Myoglobinuria

01/03/2022 - "Biochemical investigations on admission revealed hyperCKemia (590 000 U/L), transaminitis (AST, 628; ALT, 160), and normal creatinine (0.83), without myoglobinuria. "
11/03/2014 - "The diagnosis is confirmed by myoglobinuria, and an elevated serum Creatinine Phosphokinase (CPK) level, usually 10 times the normal range. "
11/01/1995 - "Characteristic laboratory features include elevated serum creatinine phosphokinase (CPK) (in excess of 90,000 IU/L) and myoglobinuria. "
02/01/2017 - "Just 3 h later, she complained of severe limb muscle pain, with serum creatinine phosphokinase elevated to 32 019 U/L and myoglobinuria. "
12/01/2004 - "The sequential addition of admission laboratory values for serum creatinine > or =1.5 mg/dL (positive predictive value [PPV] = 33%), base deficit < or = -4 (PPV = 52%), serum CK level > or =5,000 U/L (PPV = 80%), and myoglobinuria increases the ability to predict which patients will develop dialysis-requiring acute renal failure after an episode of rhabdomyolysis. "

10/01/1990 - "Certain clinical features were found to be of more value as predictors than others; these included a high creative kinase and myoglobinuria. "
05/01/2015 - "Compared with DMD, BMD is clinically more heterogeneous, with initial presentation in the teenage years and loss of ambulation beyond the age of 16 and a wide spectrum of clinical presentations, ranging from only myalgias and muscle cramps to exercise intolerance and myoglobinuria, asymptomatic elevation of serum creatin-kinase, or mild limb-girdle weakness and quadriceps myopathy. "
10/01/2022 - "The haematological investigations revealed a markedly raised Creatinine Kinase (74,400 U/L) and myoglobinuria. "
01/01/2020 - "It is characterized by marked elevations of creatinine kinase levels and myoglobinuria. "
03/01/1999 - "Laboratory tests revealed marked elevation of creatinine kinase(CK) levels and myoglobinuria. "

07/01/1993 - "From a history of use of succinylcholine as a muscle relaxant during operation, myoglobinuria appears to be secondary to muscle damage caused by succinylcholine."
07/01/1993 - "Myoglobinuria following the use of succinylcholine."
11/01/1968 - "Myoglobinuria following the use of suxamethonium chloride. "
05/01/1968 - "Myoglobinuria following anaesthesia including suxamethonium."
11/01/1964 - "MYOGLOBINURIA WITH ACUTE RENAL FAILURE POSSIBLY INDUCED BY SUXAMETHONIUM. "

09/27/2021 - "The intense exercise also causes a marked decrease of glycogen in type I and II muscle fibres that can produce myoglobinuria and muscular necrosis. "
08/01/2001 - "There are 11 hereditary disorders of glycogen metabolism affecting muscle alone or together with other tissues, and they cause two main clinical syndromes: episodic, recurrent exercise intolerance with cramps, myalgia, and myoglobinuria; or fixed, often progressive weakness. "
12/01/1999 - "The syndrome of exercise intolerance, cramps, and myoglobinuria is a common presentation of metabolic myopathies and has been associated with several specific inborn errors of glycogen or lipid metabolism. "
09/01/2005 - "McArdle's disease of isolated deficiency in glycogen degradation in skeletal muscles has the potential of creating perioperative anaesthesiological problems; such as hypoglycaemia, rhabdomyolysis, myoglobinuria, acute renal failure and possibly malignant hyperthermia. "
02/01/2000 - "Patients with disorders of glycogen, lipid, or mitochondrial metabolism in muscle may present with dynamic findings (i.e., exercise intolerance, reversible weakness, and myoglobinuria) or progressive muscle weakness, or both. "

04/01/1989 - "The elevated CK levels initially decreased, serum potassium levels were found to be within normal limits, and myoglobinuria was not detected during the further course. "
10/22/1966 - "[Potassium depletion and myoglobinuria caused by the use of licorice]."
01/31/1987 - "Symptoms linked with serum Potassium depletion: asthenia, paralysis (due to Potassium deficiency), myopathy with myoglobinuria. "
01/01/1989 - "The poor clinical features contrasted with the severe biological disturbances: 1 mmol.l-1 serum potassium, pH 7.26, 19 mmHg PaCO2, 8 mmol.l-1 bicarbonate, myoglobinaemia and myoglobinuria. "
07/01/1976 - "Electrocardiographic changes, venous and arterial plasma potassium and calcium levels, CPK changes (12 patients) and appearance of myoglobinuria (35 patients) were followed. "

08/14/1992 - "The cause of the symptoms was rhabdomyolysis with an increased creatinine activity of 1000 U/l and marked myoglobinuria (1600 micrograms/l), as well as renal failure with normal uric acid and a creatinine clearance of 3 ml/min per 1.73 m2. "
08/01/2008 - "Laboratory examinations showed acute renal failure due to myoglobinuria and revealed alanine transaminase 428 U/l, aspartate transaminase 1,400 U/l, blood urea nitrogen 119 mg/dl, creatinin 3.6 mg/dl, uric acid 13 mg/dl, and serum creatinine kinase (CK) 33,766 U/l. "

10/01/1994 - "We recommend performing a medical history, physical examination, SMA-7, calcium, CPK if there is possible myoglobinuria, alcohol and drug screens, computed tomography scan, and lumbar puncture as part of the medical clearance of these patients."
07/01/1976 - "Electrocardiographic changes, venous and arterial plasma potassium and calcium levels, CPK changes (12 patients) and appearance of myoglobinuria (35 patients) were followed. "

07/01/1976 - "Pretreatment with a small dose of d-tubocurarine is effective in preventing or decreasing fasciculations, plasma potassium and CPK changes and myoglobinuria described after the intravenous administration of succinylcholine. "

12/20/2012 - "Despite rapid clearance of the parasitemia with intravenous artesunate and aggressive hydration maintaining good urine output, his myoglobinuria and acidosis worsened, progressing to uremia requiring renal replacement therapy. "

08/01/2014 - "Laboratory studies were notable for myoglobinuria and markedly elevated plasma creatine kinase (CK) level of 7315 U/L. "
01/01/2012 - "To address this, a six-minute ambulation assay, serum creatine kinase, and myoglobinuria were investigated for the mdx mouse, a dystrophinopathy mouse model commonly used in pre-clinical studies. "
09/01/2023 - "The diagnosis is based on the increase in serum creatine kinase, which is sometimes associated with myoglobinuria. "
04/23/2023 - "Further investigation revealed myoglobinuria and significantly elevated levels of creatine phosphokinase. "
05/01/2021 - "Laboratory testing for myoglobinuria is pathognomonic but so often not present during the time of testing that serum creatine kinase should always be sent when the diagnosis is suspected. "

10/01/1993 - "Myoglobinuria was documented in all five patients and cleared within 24 hours of physiologic amputation in four patients. "
10/01/1993 - "Physiologic amputation prevents myoglobinuria from lower extremity myonecrosis."
07/01/2005 - "Patients with gross myoglobinuria are at higher risk of requiring fasciotomy and/or amputation."
07/01/2005 - "Amputation was predicted by a logistic model incorporating myoglobinuria, undergoing a previous fasciotomy, and age, with an overall accuracy of 73.3%. "
10/01/1993 - "Physiologic amputation may be appropriately used in patients with myoglobinuria due to extremity myonecrosis who are deemed too critically ill to survive emergency amputation."

07/01/2005 - "Fasciotomy was predicted by presence of myoglobinuria with an overall accuracy of 72.8%. "
12/24/2016 - "The patient was diagnosed with TCS and underwent emergent decompression fasciotomy and aggressive IV fluids for protection against myoglobinuria. "
07/01/2005 - "Patients with gross myoglobinuria are at higher risk of requiring fasciotomy and/or amputation."
07/01/2005 - "Amputation was predicted by a logistic model incorporating myoglobinuria, undergoing a previous fasciotomy, and age, with an overall accuracy of 73.3%. "
01/01/2017 - "Decompressive fasciotomy was performed followed by an intensive care unit (ICU) stay for associated myoglobinuria secondary to rhabdomyolysis. "

12/01/2008 - "Urgent fasciotomies were performed and the patient underwent urgent renal replacement therapy with continuous hemodialysis for acute renal failure due to myoglobinuria. "
01/01/2022 - "Clinical course was heralded by rhabdomyolysis and myoglobinuria resulting in multi-organ failure including respiratory failure necessitating mechanical ventilation, hemodynamic compromise with need for inotropic support, and an acute renal failure requiring renal replacement therapy. "
12/20/2012 - "Despite rapid clearance of the parasitemia with intravenous artesunate and aggressive hydration maintaining good urine output, his myoglobinuria and acidosis worsened, progressing to uremia requiring renal replacement therapy. "

07/01/1976 - "Pretreatment with a small dose of d-tubocurarine is effective in preventing or decreasing fasciculations, plasma potassium and CPK changes and myoglobinuria described after the intravenous administration of succinylcholine. "

12/24/2016 - "The patient was diagnosed with TCS and underwent emergent decompression fasciotomy and aggressive IV fluids for protection against myoglobinuria. "