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Ornithine Decarboxylase (Decarboxylase, Ornithine)

A pyridoxal-phosphate protein, believed to be the rate-limiting compound in the biosynthesis of polyamines. It catalyzes the decarboxylation of ornithine to form putrescine, which is then linked to a propylamine moiety of decarboxylated S-adenosylmethionine to form spermidine. EC 4.1.1.17.
Also Known As:
Decarboxylase, Ornithine; Carboxy-lyase, Ornithine; Ornithine Carboxy lyase; Ornithine Carboxy-lyase; L-Ornithine carboxy-lyase
Networked: 1520 relevant articles (24 outcomes, 129 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Sultana, Sarwat: 17 articles (02/2013 - 01/2003)
2. Gilmour, Susan K: 9 articles (03/2014 - 01/2005)
3. O'Brien, Thomas G: 9 articles (04/2009 - 04/2002)
4. Hayes, Candace S: 8 articles (03/2014 - 01/2005)
5. Gerner, Eugene W: 8 articles (01/2014 - 05/2002)
6. Liu, Xian-Xi: 8 articles (11/2013 - 04/2003)
7. Shantz, Lisa M: 8 articles (07/2012 - 04/2002)
8. Feith, David J: 7 articles (01/2014 - 07/2003)
9. Pegg, Anthony E: 7 articles (02/2012 - 04/2002)
10. Khan, Naghma: 7 articles (11/2010 - 01/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Skin Neoplasms (Skin Cancer)
3. Starvation
4. Hyperplasia
5. Colonic Neoplasms (Colon Cancer)

Related Drugs and Biologics

1. Eflornithine (Ornidyl)
2. Putrescine
3. Spermidine
4. Adenosylmethionine Decarboxylase
5. DNA (Deoxyribonucleic Acid)
6. anthracene
7. 9,10-Dimethyl-1,2-benzanthracene (DMBA)
8. Dinoprostone (PGE2)
9. Testosterone (Sustanon)
10. ornithine decarboxylase antizyme

Related Therapies and Procedures

1. Chemoprevention
2. Oral Administration
3. Drug Therapy (Chemotherapy)
4. Ovariectomy (Oophorectomy)
5. Hepatectomy