Neoplastic Processes

11/20/2009 - "Although previous studies describe the up-regulation of purinergic P2X(3) receptors expressed at peripheral nociceptive fibers in experimental painful neoplastic processes, the analgesic efficacy of P2X(3) receptor antagonists has not been tested in these settings. "

06/01/1977 - "4-OH-A was also found to be effective in controlling estrogen-dependent reproductive and neoplastic processes. "
07/20/2021 - "Estrogens occurring in the environment can negatively affect the organisms, such as animals, through phenomena such as feminization, dysregulation of natural processes related to reproduction, lowering the physiological condition of the organisms, disturbances in the regulation of both proapoptotic and anti-apoptotic processes, and even the occurrence of neoplastic processes thus drastically decreasing animal welfare. "
01/01/2000 - "Our results are the first to suggest that PTP gamma is a potential estrogen-regulated tumor suppressor gene in human breast cancer which may play an important role in neoplastic processes of human breast epithelium."
10/01/2009 - "Ovarian hormones are not required for PRL-induced mammary tumorigenesis, but estrogen enhances neoplastic processes."

10/01/2022 - "Understanding the relationship between the coexistence of inflammatory and neoplastic processes in ovarian cancer, particularly those involving chemokines and their receptors, may help to elucidate the involvement of the studied parameters in tumor pathogenesis and could lead to improved clinical applications. "
12/01/2021 - "The Protein‑Protein Interaction (PPI) network analysis showed that tomentosin in human MM induced the downregulation of genes involved in several pathways known to lead immune‑system processes, such as cytokine‑cytokine receptor interaction, chemokine or NF‑κB signaling pathway, as well as genes involved in pathways playing a central role in cellular neoplastic processes, such as growth, proliferation, migration, invasion and apoptosis. "
08/06/2020 - "To better understand the effect of hypoxia on neoplastic processes and changes in the expression of the described proteins, we summarize the available data in a table which shows the effect of individual chemokines on angiogenesis, lymphangiogenesis, and recruitment of eosinophils, myeloid-derived suppressor cells (MDSC), regulatory T cells (Treg), and tumor-associated macrophages (TAM) to a tumor niche."

01/01/2015 - "Proton magnetic resonance spectroscopy (MRS) revealed a distinctive composition and helped rule out suppurative and neoplastic processes. "

11/01/2022 - "In this paper we discuss general aspects of the involvement of CXXC proteins and their protein partners in neoplastic processes, both from the literature data and our own studies. "
04/01/2017 - "The apparent differences in tumorigenic capabilities between the closely related zinc finger proteins ZFX and ZFY suggest that structure-function studies could represent an opportunity to gain insight into neoplastic processes in the parathyroid glands."
07/23/2023 - "The oncofetal protein OCT4 has been linked to neoplastic processes, but its role and clinical significance in RC are unknown. "
01/01/2023 - "In recent years, allosteric SHP2 inhibitors have been developed to specifically target the protein in neoplastic processes. "
08/01/2018 - "Role of the SOX18 protein in neoplastic processes."

07/01/1998 - "These data show that primary cultures of rat and mouse hepatocytes provide a model system with which to study interspecies differences in the regulation of this enzyme and to better understand the role of GGT in normal and neoplastic processes."
03/29/2011 - "Deregulation of enzymes involved in the ERα-mediated epigenetic pathway could play a vital role in ERα driven neoplastic processes. "
01/01/1989 - "The accumulation of mono- and difucosylated type 2 chain in neoplastic processes, independently of the Le and Se genes, could be due to the enzymes coded by reactivation of the H and X genes. "
06/01/2008 - "This study sought to determine if these lesions can be differentiated by the quantity or quality of expression of cyclooxygenase-2 (COX-2), an enzyme associated with both reactive and neoplastic processes. "
01/01/1999 - "The results of this study suggest that serum trace element levels and activity of related enzymes might be different in various neoplastic processes. "

01/01/2021 - "Here we present a comprehensive study of the latest discoveries which have been performed in relation to the role of miRNAs in the neoplastic processes which characterize COS, EWS and GCTB, demonstrating how these tiny molecules can act as tumour promoters or as tumour suppressors and how they can be used for improving therapeutic approaches."
01/01/2014 - "In recent years, the study of microRNAs associated with neoplastic processes has increased. "
11/01/2016 - "MicroRNAs (miRNAs) are non-encoding RNAs that play important gene-regulatory roles in neoplastic processes. "
05/15/2014 - "We developed two complementary in vitro models based on RET/PTC1 oncogene, starting from the hypothesis that miRNAs modulated by a driving PTC-oncogene are likely to have a role in thyroid neoplastic processes. "
06/01/2010 - "Dysregulation of specific miRNAs could contribute to metaplastic and neoplastic processes in the oesophageal mucosa."

06/01/2015 - "Current evidence shows that inflammatory myofibroblastic tumors are neoplastic processes resulting from chromosomal translocations that frequently cause an overexpression of ALK kinase, often assessed using immunohistochemical studies. "
04/13/2011 - "Current evidence shows that inflammatory myofibroblastic tumors are neoplastic processes resulting from chromosomal translocations that often cause an overexpression of ALK kinase, which is often assessed using immunohistochemical studies. "
12/01/2001 - "These tumors have classically been grouped together under the umbrella category of "inflammatory pseudotumor." Recent evidence shows that IMTs are in fact neoplastic processes that often harbor balanced chromosomal translocations involving the ALK kinase gene. "

03/01/2005 - "The immediate-early gene, cyclooxygenase-2 (COX-2), is induced in a variety of inflammatory and neoplastic processes and is believed to play an important role in tumorigenesis. "
06/01/2008 - "This study sought to determine if these lesions can be differentiated by the quantity or quality of expression of cyclooxygenase-2 (COX-2), an enzyme associated with both reactive and neoplastic processes. "
11/01/2011 - "Cyclooxygenase-2 (COX-2) is an enzyme involved in neoplastic processes. "
05/01/2005 - "Cyclooxygenase 2 (COX-2), an inducible prostaglandin synthase, participates in inflammatory and neoplastic processes. "

01/01/2002 - "Because differential splicing produces multiple isoforms with potentially different functions, Ikaros provides a unique model to study how post-transcriptional mechanisms may be involved in neoplastic processes. "
10/01/2021 - "HIF isoforms can play opposite roles in the development of inflammatory and neoplastic processes. "
10/01/2013 - "Leukocytes present a limited Kv repertoire, with Kv1.3 and Kv1.5 as isoforms that are involved in neoplastic processes, such as proliferation and migration. "
12/21/2012 - "PI3K isoforms are linked with inflammatory and neoplastic processes, thus they appear to be interesting subjects of a research in this respect. "

11/21/2018 - "In conclusion, cryotherapy is an effective and safe method for the treatment of esophageal neoplastic processes, ranging from early stages of low grade dysplasia to esophageal cancer."

01/01/2018 - "The second fundamental breakthrough in the field of oncology and pharmacology took place at the beginning of the '80s, thanks to molecular and cellular biology studies that allowed the development of specific drugs for some molecular targets involved in neoplastic processes, giving rise to targeted therapy. "
09/01/2014 - "It is crucially important to separate infectious processes in the kidney from other inflammatory or neoplastic processes, as this will have a major impact on therapy. "
01/01/1963 - "Indications and prospects of intralymphatic therapy in neoplastic processes of the lymph nodes of the neck]."
07/01/1999 - "Most phase III comparative studies fail to shown any overall survival improvement following multimodal therapy in comparison with surgery alone, so that there is now no scientific reason for systematic addition of radio- and/or chemotherapy to extensive surgery in potentially resectable neoplastic processes. "
02/01/2021 - "Basic science and systemic therapies literature was widely reviewed and the research and clinical trials most relevant to pediatric sarcoma and neoplastic processes found in the pediatric population were included. "

05/01/1967 - "[Studies on the use of pi-negative mesons and heavy ions in the radiation therapy of neoplastic processes]."
09/01/2022 - "Particularly in neoplastic processes, there must remain a certain degree of peri-operative flexibility with regards to the extent of the resection, and forethought to the requirement for post-operative radiotherapy; both of which further complicate choice of reconstructive option and surgical or prosthetic planning. "
06/01/1999 - "Multiple space involvement is common in inflammatory and neoplastic processes and the full extent of these lesions should be outlined to facilitate surgical or radiotherapy planning."
08/26/2016 - "Therapy-related myeloid neoplasms are neoplastic processes arising as a result of chemotherapy, radiation therapy, or a combination of these modalities given for a primary condition. "
12/01/2020 - "Several non-neoplastic processes, including infection, inflammation, demyelination, vasculitis, autoimmune disease, and post-treatment changes (radiation therapy or chemoradiation) can result in a mass-like, space-occupying lesion on conventional computed tomography (CT) or magnetic resonance (MR) imaging of the brain. "

05/01/2002 - "By localizing the lesion and identifying the underlying pathophysiology, it often predicts the underlying etiologic process; for example, (1) major T1 APR involvement with true neurogenic thoracic outlet syndrome; (2) C8 APR involvement with postmedian sternotomy brachial plexopathies; (3) supraclavicular demyelinating conduction block with classic postoperative paralysis (often confined to the upper plexus); (4) widespread infraclavicular demyelinating conduction blocks with radiation plexopathy; (5) severe progressive axon loss with neoplastic processes; (6) motor NCS abnormalities exceeding sensory NCS abnormalities for the same peripheral nervous system segment with intraspinal canal lesions (e.g., avulsions); (7) demyelinating conduction block with sparing of the pertinent sensory NCS study with multifocal motor neuropathy; and (8) lack of EDX abnormalities with hysteria, conversion reactions, and malingering, as well as with disputed neurogenic thoracic outlet syndrome. "

12/01/1994 - "Here we report the results of further investigations in animals with spontaneous neoplastic processes, including whole-body autoradiography in mice (20 minutes and 60 minutes post injection) and gamma-camera imaging studies in Wistar rats. "