|1.||Sultana, Sarwat: 17 articles (02/2013 - 01/2003)|
|2.||Gilmour, Susan K: 9 articles (03/2014 - 01/2005)|
|3.||O'Brien, Thomas G: 9 articles (04/2009 - 04/2002)|
|4.||Hayes, Candace S: 8 articles (03/2014 - 01/2005)|
|5.||Gerner, Eugene W: 8 articles (01/2014 - 05/2002)|
|6.||Liu, Xian-Xi: 8 articles (11/2013 - 04/2003)|
|7.||Shantz, Lisa M: 8 articles (07/2012 - 04/2002)|
|8.||Feith, David J: 7 articles (01/2014 - 07/2003)|
|9.||Pegg, Anthony E: 7 articles (02/2012 - 04/2002)|
|10.||Khan, Naghma: 7 articles (11/2010 - 01/2003)|
12/01/1994 - "However, the ornithine decarboxylase (ODC) activity in the neoplasms was significantly greater than that of the non-neoplastic and control mucosae (P < 0.001). "
01/01/2005 - "To study the mechanism of this selective effect, we used the ornithine decarboxylase (ODC)/Ras double transgenic mouse model that develops spontaneous skin tumors due to over-expression of ODC and a v-Ha-ras transgene. "
11/01/2004 - "The aim of this study is to analyze MTAP and ornithine decarboxylase (ODC) expression in primary pancreatic tumor specimens. "
07/16/1999 - "The present study was designed to determine whether 2-AP could increase the biliary excretion of metabolites of AFB(1) in rats treated with this carcinogen and whether the agent could alter the activity of ornithine decarboxylase (ODC), which is considered to be associated with tumor promotion. "
06/01/1999 - "In this study, we investigated the effect of InsP6 on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ornithine decarboxylase (ODC) activity, an essential event in tumor promotion in HEL-30 cells, a murine keratinocyte cell line and SENCAR mouse skin. "
|2.||Skin Neoplasms (Skin Cancer)
09/01/2012 - "A significant reduction in the expression of ornithine decarboxylase, a key enzyme in the promotion stage of 2-stage skin cancer, in the plant-treated group was also observed. "
01/01/2010 - "Targeting ornithine decarboxylase for the prevention of nonmelanoma skin cancer in humans."
01/01/2003 - "In a second experiment, two groups each consisting of three CD(1) mice were used to assess the effect of pomegranate seed oil on TPA-stimulated ornithine decarboxylase (ODC) activity, an important event in skin cancer promotion. "
04/09/2009 - "The resulting novel two-drug combination therapy targeting cellular polyamine metabolism has shown exceptional efficacy against cutaneous squamous cell carcinomas (SCC) in a transgenic ornithine decarboxylase (ODC) mouse model of skin cancer. "
10/08/2010 - "Cytoplasmic accumulation of the RNA-binding protein HuR stabilizes the ornithine decarboxylase transcript in a murine nonmelanoma skin cancer model."
04/16/1987 - "Substrate specificity in the stimulation of intestinal ornithine decarboxylase activity by refeeding after starvation."
01/01/1987 - "Increasing the duration of maternal starvation resulted in a progressive increase in fetal brain ornithine decarboxylase. "
03/30/1982 - "Induction of ornithine decarboxylase in colon and liver by starvation and refeeding: a comparison of effects on total and holoenzyme."
11/15/1980 - "In conclusion, these findings indicate that the regulation of ornithine decarboxylase in many tissues is grossly impaired in diabetes and starvation. "
11/15/1980 - "Starvation for 48h decreased ornithine decarboxylase activity to very low values in tissues of both normal and diabetic rats. "
04/20/2002 - "In the present study, we found that BQ and LPA at concentrations of 25,50,75 mg/ml caused significant induction of hyperplasia, but only LPA caused an increase of epidermal ornithine decarboxylase (ODC). "
01/01/1994 - "Results from several studies have demonstrated that both ornithine decarboxylase (ODC) and DAO activity rise during adaptive hyperplasia seen after small bowel resection. "
06/01/1991 - "This study was undertaken to determine if inhibition of ornithine decarboxylase (ODC), the rate-limiting enzyme of polyamine synthesis, suppresses formation of intimal hyperplasia (IH) after arterial injury. "
09/01/2011 - "Induction of ornithine decarboxylase (ODC), a key enzyme in polyamine biosynthesis, in ODC transgenic skin stimulates epidermal proliferation but not hyperplasia, activates underlying stromal cells and promotes skin tumorigenesis following a single subthreshold dose of a carcinogen. "
09/01/1999 - "Type I diabetes is associated with jejunal mucosal hyperplasia, and administration of diflouromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), causes hypoplasia. "
|5.||Colonic Neoplasms (Colon Cancer)
11/30/1989 - "Our previous studies have shown that generalized polyamine depletion of the human colon cancer cell line COLO 320 by 2-difluoromethylornithine is associated with decreased transcription of the c-myc, c-fos, and ornithine decarboxylase (ODC) genes. "
07/15/2013 - "In human colon cancer specimens, the expression levels of MAT2A, ornithine decarboxylase (ODC), c-Jun and c-Fos are all elevated as compared to adjacent non-tumorous tissues. "
04/01/1994 - "Ornithine decarboxylase (ODC) is used as an early marker for colon cancer development. "
06/14/1991 - "Systemic alterations in ornithine decarboxylase activity caused by colon cancer in mice."
02/20/1991 - "Involvement of ornithine decarboxylase in the control of proliferation of the HT29 human colon cancer cell line. "
|5.||DNA (Deoxyribonucleic Acid)
|10.||ornithine decarboxylase antizyme
|3.||Drug Therapy (Chemotherapy)