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Nomifensine (Nomifensin)

An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
Also Known As:
Nomifensin; Hoe-984; Linamiphen; Merital; Nomifensine Maleate; Nomifensine Maleate (1:1); Hoe 984; Hoe984; Maleate, Nomifensine; 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-
Networked: 178 relevant articles (5 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Tubić-Pavlović, Aleksandra: 1 article (06/2014)
2. Petrić, Aleksandra: 1 article (06/2014)
3. Radović-Janosević, Dragana: 1 article (06/2014)
4. Stefanović, Milan: 1 article (06/2014)
5. Wilson, S P: 1 article (08/2013)
6. Teixeira-Pinto, A: 1 article (08/2013)
7. Fadel, J: 1 article (08/2013)
8. Tavares, I: 1 article (08/2013)
9. Martins, I: 1 article (08/2013)
10. de Vries, M G: 1 article (08/2013)

Related Diseases

1. Depressive Disorder (Melancholia)
2. Parkinsonian Disorders (Parkinsonism)
3. Neurobehavioral Manifestations
4. Seizures (Seizure)
5. Epilepsy (Aura)

Related Drugs and Biologics

1. Dopamine (Intropin)
2. Maprotiline (Ludiomil)
3. Mianserin
4. clobazam (HR 376)
5. Amitriptyline (Elavil)
6. Imipramine (Janimine)
7. Nomifensine (Nomifensin)
8. Bupropion (Wellbutrin)
9. Antidepressive Agents (Antidepressants)
10. Clomipramine (Anafranil)

Related Therapies and Procedures

1. Induced Hypothermia
2. Oral Administration
3. Ligation
4. Induced Hyperthermia (Thermotherapy)
5. Analgesia