Nitrogen

An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.

Networked: 17767 relevant articles (612 outcomes, 1359 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Tsuchiya, Hiroyuki: 35 articles (02/2021 - 01/2003)
2.	Forchhammer, Karl: 24 articles (10/2022 - 11/2000)
3.	Wang, Wei: 23 articles (03/2022 - 07/2006)
4.	Klionsky, Daniel J: 19 articles (04/2022 - 02/2003)
5.	Zhang, Wei: 19 articles (01/2022 - 09/2004)
6.	Li, Yan: 18 articles (01/2022 - 10/2005)
7.	Hayashi, Katsuhiro: 17 articles (02/2021 - 11/2009)
8.	Yamamoto, Norio: 17 articles (02/2021 - 01/2003)
9.	Huang, Chi-Chang: 15 articles (06/2022 - 01/2015)
10.	Liu, Wei: 15 articles (06/2022 - 06/2011)

Related Diseases

1.	Body Weight (Weight, Body) 07/01/1988 - "Treatment of rats with recombinant human TNF initially causes a marked decrease in food intake, a loss of body weight, and a negative nitrogen balance. " 03/01/2005 - "There was a significant interaction between energy level and Dex such that the increase in body catabolism due to 50%E from CHO or FAT was reduced by approximately 50%, although the amount of body weight and nitrogen lost over 7 d was significantly greater with 50%E than with AE. AE+Dex induced a 60% increase in liver mass, whereas 50%E+Dex reduced the increase to 26%. " 11/01/1984 - "Nutritional status was improved (e.g., positive nitrogen balance was established); the patient absorbed nutrients better; and some lean body mass was restored, while total body weight decreased." 02/01/2014 - "Increased nitrogen application improved nitrogen contents of the plants and also the body weight of cereal aphids feeding on them. " 01/01/2022 - "The population reference intake for adults set by the European Food Safety Authority is 0.83 g/kg body weight (BW)/d based primarily on nitrogen balance studies, but the underlying data on health outcomes are outdated. "
2.	Neoplasms (Cancer) 03/01/1984 - "In this improved calibration technique total body nitrogen is more accurately measured, not only in normal subjects, but also in obese subjects and in patients with marked changes in hydration, such as cancer patients. " 07/01/1995 - "Seven of the 10 cancer patients were at or above 90% of ideal body weight, and they had a significant improvement in nitrogen balance (-1.46 +/- 0.99 vs. 0.60 +/- 1.03 g/day; P < 0.01). " 09/01/2023 - "After tumor resection, extracorporeal radiation therapy and the application of liquid nitrogen are still useful treatment options and neither of them is superior to the other." 04/01/2021 - "DTF invading the skull base is prone to recurrence, and liquid nitrogen treatment is considered to be effective in pediatric patients, who need cranioplasty with tumor-infiltrating autologous bone flaps." 07/01/2021 - "Biologic reconstruction using tumor-bearing bone autografts devitalized by liquid nitrogen or extracorporeal irradiation (oncological sterilization) is a safe and effective method in musculoskeletal surgery. "
3.	Starvation 01/01/2023 - "We further showed that this self-regulation mechanism could be widespread in other mycobacteria, which might be beneficial for those slow-growing mycobacteria to adapt to the nitrogen-starvation environments such as within human macrophages for M. " 07/01/2008 - "Nitrogen starvation also reduced significantly the strength of cell adhesion to the soil particles, except for Klebsiella sp. LBBMA 204-1. Two of the four strains showed significant reduction in cell surface hydrophobicity. " 01/01/2019 - "Relief from nitrogen starvation entails quick unexpected down-regulation of glycolytic/lipid metabolism genes in enological Saccharomyces cerevisiae." 05/01/2022 - "The improvement in relative abundance of the certain genera relating to denitrification was the main reason for the partial recovery of nitrogen removal after eliminating stress starvation. " 12/10/2015 - "In this work we investigated a novel, one-stage combined cultivation/fermentation strategy including inherently progressing nitrogen starvation conditions to generate improved microalgal biomass substrates. "
4.	Proteinuria 01/01/1993 - "Effect of proteinuria on renal interstitium: effect of products of nitrogen metabolism." 03/01/1948 - "Prolonged parenteral plasma produces hyperproteinemia and proteinuria in dogs and maintains nitrogen equilibrium and health." 03/30/2021 - "Treatment of NZB/W mice with lanraplenib improved overall survival, prevented the development of proteinuria, and reduced blood urea nitrogen concentrations. " 06/01/2010 - "Double-knockouts lived 47% longer, mice with 50% DDR1 lived 29% longer and showed improved renal function (reduction in proteinuria and blood urea nitrogen) compared to animals with 100% DDR1 expression. " 03/01/2022 - "Our aim was to study the effect of higher (1.2 g/kg/day) and lower (0.8 g/kg/day) protein intakes on nitrogen balance, body composition, glomerular filtration rate (GFR), and proteinuria in renal transplant recipients with low estimated GFR (eGFR) (15-44 mL/min/1.73 m2). "
5.	Fibrosis (Cirrhosis) 04/01/1985 - "The patients with cirrhosis had a significantly greater nitrogen balance than the control group (12.5 +/- 7.0 mmol/h versus 7.0 +/- 5.9 mmol/h; P less than 0.05). " 01/01/1985 - "There is considerable interest in providing nutritional supplements to patients with cirrhosis and PSE which would lead to improvement in nitrogen balance while improving or at least not worsening PSE. " 06/01/1951 - "Nitrogen balance studies in Laennec's cirrhosis of the liver." 02/01/1948 - "Further studies of nitrogen and fat metabolism in infants and children with fibrosis of the pancreas." 01/01/2020 - "In an observational before-and-after intervention study, the ureagenesis capacity was quantified by functional hepatic nitrogen clearance (FHNC) in 9 CHC patients with cirrhosis and 10 healthy volunteers. "

Related Drugs and Biologics

1.	Urea (Carbamide)
2.	Creatinine
3.	Proteins (Proteins, Gene)
4.	Oxygen (Dioxygen)
5.	Blood Glucose (Blood Sugar)
6.	Diphosphonates (Bisphosphonates)
7.	Albumins
8.	Amino Acids
9.	Glucose (Dextrose)
10.	Triglycerides (Triacylglycerol)

Related Therapies and Procedures

1.	Cryotherapy (Therapy, Cold)
2.	Therapeutics
3.	Cryosurgery
4.	Total Parenteral Nutrition
5.	Enteral Nutrition (Feeding, Tube)