Mutism (Selective Mutism)

Subscribe to Selected New Research on Mutism

73 relevant articles (9 outcomes, 7 trials/studies) found for this Disease

Description: The inability to generate oral-verbal expression, despite normal comprehension of speech. This may be associated with BRAIN DISEASES or MENTAL DISORDERS. Organic mutism may be associated with damage to the FRONTAL LOBE; BRAIN STEM; THALAMUS; and CEREBELLUM. Selective mutism is a psychological condition that usually affects children characterized by continuous refusal to speak in social situations by a child who is able and willing to speak to selected persons. Kussmal aphasia refers to mutism in psychosis. (From Fortschr Neurol Psychiatr 1994; 62(9):337-44)

Also Known As:

Selective Mutism; Elective Mutism; Kussmaul's Aphasia; Mutism, Conversion; Mutism, Elective; Mutism, Organic; Mutism, Selective; Mutism, Voluntary; Aphasia, Kussmaul; Aphasia, Kussmaul's; Conversion Mutism; Conversion Mutisms; Elective Mutisms; Kussmauls Aphasia; Mutisms; Mutisms, Conversion; Mutisms, Elective; Mutisms, Organic; Mutisms, Voluntary; Organic Mutism; Organic Mutisms; Voluntary Mutism; Voluntary Mutisms; Kussmaul Aphasia

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3414

Neurologic Manifestations: 2878

Neurobehavioral Manifestations: 297

Communication Disorders: 84

Language Disorders: 73

Speech Disorders: 89

Mutism: 73

Signs and Symptoms Pathological Conditions

Signs and Symptoms

Neurologic Manifestations: 2878

Neurobehavioral Manifestations: 297

Communication Disorders: 84

Language Disorders: 73

Speech Disorders: 89

Mutism: 73

Mental Disorders: 1709

Mental Disorders Diagnosed in Childhood

Mutism: 73

Related Diseases

1.	Mutism (Selective Mutism)
2.	Craniocerebral Trauma (Head Injury)
3.	Seizures (Seizure)
4.	Postoperative Pain
5.	Tremor (Tremors)

Experts

1.	Kaakeh, Yaman: 1 article (02/2008)
2.	Stumpf, Janice L: 1 article (02/2008)
3.	Denysenko, Lex: 1 article (05/2007)
4.	O'Donnell, Margot M: 1 article (05/2007)
5.	Williams, John P: 1 article (05/2007)
6.	Weinrieb, Robert: 1 article (05/2007)
7.	Gopalakrishnan, R: 1 article (01/2007)
8.	Basanth, K K: 1 article (01/2007)
9.	Jacob, K S: 1 article (01/2007)
10.	Bush, Eric: 1 article (12/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mutism:

1.	Fluoxetine (Prozac)FDA LinkGeneric 09/01/1994 - "Subjects treated with fluoxetine were significantly more improved than placebo-treated subjects on parent's ratings of mutism change and global change" 09/01/1994 - "OBJECTIVE: To evaluate the efficacy of treatment with fluoxetine in reducing symptoms associated with elective mutism" 05/01/1996 - "Fluoxetine treatment of children with selective mutism: an open trial." 09/01/1994 - "Treatment of elective mutism with fluoxetine: a double-blind, placebo-controlled study." 06/01/1995 - "Fluoxetine for (s)elective mutism." Order ALL the reference details at left...
2.	Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 02/01/2008 - "Although data are limited to case reports and trials with small patient populations and short follow-up periods, some patients with selective mutism respond to therapy with selective serotonin reuptake inhibitors (SSRIs)" 02/01/2008 - "Treatment of selective mutism: focus on selective serotonin reuptake inhibitors." 01/01/1999 - "Additional investigation of the use of selective serotonin reuptake inhibitors in treating selective mutism is warranted." 01/01/2002 - "Selective serotonin reuptake inhibitors and selective monoamine oxidase inhibitors have also been reported to be helpful when treating children with selective mutism" 01/01/1999 - "The authors conclude that phenelzine can be an effective treatment for selective mutism, but because of the possibility of serious food and drug interactions and the necessary dietary restrictions, it should be reserved for cases that do not respond to behavior therapy and fluoxetine or other specific serotonin reuptake inhibitors." Order ALL the reference details at left...
3.	Amobarbital (Amsal)IBA 02/01/1992 - "CONCLUSIONS: Intravenous amobarbital is superior to saline in relieving catatonic mutism, although only 50% of these patients responded" 11/01/1992 - "Although the amobarbital interview is an effective means of temporarily relieving catatonic mutism, some catatonic patients simply fall asleep during an amobarbital interview" 11/01/1992 - "A clinical case of mutism is described in this research to illustrate the usefulness of the amytal interview" 02/01/1992 - "The authors postulated that a randomized blind comparison of intravenous amobarbital and saline would demonstrate the superiority of amobarbital in relieving catatonic mutism" 02/01/1992 - "Controlled investigation of the amobarbital interview for catatonic mutism." Order ALL the reference details at left...
4.	Phenelzine (Nardil)FDA Link 01/01/1999 - "Four children, ages 5 1/2 to 7 years, diagnosed with selective mutism and successfully treated with phenelzine are presented" 01/01/1999 - "Phenelzine treatment of selective mutism in four prepubertal children." 09/01/1990 - "A 7-year-old girl with a 2-year history of elective mutism was successfully treated with phenelzine" 09/01/1990 - "Phenelzine treatment of elective mutism: a case report." 01/01/1999 - "The authors conclude that phenelzine can be an effective treatment for selective mutism, but because of the possibility of serious food and drug interactions and the necessary dietary restrictions, it should be reserved for cases that do not respond to behavior therapy and fluoxetine or other specific serotonin reuptake inhibitors." Order ALL the reference details at left...
5.	Methylphenidate (Ritalin)FDA LinkGeneric 08/01/1985 - "A case of akinesia and mutism is described in a menopausal, depressed woman with onset following a mood challenge with 40 mg of methylphenidate taken orally over a 3-hour period" 08/01/1985 - "Akinesia and mutism following a methylphenidate challenge test." 04/01/1989 - "Methylphenidate eliminated mutism in a catatonic schizophrenic after Amytal had failed" 04/01/1989 - "This suggests that methylphenidate has a useful role in the clinical evaluation of the mute patient who fails to respond to Amytal and that 2 psychopharmacological varieties of catatonic mutism may exist." 04/01/1989 - "Methylphenidate in amytal-resistant mutism." Order ALL the reference details at left...
6.	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA 01/01/2002 - "Selective serotonin reuptake inhibitors and selective monoamine oxidase inhibitors have also been reported to be helpful when treating children with selective mutism" Order ALL the reference details at left...
7.	Diazepam (Valium)FDA LinkGeneric 09/01/1996 - "Traumatic mutism in severe head injury relieved by oral diazepam." Order ALL the reference details at left...
8.	zonisamide (Zonegran)FDA LinkGeneric 10/01/2002 - "Zonisamide was administered at age 6 years, which was effective against her seizures, but selective mutism, violent behaviour, and lack of concentration developed at age 10 years" 10/01/2002 - "Selective mutism and obsessive compulsive disorders associated with zonisamide." Order ALL the reference details at left...
9.	BenzodiazepinesIBA 11/01/1988 - "Benzodiazepines for catatonic symptoms, stupor, and mutism." 08/01/1999 - "The purpose of this study was to compare the effects of LO and oxazepam (OX), benzodiazepines with comparable pharmacokinetics, on psychomotor retardation and mutism associated with psychiatric disorder" 08/01/1999 - "BACKGROUND: An increasing number of case reports indicate a superior therapeutic response of catatonialike symptoms, such as severe psychomotor disturbance and mutism, associated with psychiatric disorder to the benzodiazepine lorazepam (LO)" 04/01/1987 - "In a single patient suffering from a major depressive episode with melancholia (DSM-III), both severe psychomotor symptoms, such as stupor and mutism, and mood disturbances could be abolished completely and promptly by administration of the benzodiazepine lorazepam" Order ALL the reference details at left...
10.	Sertraline (Zoloft)FDA LinkGeneric 01/01/1999 - "In this single-case research study, we examined the efficacy and acceptability of sertraline treatment in children diagnosed with selective mutism" 01/01/1999 - "Sertraline treatment of 5 children diagnosed with selective mutism: a single-case research trial." 01/01/1999 - "Two of the five participants no longer met diagnostic criteria for selective mutism following less than 10 weeks of 100 mg sertraline treatment" Order ALL the reference details at left...

Therapies and Procedures

1.	Patient-Controlled Analgesia (Analgesia, Patient Controlled) 01/01/1997 - "Postoperative pain relief for a patient with elective mutism by patient controlled analgesia]" Order ALL the reference details at left...
2.	Transplants (Transplant) 05/01/2007 - "Catatonic mutism after liver transplant rapidly reversed with lorazepam." 02/01/2003 - "Tacrolimus (FK506), an immunosuppressant, has been associated with mutism in adults after liver transplant" 02/01/2003 - "Tacrolimus (FK506)-induced mutism after liver transplant." 01/01/1996 - "Cyclosporine-associated mutism in liver transplant patients." 03/23/2004 - "Transient mutism was observed in a liver transplant patient under immunosuppressant therapy with cyclosporine A and antifungal prophylaxis with amphotericin B" Order ALL the reference details at left...
3.	Liver Transplantation 01/11/2005 - "Reversible diffusion MRI abnormalities and transient mutism after liver transplantation." 03/23/2004 - "Reversible diffusion MRI abnormalities and transient mutism after liver transplantation." 09/27/2000 - "Tacrolimus-associated mutism after orthotopic liver transplantation." 09/27/2000 - "BACKGROUND: Mutism/speech apraxia has been well documented as a toxic effect of cyclosporine after liver transplantation but has been reported only rarely with tacrolimus" Order ALL the reference details at left...
4.	Intravenous Anesthesia 01/01/2003 - "An unusual complication of total intravenous anesthesia: mutism." 12/01/2003 - "Mutism as a complication of total intravenous anesthesia by propofol." 07/01/2003 - "Mutism as a complication of total intravenous anesthesia by propofol." Order ALL the reference details at left...
5.	Combined Modality Therapy 08/01/1996 - "Successful multimodal treatment of a child with selective mutism: a case report." 07/01/1995 - "Case study: fluoxetine in the multimodal treatment of a preschool child with selective mutism." Order ALL the reference details at left...

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>