|1.||Tesfaye, Solomon: 15 articles (01/2015 - 08/2005)|
|2.||Boothman, David A: 14 articles (01/2015 - 01/2005)|
|3.||Nencioni, Alessio: 13 articles (09/2015 - 01/2009)|
|4.||Dobrowsky, Rick T: 12 articles (09/2015 - 06/2003)|
|5.||Ying, Weihai: 12 articles (04/2015 - 01/2007)|
|6.||Mayevsky, Avraham: 12 articles (01/2014 - 05/2002)|
|7.||Ross, David: 12 articles (03/2011 - 03/2002)|
|8.||Bruzzone, Santina: 11 articles (09/2015 - 10/2006)|
|9.||Vinik, Aaron I: 11 articles (02/2015 - 12/2004)|
|10.||Savchenko, A A: 11 articles (01/2014 - 09/2002)|
|1.||Peripheral Nervous System Diseases (PNS Diseases)
01/01/2015 - "Tang-tong-fang (TTF) is a Chinese herbal formula that has been shown to be beneficial in diabetic peripheral neuropathy (DPN), a common complication secondary to diabetic microvascular injury. "
10/01/2011 - "Painful diabetic peripheral neuropathy (DPN) is common, is associated with significant reduction in quality of life and poses major treatment challenges to the practising physician. "
09/01/2009 - "The purpose of this systematic review is to evaluate current evidence in the literature on the efficacy of Semmes Weinstein monofilament examination (SWME) in diagnosing diabetic peripheral neuropathy (DPN). "
11/01/2015 - "The aim of this study is to explore the relationship between serum phosphorylated neurofilament-heavy chain (pNF-H) and diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes.Serum"
09/01/2015 - "However, no previous studies have investigated its association with diabetic peripheral neuropathy (DPN). "
02/01/2012 - "Throughout a 13-week trial, DMQ was effective, with an acceptable safety profile, for treatment of DPN pain. "
01/01/2014 - "Desvenlafaxine was effective in relieving pain associated with DPN at doses of 200 and 400 mg/day, and improved activity impairment at all doses assessed. "
10/01/2013 - "WBV appears to be an effective, non-invasive treatment for pain associated with DPN. "
10/01/2013 - "The purpose of this study was to determine the efficacy of whole body vibration therapy (WBV) as a treatment for pain associated with DPN. "
04/01/2015 - "More studies are required to better evaluate the efficacy and safety of this topical compound for relieving pain in DPN."
07/07/2015 - "This improved understanding of NAD(+) metabolism revived interest in NAD(+)-boosting strategies to manage a wide spectrum of diseases, ranging from diabetes to cancer. "
02/01/2014 - "In this study we addressed the potential of NAD(+) depletion as an anti-cancer strategy and assessed the combination with radiation. "
12/01/2011 - "In summary, our study has provided the first evidence that NAD(+) treatment induces autophagy in cancer cells such as Neuro2a cells, which contributes to the NAD(+)-induced decrease in cancer cell survival."
12/16/2010 - "As tumor cells are generally hypoxic with increased NADH levels, the dynamic control of Brca1 by a 'metabolic switch' found in this study not only provides an important link between tumor metabolism and tumor suppressor expression but also suggests a potential chemo preventative or therapeutic strategy for HNSCC by blocking NADH-dependent CtBP1 activity at early stages of HNSCC carcinogenesis."
05/01/2010 - "Published clinical trials on NAD depleting drugs for cancer treatment were summarised for safety and efficacy. "
04/01/2008 - "However, the use of Ca(2+) free-media in slices from >22 month old rats improved recovery and delayed NADH hyperoxidation (2.5 min hypoxia after hsd). "
07/15/2003 - "This interaction, and consequent repression of p53-dependent transcription, is relieved under hypoxia or hypoxia-mimicking conditions that are known to increase levels of intracellular NADH. "
01/01/2002 - "IHT caused reorganization of mitochondrial energy metabolism favoring NAD-dependent oxidation and improving the protection against acute hypoxia. "
04/01/2014 - "The objective of this study was to investigate the role of exogenous NAD(+) supplementation in hypoxia/reoxygenation (HR)-stressed H9c2 cardiac myoblasts. "
07/01/1999 - "Reduced nicotinamide adenine dinucleotide videofluorescence studies have shown the heterogeneous nature of hypoxia. "
|5.||Wounds and Injuries (Trauma)
01/01/2016 - "Fittingly, in rat wounds treated with the ER‑β agonist (DPN), epidermal regeneration was accelerated. "
01/01/2014 - "AR-inhibition in vivo markedly attenuated the I/R-induced liver injuries, maintained the homeostasis of NAD(P)(H) contents and redox status, and suppressed the caspase-dependent apoptosis pathway. "
01/01/2014 - "One of the most notable protective functions of NAD is to delay axonal degenerations caused by various neurodegenerative injuries. "
05/01/2013 - "DPN-P participants also reported greater risk of hospitalizations for fall-related injuries, and greater fear of falling. "
03/01/2013 - "Therapeutic intervention with antithrombin 6 hrs after trauma restored nutritive perfusion and tissue oxygenation (functional capillary density: 469±22cm/cm; nicotinamide adenine dinucleotide autofluorescence: 61±5 aU [p < 0.05]) and reduced inflammatory leukocyte adherence (237±20 cells/mm; [p < 0.05]) toward values found in nontraumatized controls (functional capillary density: 573±13cm/cm; nicotinamide adenine dinucleotide autofluorescence: 56±2 aU; leukocyte adherence: 204±20 cells/mm;). "
|3.||Adenosine Triphosphate (ATP)
|6.||Biological Markers (Surrogate Marker)
|7.||3- (3- dimethylamino- 1- ethyl- 2- methylpropyl)phenol
|10.||Pyruvic Acid (Pyruvate)
|2.||Chinese Traditional Medicine (Traditional Chinese Medicine)
|4.||Induced Heart Arrest (Cardioplegia)