Nikethamide

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51 relevant articles (1 outcomes, 2 trials/studies) found for this Bio-Agent

Description: A CENTRAL NERVOUS SYSTEM STIMULANT. It was formerly used in the treatment of barbiturate overdose but is now considered to be of no value for such purposes and may be dangerous. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1229)

Also Known As:

Coramin; Coramine; Cordiamine; Nicethamide; Nicotinic Diethylamide; Diethylamide, Nicotinic; Corethamid; Diethylnicotinamid; Nizethamid; 3-Pyridinecarboxamide, N,N-diethyl-

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 25

1-Ring Heterocyclic Compounds

Related Diseases

1.	Shock 02/01/1969 - "[Efficacy of using a combination of cordiamine with vitamin B 1 in posthemorrhagic shock]" 01/01/1955 - "[Association of desoxycorticosterone with coramine in the prevention of postoperative shock.]" 05/01/1974 - "[Comparative characteristics of cordiamine, corazole and bemegride in posthemorrhagic shock in experiments on dogs]" Order ALL the reference details at left...
2.	Seizures (Seizure) 01/04/1951 - "[Treatment of asthmatic seizures with nebulized 10% coramin suspension.]" 05/01/1960 - "[Metabolism of phosphorus compound and proteins in the brain in rats during excitation and convulsions produced by cordiamine.]" 02/01/1975 - "Mice pretreated with procaine, lidocaine, and tetracaine had a lower incidence of seizures when convulsive doses of either nikethamide or doxapram hydrochloride were given intraperitoneally. " 08/01/1970 - "When given alone in higher doses, chlorpromazine induced convulsions.3. The central stimulants bemegride and picrotoxin antagonized the loss of righting reflex produced by phenobarbitone, but nikethamide, caffeine and strychnine did not alter the depressant effects of phenobarbitone.4. On the basis of these and previous studies with intact white mice a tentative classification of drugs having generalized depressant and stimulant effects on the central nervous system was proposed and discussed." Order ALL the reference details at left...
3.	Pain (Aches) 06/01/1973 - "Modification of the analgesic action of pethidine and morphine by three opiate antagonists, a respiratory stimulant (doxapram) and an analeptic (nikethamide); a study using an experimental pain stimulus in man." Order ALL the reference details at left...
4.	Poisoning 03/01/1960 - "Nikethamide, nocotinamide and some related compounds in anticholinesterase poisoning." 10/01/1983 - "Therapies including absorption retardants, diuretics, reduction of urine pH, thermal support and treatment with phentolamine or nikethamide were given to groups showing these signs of poisoning. " 04/13/1950 - "[Amphetamine therapy of acute barbiturate poisoning; comparison of nicethamide and amphetamine therapy based on 193 cases.]" 12/01/1948 - "Coramine in barbiturate poisoning, comparison with picrotoxin; preliminary report." 07/01/1949 - "Treatment of intoxication by morphine and other hypnotics by intravenal injections of nikethamide [Hebrew Text]." Order ALL the reference details at left...
5.	Hyperbilirubinemia 09/28/1972 - "[Prevention of hyperbilirubinemia in premature infants using a combination of two enzyme inductors: phenobarbitol and nikethamide]" 01/01/1973 - "[Prevention of toxic hyperbilirubinemia in premature and mature newborn infants by use of an enzyme-inducing combination: phenobarbital-nikethamide]" 09/23/1972 - "[Prevention of transitory hyperbilirubinemia of the premature and mature newborn infants and of the hemolytic disease of the newborn by an enzyme induction combination: phenobarbital-nikethamide]" 04/01/1989 - "The effectiveness of phenobarbital, ziscorine, cordiamine and the combination of phenobarbital and pyrogenal was studied in 48 patients with non-conjugated hyperbilirubinemia. " 04/01/1989 - "[Effectiveness of phenobarbital, ziksorin and cordiamine in the treatment of non-conjugated hyperbilirubinemia]" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Thiamine (Aneurin)
2.	Phenobarbital (Luminal)
3.	Picrotoxin
4.	Morphine (MS Contin)
5.	Doxapram (Doxapram Hydrochloride)
6.	Bemegride
7.	Central Nervous System Stimulants
8.	Strychnine
9.	Meperidine (Pethidine)
10.	Chlorpromazine (Thorazine)

Related Therapies and Procedures

1.	Artificial Pneumothorax
2.	Injections
3.	Aftercare (After-Treatment)

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