|1.||Zhai, R Grace: 3 articles (01/2013 - 11/2006)|
|2.||McBurney, Michael W: 2 articles (12/2011 - 08/2005)|
|3.||Zhai, Qiwei: 2 articles (12/2011 - 08/2005)|
|4.||Beirowski, B: 2 articles (01/2007 - 12/2001)|
|5.||Coleman, M P: 2 articles (01/2007 - 12/2001)|
|6.||Magni, G: 2 articles (01/2007 - 12/2001)|
|7.||Conforti, L: 2 articles (01/2007 - 12/2001)|
|8.||Wang, Peng: 1 article (06/2015)|
|9.||Bao, Cuifen: 1 article (06/2015)|
|10.||Wei, Jia: 1 article (06/2015)|
12/31/2010 - "Overexpression of nicotinamide mononucleotide adenylyltransferase (Nmnat), a component of the slow Wallerian degeneration (Wld(s)) protein, protects axons from a variety of insults. "
05/13/2009 - "Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration."
01/01/2007 - "The slow Wallerian degeneration protein (Wld(S)), a fusion protein incorporating full-length nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1), delays axon degeneration caused by injury, toxins and genetic mutation. "
04/01/2003 - "We cross-bred these mice with the spontaneous mutant C57BL/Wld(s) typically showing protection from Wallerian degeneration because of fusion of the ubiquitination factor E4B (Ube4b) and nicotinamide mononucleotide adenylyltransferase (Nmnat) genes. "
12/01/2001 - "We identified the protective gene, which encodes an N-terminal fragment of ubiquitination factor E4B (Ube4b) fused to nicotinamide mononucleotide adenylyltransferase (Nmnat), and showed that it confers a dose-dependent block of Wallerian degeneration. "
|2.||Hepatocellular Carcinoma (Hepatoma)
01/01/1974 - "[Activity of NAD-pyrophosphorylase in the cell nuclei of normal liver and transplanted hepatoma]."
01/01/1985 - "NAD pyrophosphorylase activity was substantially deleted in the tiazofurin resistant leukemia lines, but was only significantly decreased in the hepatoma resistant line. "
01/01/1985 - "A comparison of the biochemical expression of resistance to tiazofurin in drug-induced resistant lines of hepatoma 3924A, leukemias L1210 and P388 revealed that the 3 lines expressed similar genetic alterations related to reduced TAD content, decreased NAD pyrophosphorylase activity and increased synthesis of guanylates from salvaging preformed guanine indicating that these 3 factors play an important role in the resistance to tiazofurin. "
02/01/1966 - "3. In the primary hepatomas the concentrations of both NAD and NADP fell drastically and the activities of NMN adenylyltransferase and NAD(+) kinase fell to about 50% of the control activities. "
02/01/1966 - "1. The oxidoreduction state and concentration of both NAD and NADP as well as the maximum potential activities of NMN adenylyltransferase and NAD(+) kinase have been measured in the livers of rats treated for 14-28 days with 4-dimethylamino-3'-methylazobenzene, 4-dimethylamino-4'-fluoroazobenzene, alpha-naphthyl isothiocyanate or ethionine and in primary hepatomas induced by 4-dimethylamino-3'-methylazobenzene. "
07/19/2013 - "The chromosomal region encoding the nuclear NAD(+) synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) is frequently deleted in human cancer. "
01/01/1983 - "Since these results suggested that the anabolite might be a dinucleotide with a phosphodiester linkage of the kind found in NAD, attempts were made to synthesize such an analogue from the 5'-monophosphate of thiazole nucleoside and ATP-Mg2+, using a purified preparation of NAD pyrophosphorylase; modest yields were obtained of a compound with chromatographic, spectral and enzyme-inhibitory properties identical to those of the material isolated from P388 tumor nodules. "
05/27/2011 - "Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1alpha pathway."
01/01/2013 - "Here, we show that the NAD synthase nicotinamide mononucleotide adenylyltransferase (Nmnat) functions endogenously to protect Drosophila class IV dendritic arborization (da) sensory neurons against hypoxia-induced dendritic damage. "
|5.||Leber Congenital Amaurosis
|3.||AMP-Activated Protein Kinases
|5.||Proteasome Endopeptidase Complex (Proteasome)
|6.||Ubiquitin-Activating Enzymes (Ubiquitin-Activating Enzyme)
|8.||Messenger RNA (mRNA)
|9.||Proteins (Proteins, Gene)