|1.||Garcia, Joe G N: 15 articles (12/2015 - 04/2006)|
|2.||Turner, Jerrold R: 9 articles (08/2013 - 04/2005)|
|3.||Wang, Ting: 7 articles (12/2015 - 01/2011)|
|4.||Wang, Yuan: 6 articles (01/2016 - 06/2013)|
|5.||Zhou, Qing: 6 articles (01/2016 - 06/2013)|
|6.||Ma, Shwu-Fan: 6 articles (10/2015 - 05/2007)|
|7.||Watterson, D Martin: 6 articles (06/2014 - 10/2005)|
|8.||Zhou, Tong: 5 articles (12/2015 - 01/2014)|
|9.||Flores, Carlos: 5 articles (10/2015 - 05/2007)|
|10.||Dudek, Steven M: 5 articles (01/2015 - 12/2008)|
02/01/2009 - "To study the role of myosin light chain kinase (MLCK) in intestinal epithelial barrier dysfunction after hypoxia. "
06/01/2015 - "In a rat model of myocardial IR and a cardiomyocyte model of hypoxia/reoxygenation (HR) injury, the cardiac or cell injury, myosin light chain kinase (MLCK) content, XO expression and activity, XO-derived products, and level of nuclear p-nmMLC20 were detected. "
01/15/2013 - "Hypoxia-reoxygenation-induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase."
02/01/2009 - "[The role of myosin light chain kinase in intestinal epithelial barrier dysfunction due to hypoxia]."
07/01/2007 - "Inhibition of the myosin light chain kinase prevents hypoxia-induced blood-brain barrier disruption."
|2.||Acute Lung Injury
11/01/2010 - "Previous studies have demonstrated an association between single nucleotide polymorphisms in the myosin light chain kinase gene and increased severity of acute lung injury in adults. "
04/01/2009 - "To investigate the influence of inhibitor of myosin light-chain kinase (MLCK) on the human pulmonary arterial endothelial cell (HPAEC) challenged with lipopolysaccharide (LPS) and LPS induced of acute lung injury (ALI) in mice. "
04/01/2009 - "[Protective effect of myosin light-chain kinase inhibitor on acute lung injury]."
06/01/2007 - "Here, we measured disease-relevant end points to test the hypothesis that inhibition of myosin light chain kinase is a potential therapeutic target for treatment of barrier dysfunction resulting from acute lung injury. "
04/01/2006 - "Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury."
|3.||Brain Injuries (Brain Injury)
06/01/2011 - "Myosin light chain kinase (MLCK) plays an important role in the reorganization of the cytoskeleton, leading to disruption of vascular barrier integrity in multiple organs, including the blood-brain barrier (BBB), after traumatic brain injury (TBI). "
07/15/2015 - "Recent studies show that myosin light chain kinase (MLCK) plays a pivotal role in development of cerebral edema, a known complication following traumatic brain injury (TBI) in children and a contributing factor to worsened neurologic recovery. "
10/01/2013 - "Inhibition of Myosin light-chain kinase attenuates cerebral edema after traumatic brain injury in postnatal mice."
02/01/2010 - "Inhibition of myosin light chain kinase reduces brain edema formation after traumatic brain injury."
09/01/2015 - "Previous studies have demonstrated that nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX)-mediated oxidative stress plays a key role in brain injury following cerebral ischemia/reperfusion (I/R) and myosin regulatory light chain kinase (MLCK) has been reported to be involved in NOX activation in lung endothelium. "
|4.||Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
03/01/1998 - "Although FH was initially developed as a compound that inhibited a myosin light chain kinase (MLCK) and had been approved for clinical use in the treatment of vasospasm after subarachnoid hemorrhage, this study shows its efficacy in blocking HIV-1 replication in latently infected patients. "
03/01/1994 - "In order to study the role of the Ca2+/calmodulin/myosin light chain kinase system in the development of chronic vasospasm caused by subarachnoid hemorrhage, the cytosolic Ca2+ level ([Ca2+]i), measured with fura-2, a fluorescent Ca2+ indicator, and contractile tension were measured simultaneously, and their quantitative correlation was examined in basilar arterial tissue obtained from the canine "two-hemorrhage" model. "
01/01/2015 - "The MYLK gene encodes the multifunctional enzyme, myosin light chain kinase (MLCK), involved in isoform-specific non-muscle and smooth muscle contraction and regulation of vascular permeability during inflammation. "
06/01/2014 - "Nonmuscle myosin light chain kinase regulates murine asthmatic inflammation."
06/01/2013 - "Claudin-2 regulates colorectal inflammation via myosin light chain kinase-dependent signaling."
02/01/2012 - "Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation."
07/05/2011 - "Nonmuscle myosin light-chain kinase (nmMLCK), the predominant MLCK isoform in endothelial cells, has been shown to contribute to vascular inflammation by altering endothelial barrier function. "
|1.||Myosin Light Chains (Myosin Essential Light Chain)
|4.||Calmodulin (Calcium-Dependent Activator Protein)
|5.||Proteins (Proteins, Gene)
|6.||Protein Kinases (Protein Kinase)
|9.||Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
|2.||Artificial Respiration (Mechanical Ventilation)
|3.||Positive-Pressure Respiration (PEEP)