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Myosin-Light-Chain Kinase

An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.
Also Known As:
Myosin LCK; Myosin Regulatory Light-Chain Kinase; Kinase, Myosin; Kinase, Myosin-Light-Chain; LCK, Myosin; Myosin Light Chain Kinase; Myosin Regulatory Light Chain Kinase; Myosin Kinase; ATP:myosin-light-chain O-phosphotransferase
Networked: 182 relevant articles (0 outcomes, 23 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Garcia, Joe G N: 15 articles (12/2015 - 04/2006)
2. Turner, Jerrold R: 9 articles (08/2013 - 04/2005)
3. Wang, Ting: 7 articles (12/2015 - 01/2011)
4. Wang, Yuan: 6 articles (01/2016 - 06/2013)
5. Zhou, Qing: 6 articles (01/2016 - 06/2013)
6. Ma, Shwu-Fan: 6 articles (10/2015 - 05/2007)
7. Watterson, D Martin: 6 articles (06/2014 - 10/2005)
8. Zhou, Tong: 5 articles (12/2015 - 01/2014)
9. Flores, Carlos: 5 articles (10/2015 - 05/2007)
10. Dudek, Steven M: 5 articles (01/2015 - 12/2008)

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5. Inflammation

Related Drugs and Biologics

1. Myosin Light Chains (Myosin Essential Light Chain)
2. Myosin-Light-Chain Phosphatase
3. Contractile Proteins
4. Calmodulin (Calcium-Dependent Activator Protein)
5. Proteins (Proteins, Gene)
6. Protein Kinases (Protein Kinase)
7. occludin
8. ML 9
9. Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
10. Melatonin

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1. Critical Care
2. Artificial Respiration (Mechanical Ventilation)
3. Positive-Pressure Respiration (PEEP)
4. Ligation
5. Lenses