|1.||Rydström, Jan: 2 articles (10/2011 - 07/2006)|
|2.||Ashcroft, Frances M: 2 articles (08/2011 - 07/2006)|
|3.||Cox, Roger D: 2 articles (08/2011 - 07/2006)|
|4.||Kohlhaas, Michael: 1 article (09/2015)|
|5.||Stadelmaier, Moritz: 1 article (09/2015)|
|6.||Hohl, Mathias: 1 article (09/2015)|
|7.||Duchen, Michael R: 1 article (09/2015)|
|8.||Böhm, Michael: 1 article (09/2015)|
|9.||Loewenthal, Neta: 1 article (09/2015)|
|10.||Parvari, Ruti: 1 article (09/2015)|
12/01/2009 - "Glucose intolerance in C57Bl/6 mice has been associated with mutations in the nicotinamide nucleotide transhydrogenase (Nnt) gene. "
07/01/2006 - "Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice."
04/01/2006 - "Finally, it illustrates how mouse models of glucose intolerance or diabetes can provide fresh insight into beta-cell function, using the C57BL/6J mouse, whose glucose intolerance arises from mutations in nicotinamide nucleotide transhydrogenase, as an example."
07/01/2006 - "Two recent studies have shown that the glucose intolerance and impaired insulin secretion of the C57BL/6J mouse strain results from oxidative stress due to a mutated nicotinamide nucleotide transhydrogenase. "
12/01/2014 - "This strain carries a mutation in nicotinamide nucleotide transhydrogenase (Nnt), a mitochondrial enzyme involved in NADPH production, which has been suggested to lead to glucose intolerance and beta-cell dysfunction. "
05/01/2014 - "Here, male C57BL/6JOlaHsd mice, harboring an intact nicotinamide nucleotide transhydrogenase gene, were fed a purified 40 energy% HFD for 14 weeks to induce obesity. "
01/01/2014 - "Here, we studied metabolic functions and islet gene expression profiles of C57BL/6J mice with naturally occurring nicotinamide nucleotide transhydrogenase (NNT) deletion mutation, a widely used model of diet-induced obesity and diabetes. "
10/01/2010 - "The C57BL/6J (B6/J) male mouse represents a standard for diet-induced obesity (DIO) and is unique in expressing a loss-of-function nicotinamide nucleotide transhydrogenase (Nnt) gene. "
10/01/2010 - "Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) gene."
03/01/2013 - "Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity."
04/30/1966 - "[Occurrence of pyridine nucleotide transhydrogenase in mitochondria of various ascites tumors]."
10/01/2011 - "Mammalian NADH:ubiquinone oxidoreductase (Complex I) and nicotinamide nucleotide transhydrogenase (Nnt) together regulate the mitochondrial production of H₂O₂--implications for their role in disease, especially cancer."
07/01/1965 - "II. Isocitrate dehydrogenase and transhydrogenase in tumor bearing rat liver and ascites tumor cells."
10/01/2011 - "We hypothesize that Complex I and the Δp-driven nicotinamide nucleotide transhydrogenase (Nnt) co-operate in an energy-dependent attenuation of the hydrogen-peroxide generation by Complex I. This co-operation is thought to be mediated by the NADPH/NADP⁺ ratio in the vicinity of the NADPH site of Complex I. It is proposed that the specific H₂O₂ production by Complex I, and the attenuation of it, is of importance for apoptosis, autophagy and the survival mechanism of a number of cancers. "
01/01/1971 - " The main topics of discussion are: 1) intracellular proteins binding sex hor mones and their metabolites (estrogen uptake by intact normal cells; upt ake of estrogens by mammary gland, and by mammary and other tumors; ster eospecific estrogen-binding proteids in responsive tissues; uptake of androgens by animal cells and formation of 5alpha-androstane and other derivatives; 5alpha-dihydrotestosterone-binding proteids; disposition of progesterone in various tissues); 2) testicular feminization syndrome; 3) effects of sex hormones on organ cultures, with comments on deoxyribonucleic acid synthesis and cell division in relation to tissue growth; 4) estrogen-mediated pyridine nucleotide transhydrogenase reactions; 5) intracellular "2nd messengers" and sex hormone action (polyamines); 6) physiological actions of 5beta-hydrogenated steroid metabolites and effects of sex hormones on erythropoiesis; 7) influences of sex hormones on structure, metabolism, and functions of reproductive organs (ribonucleic acid - RNA - and protein synthesis; RNA preparations and genital tissue growth; androgens and cation-activated adenosinetriphosphatase reactions; uptake of glucose and glycogen synthesis; mitochondrial reactions; gonadal hormones and sebaceous glands); and 8) medieval Chinese protoendocrinology."
|4.||Contagious Ecthyma (Orf)
10/01/2011 - "The insertion of the transposon, which occurred 16 bp upstream from the start codon of an ORF encoding a soluble pyridine nucleotide transhydrogenase (STH), negatively affected expression of the sth gene. "
03/01/1999 - "eutropha HF39 were isolated, and two insertions were mapped in an open reading frame with strong similarity to the panD gene from Escherichia coli, encoding L-aspartate-1-decarboxylase (EC 18.104.22.168), whereas two other insertions were mapped in an open reading frame (ORF) with strong similarity to the NAD(P)+ transhydrogenase (EC 22.214.171.124) alpha 1 subunit, encoded by the pntAA gene from Escherichia coli. "
|6.||Cytochromes c (Cytochrome c)
|7.||Electron Transport Complex I (NADH-CoQ Reductase)
|10.||Initiator Codon (Start Codon)