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Nelson Syndrome

A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.
Networked: 27 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Pituitary Neoplasms (Pituitary Adenoma)
3. Adenoma (Adenomas)
4. Prolactinoma (Prolactinomas)
5. Cushing Syndrome

Experts

1. Scheithauer, Bernd W: 2 articles (12/2011 - 12/2010)
2. Kovacs, Kalman: 2 articles (12/2011 - 12/2010)
3. Syro, Luis V: 2 articles (12/2011 - 12/2010)
4. Sanchez, Rocío: 1 article (07/2014)
5. Arregger, Alejandro L: 1 article (07/2014)
6. Cardoso, Estela M L: 1 article (07/2014)
7. Monardes Tumilasci, Elida G: 1 article (07/2014)
8. Sandoval, Olga B: 1 article (07/2014)
9. Contreras, Liliana N: 1 article (07/2014)
10. Barber, T M: 1 article (01/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Nelson Syndrome:
1. Adrenocorticotropic Hormone (ACTH)FDA Link
2. Dopamine Agonists (Dopamine Agonist)IBA
3. Hydrocortisone (Cortisol)FDA LinkGeneric
4. Mitotane (Lysodren)FDA Link
5. Dexamethasone (Maxidex)FDA LinkGeneric
6. Growth Hormone (Somatotropin)IBA
7. HormonesIBA
8. temozolomide (Temodar)FDA LinkGeneric
9. Octreotide (Sandostatin)FDA LinkGeneric
10. Testosterone (Sustanon)FDA Link

Therapies and Procedures

1. Adrenalectomy
2. Therapeutics
3. Hypophysectomy
4. Radiotherapy