|1.||Cerecetto, Hugo: 7 articles (06/2015 - 01/2008)|
|2.||González, Mercedes: 7 articles (06/2015 - 01/2008)|
|3.||Wilkinson, Shane R: 4 articles (04/2013 - 04/2008)|
|4.||Saulnier Sholler, Giselle L: 4 articles (05/2011 - 10/2006)|
|5.||Brard, Laurent: 4 articles (05/2011 - 03/2009)|
|6.||Urbina, Julio A: 4 articles (07/2010 - 01/2008)|
|7.||Read, Kevin D: 3 articles (09/2015 - 07/2010)|
|8.||Chappuis, François: 3 articles (01/2014 - 11/2010)|
|9.||Hall, Belinda S: 3 articles (04/2013 - 01/2011)|
|10.||Bot, Christopher: 3 articles (04/2013 - 01/2011)|
|1.||Chagas Disease (American Trypanosomiasis)
09/01/2013 - "In this work, we evaluated the parasitological efficacy of Nifurtimox treatment in 21 women with chronic Chagas disease from an area of endemicity in Chile who were treated according to current protocols. "
02/01/2012 - "[Efficacy of nifurtimox for the treatment of chronic Chagas disease]."
02/01/2012 - "Studies of chronic asymptomatic Chagas disease patients treated exclusively with nifurtimox were included in the analysis. "
04/01/2003 - "Nifurtimox has been used successfully in the treatment of American trypanosomiasis, or Chagas disease, but only in small studies or as a compassionate use treatment. "
01/01/2002 - "The aim of the present study was to study the trypanocidal activity of nanoparticles loaded with nifurtimox in comparison with the free drug against Trypanosoma cruzi, responsible for Chagas' disease. "
02/01/2012 - "To evaluate the efficacy of nifurtimox treatment in chronic asymptomatic Trypanosoma cruzi infection. "
07/01/1977 - "[Evaluation of the efficacy of nifurtimox in chronic human chagasic infection by using xenodiagnosis (author's transl)]."
04/01/2014 - "Toxic and therapeutic effects of Nifurtimox and Benznidazol on Trypanosoma cruzi ex vivo infection of human placental chorionic villi explants."
09/20/2013 - "brucei brucei infection in mice when used together with nifurtimox. "
02/01/2011 - "In fact, the loss of barrier integrity associated with trypanosome infection failed to change the distribution of [(3)H]nifurtimox to any significant extent, suggesting there is not an effective paracellular barrier for [(3)H]nifurtimox entry into the CNS. "
|3.||African Trypanosomiasis (Nagana)
04/01/2008 - "This potential for drug resistance by a simple mechanism has important implications, because nifurtimox is currently undergoing phase III clinical trials against African trypanosomiasis."
01/01/1977 - "Clinical trials with "nifurtimox" in African trypanosomiasis."
07/01/2002 - "A third drug, nifurtimox, is a cheap, orally administered drug not yet fully validated for use in human African trypanosomiasis. "
03/01/1984 - "[Clinical trial of nifurtimox in human African trypanosomiasis]."
02/01/2011 - "Nifurtimox, an antiparasitic drug, is used to treat American trypanosomiasis (Chagas disease) and has shown promise in treating central nervous system (CNS)-stage human African trypanosomiasis (HAT; sleeping sickness). "
03/01/2009 - "Therefore, further studies are warranted to develop nifurtimox as a promising new treatment for neuroblastoma."
10/01/2006 - "Nifurtimox shows promise as a potential new treatment for neuroblastoma and warrants further testing."
02/01/2011 - "RKS262 was identified by structural optimization of Nifurtimox which is currently undergoing phase II clinical trials to treat high-risk neuroblastoma. "
01/01/2011 - "A phase 1 study of nifurtimox in patients with relapsed/refractory neuroblastoma."
01/01/2015 - "Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma."
01/01/1992 - "DFMO is not very active in rhodesiense sleeping sickness and experience with nifurtimox in this form of trypanosomiasis is too limited to draw valid conclusions. "
10/01/1998 - "In the search for novel antitoxoplasmic agents, we evaluated the efficacy of nifurtimox (3-methyl-4[5'-nitrofurfurylidene-amino]-tetrahydroe-4H-1,4- thiazine-1,1-dioxide), an antiprotozoal drug effective against trypanosomiasis, in an experimental model of acute toxoplasmosis in mice. "
02/01/2007 - "We here discuss the use of current drugs against human and veterinary African trypanosomiasis, the prevalence, causes and mechanisms of drug resistance and new developments in trypanosomiasis therapy such as the introduction of nifurtimox and DB289."
02/01/2014 - "A significant improvement in the treatment of trypanosomiases has been achieved with the recent development of nifurtimox-eflornithine combination therapy (NECT). "
07/04/2009 - "Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial."
|5.||Melarsoprol (Mel B)
|9.||Suramin (Suramin Sodium)
|1.||Drug Therapy (Chemotherapy)