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Neutral Red

A vital dye used as an indicator and biological stain. Various adverse effects have been observed in biological systems.
Also Known As:
C.I. Basic Red 5; Nuclear Fast Red (Basic Dye); Red, Neutral; Red, Toluylene; Toluylene Red; 2,8-Phenazinediamine, N8,N8,3-trimethyl-, monohydrochloride
Networked: 245 relevant articles (5 outcomes, 25 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Onoue, Satomi: 8 articles (08/2015 - 03/2008)
2. Yamada, Shizuo: 6 articles (12/2013 - 03/2008)
3. Seto, Yoshiki: 5 articles (08/2015 - 08/2008)
4. Mitjans, Montserrat: 4 articles (12/2015 - 09/2004)
5. Igarashi, Naoko: 4 articles (08/2010 - 03/2008)
6. Dierickx, Paul J: 4 articles (10/2005 - 01/2002)
7. Kato, Masashi: 3 articles (08/2015 - 12/2013)
8. Bauer, Daniel: 3 articles (05/2014 - 08/2012)
9. Weerapreeyakul, Natthida: 3 articles (01/2014 - 01/2012)
10. Barusrux, Sahapat: 3 articles (01/2014 - 01/2012)

Related Diseases

1. Necrosis
04/01/2007 - "Genotoxicity was evaluated through the alkaline Comet assay in a concentration range defined for each toxin as below the cytotoxicity threshold IC(10), determined by the MTS and the neutral red assays, to prevent false positive results because of DNA damage stemming from necrosis. "
07/01/1915 - "2. The areas of central necrosis produced in the liver by the various substances under discussion give an acid reaction to neutral red. "
01/13/2003 - "Staurosporine (SSP)-induced apoptosis and H(2)O(2)-induced necrosis were evaluated by two cytotoxicity assays, neutral red (NR) and methyl-thiazolyl tertrazolium (MTT), in comparison with a differential dye uptake assay, using Hoechst33342/propidium iodide (Hoechst/PI). "
01/01/2003 - "The cytotoxicity of each extract in presence of human osteoblastic cell line (SaOS-2) was quantitatively assessed by measuring the viability (succinate dehydrogenase activity, MTT), the membrane integrity (the uptake of the neutral red by viable cells, NR) as well as the cell necrosis by measuring the lactate dehydrogenase (LDH) released in the culture medium. "
01/01/2013 - "The following indexes were determined in various groups of mice: body and organ weight; antibody aggregation of serum hemolysin; proliferative response of splenocytes to ConA; delayed-type hypersensitivity (DTH); natural killer cell activity; clearance of neutral red and nitric oxide (NO) release from peritoneal macrophages; apostosis and necrosis of splenocytes and thymocytes; cytokine production; and serum lysozyme. "
2. Phototoxic Dermatitis (Phototoxicity)
3. Neoplasms (Cancer)
4. Infection
5. Fever (Fevers)

Related Drugs and Biologics

1. Nile Blue
2. Nitric Oxide (Nitrogen Monoxide)
3. Platinum
4. Muramidase (Lysozyme)
5. Cisplatin (Platino)
6. 2- (3,4- dichlorophenoxy)- 5- nitrobenzonitrile
7. Smoke
8. Trypan Blue
9. Gentian Violet (Violet, Crystal)
10. Coloring Agents (Dyes)

Related Therapies and Procedures

1. Aftercare (After-Treatment)
2. Solid-State Lasers
3. Resuscitation
4. Phototherapy (Light Therapy)
5. Intravenous Infusions