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Nogalamycin

An anthrocycline from a Streptomyces nogalater variant. It is a cytolytic antineoplastic that inhibits DNA-dependent RNA synthesis by binding to DNA.
Also Known As:
U-15167; U 15167; U15167; 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-14-carboxylic acid, 11-((6-deoxy-3-C-methyl-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy)-4-(dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3,5,8,10,13-pentahydroxy-6,13-dimethyl-9,16-dioxo-, methyl ester, (2R-(2alpha,3beta,4alpha,5beta,6alpha,11beta,13alpha,14alpha))-
Networked: 14 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Yakovleva, Lyudmila: 1 article (05/2004)
2. Jerina, Donald M: 1 article (05/2004)
3. Sayer, Jane M: 1 article (05/2004)
4. Shuman, Stewart: 1 article (05/2004)
5. Pirrung, Michael: 1 article (05/2004)
6. Handy, Christopher J: 1 article (05/2004)

Related Diseases

1. Breast Neoplasms (Breast Cancer)
2. Neoplasms (Cancer)
3. Leukemia
4. Experimental Melanoma
5. Leukemia L1210

Related Drugs and Biologics

1. Menogaril
2. Doxorubicin (Adriamycin)
3. DNA (Deoxyribonucleic Acid)
4. Daunorubicin (Cerubidine)
5. Mitomycin (Mitomycin-C)
6. Aclarubicin
7. Tubercidin
8. RNA (Ribonucleic Acid)
9. Mitoxantrone (Novantrone)
10. Methylcholanthrene

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Transplantation (Transplant Recipients)