Malformed Nails (Pachyonychia)

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18 relevant articles (0 outcomes, 1 trials/studies) found for this Disease

Description: Deformities in nail structure or appearance, including hypertrophy, splitting, clubbing, furrowing, etc. Genetic diseases such as PACHYONYCHIA CONGENITA can result in malformed nails.

Also Known As:

Pachyonychia; Nail Abnormality; Nails, Malformed; Nail Abnormalities; Nails, Abnormal; Abnormal Nail; Abnormal Nails; Abnormalities, Nail; Abnormality, Nail; Malformed Nail; Nail, Abnormal; Nail, Malformed

Disease Context: Research Results

Signs and Symptoms Pathological Conditions

Anatomical Pathological Conditions

Malformed Nails: 18

Related Diseases

1.	Neoplasms (Cancer)
2.	Chloracne
3.	Ichthyosis Bullosa of Siemens
4.	Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara)
5.	Wounds and Injuries (Trauma)

Experts

1.	Smith, Frances J D: 1 article (04/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Malformed Nails:

1.	Periodic AcidIBA 04/01/2006 - "STUDY DESIGN: In a prospective study, 117 abnormal nails clinically suspect for fungal disease werefixed in a coagulant fixative, BoonFix, processed in a microwave histoprocessor to obtain optimal paraffin sections and stained with the periodic acid-Schiff (PAS) method" Order ALL the reference details at left...
2.	ParaffinIBA 04/01/2006 - "STUDY DESIGN: In a prospective study, 117 abnormal nails clinically suspect for fungal disease werefixed in a coagulant fixative, BoonFix, processed in a microwave histoprocessor to obtain optimal paraffin sections and stained with the periodic acid-Schiff (PAS) method" Order ALL the reference details at left...
3.	p-Aminosalicylic Acid (PAS)FDA Link 04/01/2006 - "STUDY DESIGN: In a prospective study, 117 abnormal nails clinically suspect for fungal disease werefixed in a coagulant fixative, BoonFix, processed in a microwave histoprocessor to obtain optimal paraffin sections and stained with the periodic acid-Schiff (PAS) method" Order ALL the reference details at left...
4.	RetinoidsIBA 04/01/2007 - "Pharmacologic agents that most frequently produce nail abnormalities include retinoids, indinavir, and cancer chemotherapeutic agents." 01/01/2003 - "Drugs that most frequently produce nail abnormalities include retinoids, indinavir, and cancer chemotherapeutic agents" 09/01/1999 - "Drugs that are well known to produce nail abnormalities include cancer chemotherapeutic agents, psoralens, retinoids, tetracyclines, antimalarials and zidovudine" Order ALL the reference details at left...
5.	Indinavir (Crixivan)FDA Link 04/01/2007 - "Pharmacologic agents that most frequently produce nail abnormalities include retinoids, indinavir, and cancer chemotherapeutic agents." 01/01/2003 - "Drugs that most frequently produce nail abnormalities include retinoids, indinavir, and cancer chemotherapeutic agents" Order ALL the reference details at left...
6.	Keratins (Keratin)IBA 05/01/2001 - "This suggests that this may be a new type of pachyonychia caused by a mutation in a so-called hard keratin." 11/15/2004 - "Keratin disorders are a novel molecular category including quite different phenotypes such as epidermolysis bullosa simplex (EBS), bullous congenital ichthyosiform erthroderma (BCIE), pachyonychia congenital (PC), steatocystoma multiplex, ichthyosis bullosa of Siemens (IBS), and white sponge nevus (WSN) of the orogenital mucosa." Order ALL the reference details at left...
7.	CosmeticsIBA 10/01/2005 - "The vast majority of patients experience brittle nails as a significant cosmetic problem and a substantial number indicate that these nail abnormalities are painful, impair daily activities, and may have a negative impact on occupational abilities" 03/01/1991 - "Nail abnormalities secondary to contact with cosmetic preparations are well documented in the literature" Order ALL the reference details at left...
8.	potassium hydroxideIBA 11/01/2008 - "Microscopic examination in potassium hydroxide and culture for fungus were performed on all clinically abnormal nails" 09/01/2000 - "Tinea unguium was defined as a positive direct examination with potassium hydroxide and culture of the etiological agent from subjects with clinically abnormal nails" Order ALL the reference details at left...
9.	Keratin-17 (Keratin 17)IBA 04/01/2004 - "Nail that mutation-keratin 17 defect in late-onset pachyonychia." Order ALL the reference details at left...
10.	Sirolimus (Rapamycin)FDA Link 06/01/2006 - "Herein, we evaluate sirolimus-induced nail abnormalities in renal transplant recipients" Order ALL the reference details at left...

Therapies and Procedures

1.	Transplantation (Transplant Recipients) 06/01/2006 - "Herein, we evaluate sirolimus-induced nail abnormalities in renal transplant recipients" Order ALL the reference details at left...
2.	Sutures (Suture) 01/01/1999 - "It is characterized by abnormal facial development, fragility of the bones with relatively mild trauma, cranial abnormalities including widely opened sutures and fontanels frontal bossing, wrinkled skin, finger and nail abnormalities" Order ALL the reference details at left...
3.	Occlusive Dressings (Occlusive Dressing) 12/01/1978 - "Thirty-five patients with a variety of nail abnormalities were successfully treated using urea preparations under occlusive dressings" Order ALL the reference details at left...
4.	Anesthesia 08/01/1992 - "Prerequisites for nail biopsy are an understanding of the surgical anatomy of the nail, adequate anesthesia and hemostasis, and a nail abnormality for which histopathology can provide the diagnosis" Order ALL the reference details at left...

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