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Nicotinamide-Nucleotide Adenylyltransferase

An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals. EC 2.7.7.1.
Also Known As:
ATP-NMN Adenylyltransferase; ATP NMN Adenylyltransferase; Adenylyltransferase, ATP-NMN; Adenylyltransferase, NMN; Adenylyltransferase, Nicotinamide Mononucleotide; Adenylyltransferase, Nicotinamide-Nucleotide; Mononucleotide Adenylyltransferase, Nicotinamide; Nicotinamide Nucleotide Adenylyltransferase; Pyrophosphorylase, NAD; NAD Pyrophosphorylase; NMN Adenylyltransferase; Nicotinamide Mononucleotide Adenylyltransferase; ATP:nicotinamide-nucleotide adenylyltransferase
Networked: 25 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Zhai, R Grace: 3 articles (01/2013 - 11/2006)
2. McBurney, Michael W: 2 articles (12/2011 - 08/2005)
3. Zhai, Qiwei: 2 articles (12/2011 - 08/2005)
4. Beirowski, B: 2 articles (01/2007 - 12/2001)
5. Coleman, M P: 2 articles (01/2007 - 12/2001)
6. Magni, G: 2 articles (01/2007 - 12/2001)
7. Conforti, L: 2 articles (01/2007 - 12/2001)
8. Wang, Peng: 1 article (06/2015)
9. Bao, Cuifen: 1 article (06/2015)
10. Wei, Jia: 1 article (06/2015)

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Related Drugs and Biologics

1. NAD (NADH)
2. NAD+ synthase
3. AMP-Activated Protein Kinases
4. Alpha-Amanitin
5. Proteasome Endopeptidase Complex (Proteasome)
6. Ubiquitin-Activating Enzymes (Ubiquitin-Activating Enzyme)
7. Ubiquitin
8. Messenger RNA (mRNA)
9. Proteins (Proteins, Gene)
10. NADP (NADPH)