|1.||Alqasem, Mashael A: 1 article (04/2015)|
|2.||Kelly, Vincent P: 1 article (04/2015)|
|3.||Fergus, Claire: 1 article (04/2015)|
|4.||Barnes, Dominic: 1 article (04/2015)|
|5.||Vinayak, Manjula: 1 article (10/2005)|
|6.||Jaiswal, Yogesh K: 1 article (10/2005)|
|7.||Pathak, Chandramani: 1 article (10/2005)|
|8.||Ozawa, Y: 1 article (01/2001)|
|9.||Ishiwata, S: 1 article (01/2001)|
|10.||Itoh, K: 1 article (01/2001)|
01/01/2001 - "Although the levels of queuosine in cancer cells have been reported to be lower than those in normal cells, the expression levels of TGT remain to be determined. "
03/01/1984 - "Taking into account results of others indicating a possible involvement of the queuosine modification in differentiation of eukaryotic cells, we hypothesize that the queuosine defect may develop at an early stage of carcinogenesis (i.e., during the promotion phase) and be directly involved in abnormalities of mitochondria which have been observed frequently in transformed cells and tumors."
10/01/2005 - "Hypomodification of transfer RNA in cancer with respect to queuosine."
01/01/1983 - "Why is tumor tRNA hypomodified with respect to Q nucleoside?"
09/01/1994 - "There was a relationship between the levels of Q nucleoside and the tumor malignancy in the sense that the deficiency was greater in the highly malignant astrocytomas compared to meningiomas which are usually benign tumors. "
10/01/2005 - "In the present study queuosine modification of transfer RNA and TGTase activity is compared in normal, Dalton's lymphoma ascites transplanted (DLAT) cancerous and queuine treated DLAT cancerous mouse liver. "
09/10/1981 - "The nucleotide sequence of rat ascites hepatoma TRNAAsp was found to be the same as that of rat liver tRNAAsp, except that mannose-attached queuosine (manQ) present in the wobbling position of rat liver tRNAAsp was replaced by normal guanosine in rat ascites hepatoma tRNAAsp. "
01/22/1980 - "The enzyme catalyzes an exchange of queuine (the base of queuosine, Q) as well as its precursors and guanine for guanine originally located in the first position of the anticodon of "undermodified" tRNATyr, tRNAHis, tRNAAsn, and tRNAAsp from an Escherichia coli mutant or rat ascites hepatoma cells. "
|5.||Lung Neoplasms (Lung Cancer)
09/01/1992 - "These results, taken together with other previous studies, suggest that a decreased queuosine content of tRNA may be a general feature of neoplasms and may be useful for grading malignancy and perhaps also for the prediction of survival in human lung cancer."
09/01/1992 - "To elucidate the significance of tRNA hypomodified with queuine to the grade of malignancies in human solid tumors, the amount of tRNA having guanosine in place of queuosine was determined in human lung cancer and normal lung tissue, by exchanging the unmodified guanosine residue for [3H]guanine. "
|2.||aspartic acid- tRNA
|3.||Transfer RNA (tRNA)
|4.||queuine (Q base)
|5.||Amino Acyl Transfer RNA
|7.||Asp Transfer RNA