problem birds]." 06/15/1950 - "[A new psittacosis epidemic and effective therapy]." 08/01/1970 - "[Epidemiology, chemoprophylaxis and therapy of psittacosis. "
2.	Extracorporeal Membrane Oxygenation 10/01/2004 - "The second patient had psittacosis and received venovenous ECMO for respiratory failure. " 10/01/2023 - "Successful treatment of near-fatal pulmonary embolism and cardiac arrest in an adult patient with fulminant psittacosis-induced severe acute respiratory distress syndrome after veno-venous extracorporeal membrane oxygenation rescue: A case report and follow-up." 10/01/2023 - "Veno-venous extracorporeal membrane oxygenation (ECMO) was successfully performed for the rescue of an adult patient with severe acute respiratory distress syndrome (ARDS) induced by fulminant psittacosis, and then a near-fatal pulmonary embolism (PE) and cardiac arrest (CA) of the same patient was cured through catheter-directed thrombolysis. "
3.	Catheters 10/01/2023 - "Veno-venous extracorporeal membrane oxygenation (ECMO) was successfully performed for the rescue of an adult patient with severe acute respiratory distress syndrome (ARDS) induced by fulminant psittacosis, and then a near-fatal pulmonary embolism (PE) and cardiac arrest (CA) of the same patient was cured through catheter-directed thrombolysis. "
4.	Drug Therapy (Chemotherapy) 11/01/1968 - "Control of psittacosis by group chemotherapy of infected parrots." 05/01/1967 - "Observations on chemotherapy and immunization of birds against psittacosis." 06/01/1946 - "Studies on the chemotherapy of viruses in the psittacosis-lymphogranuloma venereum group; effect of certain chemotherapeutic agents on the growth of psittacosis virus (6BC strain) in tissues cultures and eggs." 05/01/1946 - "The chemotherapy of experimental psittacosis infection (strain 6BC)." 07/01/1946 - "Studies on the chemotherapy of viruses in the psittacosis-lymphogranuloma venereum group; effect of certain chemotherapeutic agents on psittacosis virus (6BC strain) infections in mice."
5.	Personal Protective Equipment 09/01/2013 - "Risk exposures for human ornithosis in a poultry processing plant modified by use of personal protective equipment: an analytical outbreak study." 04/18/2018 - "Fewer than 10% of students would use appropriate personal protective equipment in scenarios suggestive of Q fever or psittacosis. "