|1.||Shah, Ajay M: 15 articles (12/2015 - 10/2002)|
|2.||Gupte, Sachin A: 15 articles (12/2014 - 04/2002)|
|3.||Wolin, Michael S: 15 articles (02/2014 - 08/2005)|
|4.||Sobey, Christopher G: 12 articles (09/2014 - 02/2004)|
|5.||Popova, T N: 11 articles (12/2015 - 06/2002)|
|6.||Drummond, Grant R: 11 articles (09/2014 - 02/2004)|
|7.||Brandes, Ralf P: 10 articles (12/2015 - 03/2006)|
|8.||Park, Jeen-Woo: 10 articles (08/2014 - 03/2002)|
|9.||Schröder, Katrin: 8 articles (12/2015 - 01/2008)|
|10.||Weissmann, Norbert: 8 articles (12/2015 - 01/2005)|
12/01/2014 - "In this study, we demonstrate that the mitochondrial enzyme SHMT2 is induced upon hypoxic stress and is critical for maintaining NADPH production and redox balance to support tumor cell survival and growth."
05/01/1965 - "CHEMICAL AND HISTOCHEMICAL STUDY OF THE EFFECT OF TRANSPLANTED TUMOR UPON ACTIVITY OF ADRENAL NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DIAPHORASE IN RATS."
11/19/2015 - "Thus, R-2HG-induced hypersuccinylation contributes to the tumorigenicity of NADP(+)-IDH mutations, suggesting the potential of hypersuccinylation inhibition as an intervention for hypersuccinylation-related tumors. "
11/19/2015 - "Elucidating the tumorigenic mechanism of R-2-hydroxyglutarate (R-2HG) is critical for determining how NADP(+)-IDH mutations cause cancer. "
08/21/2015 - "Low levels of NADPH in tumors with mutated IDH1 is responsible for the enhanced fluorescence."
03/01/2002 - "The MrD of normal rats possessed more NADPH-d-positive cells, all spindle-shaped, than the other regions of the striatum, and hypoxia did not result in morphological changes of the cells but significant reduction of their quantity occurred. "
08/15/1988 - "At the same time, it can provide an emergency protection against a depletion of energy, especially in situations of anoxia where a supply of reducing equivalents through NADP-linked substrates can be maintained. "
01/15/2010 - "Therefore, the present studies were developed to determine whether NADPH could be limiting for NO production under hypoxia. "
01/01/2016 - "Developmental loss of parvalbumin-positive cells in the prefrontal cortex and psychiatric anxiety after intermittent hypoxia exposures in neonatal rats might be mediated by NADPH oxidase-2."
02/15/2014 - "This PKG-1α-activation mechanism appears to contribute to responses of isolated endothelium-removed bovine pulmonary arteries (BPA) elicited by peroxide, cytosolic NADPH oxidation resulting from G6PD inhibition, and hypoxia. "
|3.||Hypertension (High Blood Pressure)
07/01/2011 - "VPO1 is a novel regulator of vascular smooth muscle cell proliferation via NADPH oxidase-H(2)O(2)-VPO1-hypochlorous acid-ERK1/2 pathways, which may contribute to vascular remodelling in hypertension."
03/01/2008 - "The goal of this study was to test the hypothesis that increased nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity contributes to the development of hypertension-associated ED. "
10/01/2007 - "In this study we compared the reduced nicotinamide-adenine dinucleotide phosphate oxidase enzyme system of dorsal root ganglion (DRG) and sympathetic celiac ganglion (CG) and its regulation in hypertension. "
11/01/2014 - "Apocynin, a nicotinamide adenine dinucleotide phosphate inhibitor, attenuated hypertension and all oxidative stress markers in placental ischemic and normal pregnant recipient rats of placental ischemic CD4(+)Tcells (P=0.05). "
05/01/2014 - "Vascular oxidative stress is an important factor in hypertension-associated vascular damage and is mediated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation. "
09/15/2015 - "In isolated rat hearts subjected to 30 min of ischemia and reperfusion (I/R), depletion of the NADP(H) pool occurred and was most marked in the endothelium, with >85% depletion. "
02/15/2015 - "Under severe ischemia, G6PD activity and NADPH levels were reduced during reperfusion; however, blockade of TIGAR enhanced their levels and reduced oxidative stress and apoptosis. "
02/15/2015 - "After mild ischemia, but not severe ischemia, G6PD activity and NADPH levels were restored, suggesting that TIGAR activation may redirect the glycolytic pathway into gluconeogenesis or the pentose phosphate pathway to produce NADPH. "
04/01/2012 - "In the pericentral region (lamina X) containing interneurons and crossing fibers of spinal tracts, than in lamina VII and in dorsomedial part of the ventral horn (lamina VIII) we recorded a decreased number of nNOS-IR and NADPH-d positive neurons after both ischemia/reperfusion periods. "
04/01/2012 - "However, ischemia followed by longer time of survival (14 days) returned the number of nNOS-IR and NADPH-d positive neurons to control. "
10/01/2013 - "This upregulation of intracellular ROS with downregulation of NADPH levels during the early phase of ts1 infection was a separate event from the upregulation of ROS during the late phase while ts1-mediated cell death occurred. "
07/01/2012 - "Total NADP-ME activity and NADP-ME2 transcript level were enhanced after PAMP treatment and pathogen infection. "
01/01/2012 - "This case highlights that the diagnosis of mild forms of X-linked CGD caused by rare CYBB mutations and partially preserved NADPH function should be considered early in the evaluation of atypical and recurrent lung infections."
12/14/2010 - "Here, we show that a unique NADPH-dependent genetic switch regulates plant infection in response to the changing nutritional and redox conditions encountered by the pathogen. "
12/14/2010 - "An NADPH-dependent genetic switch regulates plant infection by the rice blast fungus."
|4.||Glutathione (Reduced Glutathione)
|5.||Cytochrome P-450 Enzyme System (Cytochrome P450)
|6.||Cytochromes b5 (Cytochrome b5)
|7.||NADPH Oxidase (NAD(P)H oxidase)
|9.||Nitric Oxide (Nitrogen Monoxide)
|10.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|2.||Transplantation (Transplant Recipients)