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Myosarcoma

A general term for a malignant neoplasm derived from muscular tissue. (Stedman, 25th ed)

Also Known As:

Myosarcomas

Networked: 33 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Neoplasms: 1324753
- Neoplasms by Histologic Type: 2
  - Connective and Soft Tissue Neoplasms: 1
    - Sarcoma: 23140
      - Myosarcoma: 33
        Rhabdomyosarcoma: 3956
    - Muscle Tissue Neoplasms: 89
      - Myosarcoma: 33
        Rhabdomyosarcoma: 3956

Related Diseases

1.	Carcinoma (Carcinomatosis)
2.	Neoplasms (Cancer)
3.	Sarcoma (Soft Tissue Sarcoma)
4.	Fibrosarcoma
5.	Squamous Cell Carcinoma (Epidermoid Carcinoma)

Experts

1.	Bernard, Angela: 1 article (04/2015)
2.	Cabiddu, Maria G: 1 article (04/2015)
3.	Lacroix, Céline: 1 article (04/2015)
4.	Leyssen, Pieter: 1 article (04/2015)
5.	Neyts, Johan: 1 article (04/2015)
6.	Pompei, Raffaello: 1 article (04/2015)
7.	Chen, H Y: 1 article (02/2009)
8.	Kathirvel, P: 1 article (02/2009)
9.	Lai, P S: 1 article (02/2009)
10.	Yee, W C: 1 article (02/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Myosarcoma:

1.	Sepharose (Agarose)IBA 02/01/2009 - "On agarose gel electrophoresis analysis, six of eight ATMs showed trans-splicing efficacy when applied to DMPK mini-gene construct transcripts, of which three were able to trans-splice endogenous DMPK pre-mRNA transcripts in myosarcoma cells, with trans-splicing efficiency ranging from 1.81 to 7.41%. "
2.	RNA Precursors (Precursor, mRNA)IBA 02/01/2009 - "ATMs designed to target intron 14 of DMPK pre-mRNA transcripts were tested for their ability to trans-splice the transcripts of a DMPK mini-gene construct and the endogenous DMPK transcripts of human myosarcoma cells (CCL-136). " 02/01/2009 - "On agarose gel electrophoresis analysis, six of eight ATMs showed trans-splicing efficacy when applied to DMPK mini-gene construct transcripts, of which three were able to trans-splice endogenous DMPK pre-mRNA transcripts in myosarcoma cells, with trans-splicing efficiency ranging from 1.81 to 7.41%. "
3.	Cadmium Chloride (Cadmium Dichloride)IBA 02/01/2004 - "To study, the cytotoxic effects of some biological and chemical agents on G1, S, G2, M and G0 phases of liver and colon carcinomas and myosarcoma cells obtained with chemical carcinogens dimethylbenzanthracene (DMBA) and cadmium chloride. "
4.	CarcinogensIBA 02/01/2004 - "To study, the cytotoxic effects of some biological and chemical agents on G1, S, G2, M and G0 phases of liver and colon carcinomas and myosarcoma cells obtained with chemical carcinogens dimethylbenzanthracene (DMBA) and cadmium chloride. "
5.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/01/1988 - "Treatment of sensitive human myosarcoma cells (KYM-S) with exogenous tumor necrosis factor (r-TNF) resulted in the production of TNF by the cells. " 07/25/1988 - "The cell dynamics of the receptor for tumor necrosis factor (TNF) were examined in TNF-sensitive KYM cells derived from human myosarcoma. " 02/01/1988 - "The cell dynamics of the receptor on tumor necrosis factor (TNF) were studied with the use of TNF-sensitive KYM cells derived from human myosarcoma. " 06/01/1988 - "The existence of a tumor necrosis factor (TNF) receptor on KYM human myosarcoma cells was elucidated by Scatchard plot and cross-linking analysis. "
6.	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 07/25/1988 - "Continuous internalization of tumor necrosis factor receptors in a human myosarcoma cell line." 02/01/1988 - "[Continuous internalization of TNF receptors in a human myosarcoma cell line]." 06/01/1988 - "The existence of a tumor necrosis factor (TNF) receptor on KYM human myosarcoma cells was elucidated by Scatchard plot and cross-linking analysis. "
7.	Cytostatic AgentsIBA 01/01/1978 - "[Antitumor activity of cytostatics on a newly transplanted tumor in mice, myosarcoma ISM]." 02/10/1967 - "[Monocytic leukemia with gamma-G-paraproteinemia after roentgen irradiation and cytostatic therapy of a myosarcoma]."
8.	MyogeninIBA 10/01/1998 - "Prompted by a DGCT in which a subpopulation of cells was desmin positive and in which an erroneous diagnosis of myosarcoma was made, we analyzed the frequency of desmin, myogenin, MyoD1, and muscle-specific actin immunoreactivity in 45 well-characterized GCTs. " 08/01/2001 - "High-molecular-weight caldesmon and myogenin are useful for differentiating urogenital PMTs from myosarcomas."
9.	Hydroxyl RadicalIBA 04/01/1989 - "A similar increase in hydroxyl radical production in the presence of rhTNF was also detected with TNF-sensitive human myosarcoma-derived KYM cells, but no such increase was detected with TNF insensitive human embryonic lung fibroblast HEL cells. " 10/01/1988 - "The increase of hydroxyl radical production stimulated by rhTNF was also detected in TNF sensitive human myosarcoma derived KYM cells as well as in L-M cells, but no change was detected in TNF insensitive human embryonic lung fibroblast HEL cells. "
10.	Monoclonal AntibodiesIBA 03/01/1983 - "Hematoporphyrin was chemically coupled to monoclonal antibodies directed to the DBA/2J myosarcoma M-1. " 01/01/1988 - "carcinoma, lymphoma, myosarcoma, etc. Furthermore, monoclonal antibodies to individual cytokeratin proteins can be used to distinguish between several types of epithelial tissues and different types of carcinomas. "

Therapies and Procedures

1.	Therapeutics 01/01/1982 - "It is concluded that the management of gastric myosarcomas can be planned according to these prognostic factors and that multimodal therapy of tumors with adverse factors warrants consideration." 02/10/1967 - "[Monocytic leukemia with gamma-G-paraproteinemia after roentgen irradiation and cytostatic therapy of a myosarcoma]."
2.	Photochemotherapy (Photodynamic Therapy) 03/01/2001 - "Complex treatment with acetylsalicylic acid, heparin, and dexamethasone improves the efficiency of photodynamic therapy in rats with myosarcoma-I."
3.	Pelvic Exenteration 05/01/1956 - "Pelvic exenteration for polypoid myosarcoma (sarcoma botryoides) of the urinary bladder of an infant."
4.	Nephrectomy 04/01/1950 - "[Myosarcoma of the kidney, benign tumor of the kidney and partial nephrectomy]."
5.	Drug Therapy (Chemotherapy) 05/01/1968 - "Chemotherapy of myosarcoma (leio- and rhabdomyosarcoma)."