|2.||Demyelinating Diseases (Demyelinating Disease)
|4.||Autoimmune Diseases (Autoimmune Disease)
|5.||Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
|1.||Zhu, Jie: 19 articles (10/2013 - 07/2002)|
|2.||Shin, Taekyun: 13 articles (12/2012 - 05/2002)|
|3.||Zhu, J: 10 articles (09/2014 - 01/2000)|
|4.||Moon, Changjong: 10 articles (12/2012 - 11/2004)|
|5.||Ahn, Meejung: 10 articles (12/2012 - 11/2004)|
|6.||Mix, Eilhard: 9 articles (08/2011 - 07/2002)|
|7.||Zhang, Zhiren: 8 articles (06/2014 - 04/2008)|
|8.||Adem, Abdu: 8 articles (05/2012 - 12/2004)|
|9.||Matsumoto, Yoh: 8 articles (06/2010 - 11/2004)|
|10.||Gold, R: 8 articles (12/2002 - 05/2000)|
05/15/2007 - "Effective treatment of experimental autoimmune neuritis with human immunoglobulin."
05/01/2007 - "Effective treatment of experimental autoimmune neuritis with Fc fragment of human immunoglobulin."
09/01/1997 - "Human immunoglobulin ameliorates rat experimental autoimmune neuritis."
01/15/2014 - "Intravenous immunoglobulin preparation attenuates neurological signs in rat experimental autoimmune neuritis with the suppression of macrophage inflammatory protein -1α expression."
12/01/2002 - "As a measure of such disruption, we measured the accumulation in the endoneurium of spinal roots and sciatic nerve of systemically administered 125I-labelled immunoglobulin in adoptive transfer experimental autoimmune neuritis (AT-EAN) in the rat. "
|2.||Myelin P2 ProteinIBA
05/15/1998 - "Treatment with P2 protein peptide 57-81 by nasal route is effective in Lewis rat experimental autoimmune neuritis."
12/01/2000 - "Lipid-free versus lipid-bound P2 protein-induced experimental allergic neuritis: clinicopathological, neurophysiological, and immunological study."
01/01/1990 - "To study the possible in vivo activity of experimental allergic neuritis (EAN) serum, we injected serum from rats immunized with whole nerve, P2 protein or adjuvant alone into the sciatic nerve of normal Lewis rats. "
08/01/1985 - "Morphologic study on experimental allergic neuritis mediated by T cell line specific for bovine P2 protein in Lewis rats."
05/01/2003 - "The P2 protein of peripheral nervous system myelin induces experimental allergic neuritis in rats, a model of Guillain-Barré syndrome in humans. "
03/01/2011 - "Differential susceptibility to experimental autoimmune neuritis in Lewis rat strains is associated with T-cell immunity to myelin antigens."
02/15/2004 - "Biphasic form of experimental autoimmune neuritis in dark Agouti rats and its oral therapy by antigen-specific tolerization."
07/01/2001 - "Here we investigated in adoptive transfer-experimental autoimmune neuritis (AT-EAN) of the Lewis rat whether induction of T cell apoptosis resulting from T cell activation by antigen therapy can be further augmented by glucocorticosteroids (GC). "
07/01/2001 - "Glucocorticosteroids modulate antigen-induced T cell apoptosis in experimental autoimmune neuritis and cause T cell proliferation in situ."
11/01/1998 - "Resistance and susceptibility to experimental autoimmune neuritis in Sprague-Dawley and Lewis rats correlate with different levels of autoreactive T and B cell responses to myelin antigens."
|4.||Interleukin-4 (Interleukin 4)IBA
01/01/2001 - "Transfer of myelin-specific cells deviated in vitro towards IL-4 production ameliorates ongoing experimental allergic neuritis."
01/01/2001 - "A causal role of IL-4 (Th2) production for recovery in experimental allergic neuritis (EAN) was indicated by experiments where Th1-like autoreactive cell populations, taken from the induction phase of the disease, were deviated to extensive secretion of IL-4 in a selective fashion, by ex vivo stimulation with autoantigen in the presence of IL-4. "
03/01/1999 - "Nasal administration of recombinant rat IL-4 ameliorates ongoing experimental autoimmune neuritis and inhibits demyelination."
10/01/2014 - "IL-10, IL-4, and STAT6 promote an M2 milieu required for termination of P0(106-125)-induced murine experimental autoimmune neuritis."
10/01/2014 - "The role of the type 2 helper T cell (Th2)-polarizing cytokines IL-4 and IL-10 has not yet been studied in P0106-125-induced murine experimental autoimmune neuritis (EAN). "
|5.||Intravenous Immunoglobulins (IVIG)FDA Link
05/15/2007 - "Experimental autoimmune neuritis (EAN) is an animal model of inflammatory demyelinating neuropathies; however, there have been conflicting reports regarding the efficacy of human IVIg in EAN. "
05/01/2007 - "IV immunoglobulin (IVIg) and its Fc fragment proved effective in preventing further progression of experimental autoimmune neuritis (EAN) in the rat induced by whole bovine peripheral nerve myelin and shortening disease duration. "
06/01/1997 - "Failure of intravenous immunoglobulin (IVIg) therapy in experimental autoimmune neuritis (EAN) of the Lewis rat."
01/15/2014 - "To clarify the mechanism of action of an intravenous immunoglobulin (IVIG) preparation in chronic inflammatory demyelinating polyneuropathy, the effects of IVIG were investigated using an experimental autoimmune neuropathy model in the rat. "
09/01/1997 - "To clarify how intravenous immunoglobulin (IVIg) acts on Guillain-Barré syndrome, we investigated the effects of intact-type IVIg treatment on experimental allergic neuritis (EAN) induced by immunizing with synthetic peptide from bovine P2 protein. "
05/28/2010 - "Upregulation of erythropoietin in rat peripheral nervous system with experimental autoimmune neuritis."
01/01/2014 - "Erythropoietin-derived nonerythropoietic peptide ameliorates experimental autoimmune neuritis by inflammation suppression and tissue protection."
08/01/2013 - "Erythropoietin is a hypoxia inducible factor-induced protective molecule in experimental autoimmune neuritis."
12/01/2012 - "Erythropoietin and autoimmune neuroinflammation: lessons from experimental autoimmune encephalomyelitis and experimental autoimmune neuritis."
01/01/2011 - "Erythropoietin ameliorates rat experimental autoimmune neuritis by inducing transforming growth factor-β in macrophages."
|7.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/01/2010 - "This study characterizes the distribution of iNOS and TNF-alpha in the spinal nerve roots, dorsal root ganglia and sciatic nerve of Lewis rats during experimental autoimmune neuritis (EAN). "
05/01/2007 - "Aggravation of experimental autoimmune neuritis in TNF-alpha receptor 1 deficient mice."
06/22/2001 - "Schwann cell apoptosis in experimental autoimmune neuritis of the Lewis rat and the functional role of tumor necrosis factor-alpha."
06/01/1993 - "In experimental autoimmune neuritis induced by active immunization (EAN) or by adoptive transfer of autoreactive T cells (AT-EAN), macrophages passing blood vessels as well as macrophages adherent to nerve fibers were TNF alpha-positive. "
02/05/2010 - "TNF-alpha receptor 1 deficiency reduces antigen-presenting capacity of Schwann cells and ameliorates experimental autoimmune neuritis in mice."
09/01/2014 - "Mitigated Tregs and augmented Th17 cells and cytokines are associated with severity of experimental autoimmune neuritis."
10/01/2013 - "Th1/Th2/Th17/Treg cytokines in Guillain-Barré syndrome and experimental autoimmune neuritis."
12/01/2002 - "The similarity of the human disease with its animal model disease experimental autoimmune neuritis (EAN), and the activation of T-cell and macrophage derived cytokines all indicate that cellular immunity is also of relevance. "
06/01/2001 - "We propose that the protective effect of cAMP-elevating agents in experimental allergic neuritis may be mediated in part via modulation of Schwann cell responses to cytokines."
04/01/2011 - "Cytokines play an important role in the pathogenesis of autoimmune diseases including Guillain-Barré syndrome (GBS) and its animal model experimental autoimmune neuritis (EAN). "
|9.||Type I Tumor Necrosis Factor ReceptorsIBA
02/01/2003 - "Exogenous soluble tumor necrosis factor receptor type I ameliorates murine experimental autoimmune neuritis."
02/01/2007 - "Soluble TNFR1 inhibits the development of experimental autoimmune neuritis by modulating blood-nerve-barrier permeability and inflammation."
05/01/2007 - "The role of tumor necrosis factor (TNF)-alpha and its receptors in the pathogenesis of experimental autoimmune neuritis (EAN) induced by P0 peptide 180-199 in TNFR1 (p55) deficient (TNFR1-/-) mice was investigated. "
02/05/2010 - "To address the role of TNF-alpha in the pathogenesis of experimental autoimmune neuritis (EAN), the current study investigated the antigen-presenting capacity of Schwann cells (SCs) in EAN induced by P0 protein peptide 106-125 in TNF-alpha receptor 1 deficient (TNFR1(-/-)) mice. "
|10.||Immunoglobulin G (IgG)IBA
06/01/2013 - "The aim of this study was to test the therapeutic efficacy of a novel recombinant polyvalent murine IgG2a Fc compound (stradomer™) in experimental autoimmune neuritis (EAN). "
07/01/1989 - "The effect of IgG immunoadsorption upon the course of chronic experimental allergic neuritis (EAN) is described. "
07/01/1989 - "IgG immunoadsorption in experimental allergic neuritis: effect on antibody levels and clinical course."
09/01/1987 - "Linear response curves from an ELISA assay: measurement of anti-myelin IgG and IgM during experimental allergic neuritis."
|1.||Transplantation (Transplant Recipients)
01/01/2007 - "To investigate the therapeutic effect of bone marrow stromal cells (BMSCs) transplantation on experimental autoimmune neuritis (EAN) and study the possible mechanism. "
10/15/2013 - "The aim of this study was to investigate the effects of transplantation of Schwann cells (SCs) co-cultured with brain-derived neurotrophic factor (BDNF) for the treatment of experimental autoimmune neuritis (EAN). "
10/15/2013 - "Transplantation of Schwann cells co-cultured with brain-derived neurotrophic factor for the treatment of experimental autoimmune neuritis."
09/01/1984 - "Attempts have been made to transfer experimental allergic neuritis (EAN) both by the intraneural and the intravenous injection of cells derived from Lewis rats with the disease into naive recipients of the same strain. "
08/01/1985 - "Light and electron microscope studies were performed on experimental allergic neuritis (EAN) passively induced in Lewis rats by the intravenous injection of T line cells specific for bovine P2 protein. "
07/01/1982 - "Similar injections of rabbit serum with experimental allergic neuritis (EAN) produced focal segmental demyelination. "
06/01/2013 - "Based on the immunopathologic similarities with experimental allergic neuritis induced after immunization with nerve proteins, disease transfer experiments with the patients' serum or with intraneural injections, and immunocytochemical studies on the patients' nerves, it appears that both cellular and humoral factors, either independently or in concert with each other, play a role in the cause of these neuropathies. "
10/01/1998 - "Experimental autoimmune neuritis (EAN) is a CD4+ T-cell-mediated demyelinating autoimmune disease, which represents an animal model for the study of the immunopathogenesis and immunotherapy of Guillain-Barré syndrome (GBS) in humans. "
08/01/1996 - "Experimental autoimmune neuritis (EAN) of Lewis rats, an inflammatory demyelinating neuropathy and model of the human Guillain-Barré syndrome (GBS), was used to evaluate the novel T cell directed immunotherapy with the anti-CD2 monoclonal antibody (mAb) OX34. "
08/01/1977 - "Experimental allergic neuritis (EAN) was induced in guinea-pigs by intradermal injection of rabbit peripheral nerve emulsified in Freund's adjuvant. "
09/01/1968 - "Experimental allergic neuritis (EAN) was produced in rats by the intradermal injection of an emulsion of peripheral nerve in Freund's adjuvant. "
08/01/1975 - "Experimental allergic neuritis (EAN) was produced in ten guinea pigs by intradermal injection of peripheral nerve antigen and complete Freund's adjuvant. "