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Experimental Autoimmune Neuritis

320  relevant articles (15 outcomes, 28 trials/studies) found for this Disease

Description: An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)

Also Known As:
Neuritis, Autoimmune, Experimental; EAN (Experimental Allergic Neuritis); EAN (Experimental Autoimmune Neuritis); Experimental Allergic Neuritis; Experimental Autoimmune Neuropathy; Neuritis, Experimental Autoimmune; Autoimmune Neuropathies, Experimental; Autoimmune Neuropathy, Experimental; Experimental Autoimmune Neuropathies; Neuropathies, Experimental Autoimmune; Neuropathy, Experimental Autoimmune; Allergic Neuritis, Experimental; Autoimmune Neuritis, Experimental; Neuritis, Experimental Allergic

Relationship Network

Disease Context: Research Results

Related Diseases

1. Syndrome
2. Demyelinating Diseases (Demyelinating Disease)
3. Inflammation
4. Multiple Sclerosis
5. Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)

Experts

1. Shin, Taekyun: 9 articles (03/2007 - 05/2002)
2. Zhu, J: 9 articles (04/2002 - 01/2000)
3. Zhu, Jie: 7 articles (05/2007 - 07/2002)
4. Zou, L P: 7 articles (03/2001 - 01/2000)
5. Moon, Changjong: 6 articles (03/2007 - 11/2004)
6. Ahn, Meejung: 6 articles (03/2007 - 11/2004)
7. Gold, R: 6 articles (12/2002 - 05/2000)
8. Toyka, K V: 6 articles (02/2002 - 05/2000)
9. Ljunggren, Hans-Gustaf: 5 articles (05/2007 - 07/2002)
10. Matsumoto, Yoh: 5 articles (03/2007 - 11/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Experimental Autoimmune Neuritis:
1. Immunoglobulins (Immunoglobulin)IBA
2. Myelin P2 ProteinIBA
3. Intravenous Immunoglobulins (IVIG)FDA Link
4. Interleukin-4 (Interleukin 4)IBA
5. AntigensIBA
6. Silicon Dioxide (Sand)IBA
7. Leukemia Inhibitory FactorIBA
12/01/2002 - "Efficacy of leukemia inhibitory factor in experimental autoimmune neuritis."
Order ALL the reference details at left...
8. ClusterinIBA
9. Reserpine (Serpasil)FDA Link
10. QuartzIBA

Therapies and Procedures

1. Immunotherapy
2. Transplantation (Transplant Recipients)
3. Homologous Transplantation (Allograft)
4. Denervation
5. Thymectomy

Best Treatments:
Research Summary Report
on Experimental Autoimmune Neuritis
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