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Novobiocin (Streptonivicin)

An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
Also Known As:
Streptonivicin; Novobiocin Calcium; Novobiocin Sodium; Novobiocin, Monosodium Salt; Calcium, Novobiocin; Monosodium Salt Novobiocin; Sodium, Novobiocin; Crystallinic Acid; Benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl)-4-hydroxy-3-(3-methyl-2-butenyl)-
Networked: 267 relevant articles (19 outcomes, 18 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Blagg, Brian S J: 13 articles (09/2015 - 09/2005)
2. Donnelly, Alison C: 4 articles (12/2011 - 11/2008)
3. Dobrowsky, Rick T: 3 articles (09/2015 - 06/2012)
4. Vielhauer, George A: 3 articles (02/2015 - 01/2010)
5. Holzbeierlein, Jeffrey M: 3 articles (02/2015 - 01/2010)
6. Zhao, Huiping: 3 articles (08/2014 - 06/2011)
7. Holzbeierlein, Jeffrey: 3 articles (06/2011 - 03/2008)
8. Vielhauer, George: 3 articles (06/2011 - 03/2008)
9. Le Bras, Gaëlle: 3 articles (02/2009 - 11/2007)
10. Brion, Jean-Daniel: 3 articles (02/2009 - 11/2007)

Related Diseases

1. Infection
2. Sepsis (Septicemia)
3. Mastitis
4. Melanoma (Melanoma, Malignant)
5. Catheter-Related Infections

Related Drugs and Biologics

1. Rifampin (Rifampicin)
2. Penicillins (Penicillin)
3. pirlimycin
4. Tetracycline (Achromycin)
5. Interferon-alpha (Interferon Alfa)
6. Interleukin-2 (IL2)
7. Type II DNA Topoisomerases (Topoisomerase II)
8. Erythromycin (Erycette)
9. DNA (Deoxyribonucleic Acid)
10. Chloramphenicol (Chloromycetin)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Antibiotic Prophylaxis
3. Catheters
4. Hematopoietic Stem Cell Mobilization
5. Subcutaneous Injections