Nadolol (Corgard)

A non-selective beta-adrenergic antagonist with a long half-life, used in cardiovascular disease to treat arrhythmias, angina pectoris, and hypertension. Nadolol is also used for MIGRAINE DISORDERS and for tremor.

Also Known As:

Networked: 411 relevant articles (57 outcomes, 57 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Chen, Wen-Chi: 5 articles (11/2012 - 03/2004)
2.	Lo, Gin-Ho: 5 articles (11/2012 - 03/2004)
3.	Pope, Elena: 3 articles (01/2022 - 09/2015)
4.	Abraldes, Juan G: 3 articles (10/2020 - 06/2010)
5.	Bosch, Jaime: 3 articles (10/2020 - 01/2005)
6.	Bond, Richard A: 3 articles (10/2017 - 01/2008)
7.	Wang, Huay-Min: 3 articles (11/2012 - 10/2006)
8.	Villanueva, C: 3 articles (08/2009 - 08/2001)
9.	Hsu, Ping-I: 3 articles (08/2008 - 03/2004)
10.	Lai, Kwok-Hung: 3 articles (08/2008 - 03/2004)

Related Diseases

1.	Hemorrhage 03/01/2005 - "The aim of this study was to compare the efficacy of EVL combined with nadolol versus EVL alone as secondary prophylaxis for variceal bleeding. " 08/01/1988 - "The percentage of patients free of gastrointestinal bleeding 1 year after inclusion in the study was 83 +/- 6% (mean +/- S.D.) in the nadolol group and 80 +/- 6% in the placebo group. " 01/01/1988 - "Nadolol can prevent the first gastrointestinal bleeding in cirrhotics: a prospective, randomized study." 01/01/2018 - "Key Messages: Our findings indicated that EVL + nadolol might be the preferred choice to cirrhotic patients with one previous episode of variceal hemorrhage for preventing rebleeding. " 07/01/2010 - "Esophageal variceal bleeding occurred in 10 patients (14%) in the Combined group and nine patients (13%) in the Nadolol group (P = NS). "
2.	Hypertension (High Blood Pressure) 01/01/1980 - "Both beta-blocking agents were effective in controlling hypertension with final daily doses ranging from 80 to 320 mg. Of statistical significance, however, were the better responses of supine systolic blood pressure elicited by nadolol. " 07/01/1980 - "Nevertheless, nadolol is one of a few beta-blocking drugs which have clearly been shown to be effective in both hypertension and angina with once daily administration. " 10/01/1984 - "Nadolol is safe and effective for the long-term treatment of both hypertension and angina. " 10/01/1984 - "The efficacy of nadolol in hypertension and angina was maintained over the 2-year period. " 07/01/1989 - "Nadolol was effective and well tolerated as once-daily monotherapy for mild to moderate essential supine diastolic hypertension (SDBP) in 10 young (mean age, 39 years) and 12 elderly (mean age, 68 years) patients in a single-blind, placebo-baseline, escalating-dose study. "
3.	Migraine Disorders (Migraine) 12/01/1984 - "Nadolol and placebo comparison study in the prophylactic treatment of migraine." 04/01/1982 - "Nadolol and placebo comparison study in the prophylactic treatment of migraine." 07/15/1984 - "[Nadolol in the preventive treatment of migraine]." 01/01/1983 - "Nadolol: its use in the prophylactic treatment of migraine." 03/01/2012 - "Both flunarizine and nadolol proved to be effective in the preventive treatment of episodic migraine. "
4.	Essential Hypertension 10/01/1984 - "A study of forearm arterial and venous hemodynamics by pulsed Doppler velocimetry and plethysmography was performed in 21 patients with essential hypertension, aged 16 to 54 years, before and after short-term nadolol administration at a dose of 0.05 mg/kg. Because of a large intersubject variability in the responses of the hemodynamic parameters to nadolol, an unconventional statistic approach was used to divide the overall population of patients into two homogeneous groups. " 01/01/1982 - "An open, observer-blind, therapeutic titration trial was carried out in 28 patients with mild or moderate essential hypertension to determine the effective dose range of nadolol given once a day. " 01/01/1989 - "Clinical experience with nadolol in Nigerian patients with essential hypertension." 08/01/1985 - "We therefore studied the effects of nadolol 80 mg once daily on ambulatory blood pressure, renal and systemic haemodynamics in patients with mild to moderate essential hypertension. " 08/01/1985 - "Nadolol in essential hypertension: effect on ambulatory blood pressure, renal haemodynamics and cardiac function."
5.	Supraventricular Tachycardia 03/01/1992 - "Once a day nadolol is a safe and effective agent in the management of supraventricular tachycardia in children. " 11/01/1983 - "To assess antiarrhythmic efficacy of oral nadolol, 15 patients with recurrent supraventricular tachycardia were studied. " 08/31/1987 - "In a double-blind, placebo-controlled, parallel trial of intravenous nadolol in the treatment of sustained supraventricular tachycardia (SVT), 29 patients (20 men, 9 women) were studied. " 11/01/1983 - "Nadolol and supraventricular tachycardia: an electrophysiologic study." 03/01/2017 - "Nadolol for Treatment of Supraventricular Tachycardia in Infants and Young Children."

Related Drugs and Biologics

1.	Propranolol (Inderal)
2.	Atenolol (Tenormin)
3.	isosorbide-5-mononitrate (Ismo)
4.	Metoprolol (Toprol-XL)
5.	Timolol (Blocadren)
6.	Sotalol (Sotalol Hydrochloride)
7.	Adrenergic beta-Antagonists (beta-Adrenergic Blocking Agents)
8.	Adrenergic Receptors (Adrenergic Receptor)
9.	Verapamil (Calan)
10.	Digoxin (Digitek)

Related Therapies and Procedures

1.	Therapeutics
2.	Ligation
3.	Sclerotherapy
4.	Vagus Nerve Stimulation
5.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)