|1.||Konieczny, J: 7 articles (01/2009 - 01/2000)|
|2.||Wolfarth, S: 7 articles (02/2007 - 01/2000)|
|3.||Pilc, A: 6 articles (02/2007 - 01/2000)|
|4.||Wardas, J: 5 articles (02/2007 - 06/2001)|
|5.||Ossowska, K: 5 articles (02/2007 - 01/2000)|
|6.||Lorenc-Koci, E: 5 articles (12/2003 - 01/2000)|
|7.||Rosenberg, Henry: 3 articles (01/2015 - 06/2005)|
|8.||Pollock, Neil: 2 articles (01/2015 - 01/2007)|
|9.||Stowell, Kathryn: 2 articles (01/2015 - 01/2007)|
|10.||Nisijima, Koichi: 2 articles (01/2013 - 01/2012)|
|1.||Dopamine (Intropin)FDA LinkGeneric
10/01/2001 - "Muscle rigidity associated with antipsychotic drug treatment is believed to result from reduced striatal dopamine neurotransmission. "
10/01/1996 - "However, in spite of relatively large lesions of nigral dopamine cells, already four weeks after the lesion, muscle rigidity and the respective electromyographic activity diminished dramatically, which seems to result from very effective compensatory mechanisms operating in young lesioned rats. "
01/01/1988 - "This lack of muscle rigidity, however, appears to be consistent with NMS-like syndromes accompanying other conditions involving dopamine depletion rather than blockade. "
10/14/1985 - "Muscular rigidity and delineation of a dopamine-specific neostriatal subregion: tonic EMG activity in rats."
04/01/1983 - "Whether the delayed behavioural activation and the increase in dopamine (DA) turnover in the striatum reflect signs of rebound effects or of counter-regulatory processes directed against locomotor depression and/or muscular rigidity was studied in rats. "
|2.||Fentanyl (Sublimaze)FDA LinkGeneric
06/01/1989 - "This study was undertaken to search for an alternative experimental model in the evaluation of fentanyl-induced muscle rigidity. "
07/01/2012 - "The cause of difficult ventilation was surmised to be upper airway reflex or muscle rigidity caused by reaction to fentanyl. "
08/01/2002 - "During fentanyl-induced muscular rigidity BIS recordings reflect EMG variations. "
08/01/2002 - "Our aims were: to evaluate variations of BIS in the presence of high EMG activity associated with muscular rigidity after administration of high-dose fentanyl; to compare muscular rigidity, as measured by the EMG variable of the BIS monitor, in patients who were administered two different dosages of fentanyl at induction of cardiac anaesthesia. "
03/01/2000 - "To assess the occurrence of muscle rigidity after fentanyl administration in premature and term neonates. "
|3.||Halothane (Fluothane)FDA Link
08/01/2004 - "At 4 wk of age, broilers from 4 commercial strains (n = 1,000) were subjected to 3% halothane gas and classified as either halothane positive (HAL+) or negative (HAL-) based on muscle rigidity within the legs. "
05/01/2000 - "Birds were classified as halothane sensitive (HAL+) or halothane nonresponder (HAL-), in which HAL+ birds showed signs of muscle rigidity in the legs upon removal from halothane gas, and HAL- birds showed no stiffness response. "
11/01/1999 - "In Experiment 1, a commercial strain of 4-wk-old male turkeys (n = 116) was exposed to 3% halothane gas for 3 min (6 L/min) and examined for leg muscle rigidity. "
03/01/1987 - "Thus, the presence of a halothane-sensitive abnormality in the skeletal muscles, in and of itself, is not always sufficient for development of in vivo muscle rigidity during a brief halothane test. "
03/01/1987 - "A few (6%) pigs that should have been MH susceptible on the basis of parental genotype did not develop muscle rigidity in response to repeated halothane tests. "
|4.||Dantrolene (Dantrium)FDA LinkGeneric
11/01/1999 - "After hydration and dantrolene sodium were administered, muscular rigidity gradually improved and serum levels of CK became normal. "
04/01/2003 - "We should administer dantrolene, recognizing the fact that the use of dantrolene is one of the symptomatic treatments for muscle rigidity."
06/01/2002 - "Dantrolene infusion may relieve muscle rigidity but does not reverse the other manifestations of GABAergic agonist withdrawal. "
12/16/1996 - "In addition to the similarity of the signs and symptoms, all parameters measured (muscle rigidity, body temperature, and serum CPK level) were normalized by dantrolene treatment. "
01/01/1993 - "It is postulated that the severe muscle rigidity may have precluded the circulation of dantrolene to its site of action. "
|5.||Haloperidol (Haldol)FDA LinkGeneric
09/01/2005 - "decreased the haloperidol-induced muscle rigidity measured as an increased muscle resistance of the rat's hind leg in response to passive extension and flexion at the ankle joint. "
09/20/2002 - "AIDA in doses of 7.5-15 microg/0.5 microl diminished the haloperidol-induced muscle rigidity. "
09/20/2002 - "Haloperidol (1 mg/kg ip) induced parkinsonian-like muscle rigidity, measured as an increased resistance of a rat's hind foot to passive flexion and extension at the ankle joint. "
08/21/2002 - "We measured muscular rigidity with a new method by determining the resistance of the hindlimb to passive flexion in the 'balance test' and also checked haloperidol (3 mg/kg i.p.) treated rats for muscular rigidity. "
06/08/2001 - "(S)-4C3HPG injected in doses of 5 and 15 microg/0.5 microl bilaterally, into the rostral region of the striatum, decreased both the haloperidol-induced muscle rigidity (MMG) and the enhanced electromyographic activity (EMG). "
11/01/1994 - "This study suggests that benzodiazepine pretreatment is frequently, but not always, effective in preventing opioid-induced muscle rigidity."
05/01/1992 - "The response to and tolerance of benzodiazepines are striking in newborns and infants and suggest an aberrant central nervous system reflex as the etiology; therefore, hyperekplexia should be considered in the evaluation of neonates and infants with apnea, aspiration pneumonia, episodic muscular rigidity, hyperexcitability, and near-miss sudden infant death syndrome. "
01/01/1983 - "Reversal of the muscle relaxant effect of diazepam by the specific benzodiazepine antagonist Ro 15-1788: an electromyographic study in morphine model of muscular rigidity in rats."
01/01/1983 - "When the competitive antagonist Ro 15-1788 (ethyl-8-fluoro-5, 6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5a]-[1,4]benzodiazepine-3 -carboxylate) (5 mg/kg i.p.) was administered together with diazepam (5 mg/kg i.p.), it prevented the effect of diazepam, although by itself it did not affect the morphine-induced muscular rigidity. "
|7.||Morphine (MS Contin)FDA LinkGeneric
11/01/2008 - "Morphine was highly efficacious in all the nociceptive models employed, but also elicited a potent inhibition of gastric motility, caused severe muscle rigidity and locomotor disturbances and displayed a potential for abuse liability at the higher doses tested (> or =10 mg/kg morphine). "
10/01/2009 - "It is not clear whether the first occurrence of muscle rigidity was morphine-induced. "
10/01/2009 - "An objective causality assessment using the Naranjo probability scale revealed that the likelihood of morphine causing the patient's muscle rigidity on the second occasion was highly probable to definite. "
10/01/2009 - "The second occasion occurred a few hours later, when the patient received a continuous infusion of morphine 4.4 microg/kg/h in the intensive care unit and experienced generalized muscle rigidity with respiratory compromise. "
10/01/2009 - "Morphine-induced muscle rigidity in a term neonate."
|8.||Levodopa (L Dopa)FDA LinkGeneric
01/01/1978 - "In a prevalent muscular rigidity the functions of the dophaminergic systems should be intensified: on the one hand, by administering precursors of dophamine L-DOPA, on the other--by inhibiting antagonistic activity with the aid of different cholinolytic preparations. "
01/01/2001 - "In contrast, among cases without 4- to 6-Hz tremor and cogwheel rigidity, those with a reduced SNpc width or L-dopa responders were significantly less frequent among cases with SLP (25 and 38%, respectively) than among those without significant infarct (75 and 71%, respectively; p < 0.05). "
01/01/2001 - "Among cases with 4- to 6-Hz tremor and cogwheel rigidity, the frequency of patients with a reduced SNpc width and L-dopa responders did not significantly differ between those with SLP (73 and 83%, respectively) and those without significant infarct (83 and 86%, respectively), suggesting that the diagnosis for most of these cases would be probable IPD. "
11/01/1991 - "The diagnosis of PD was based on the presence of three symptoms (resting tremor, cogwheel rigidity and bradikinesia) which are characteristic of PD, and the effectiveness of L-DOPA therapy. "
05/01/2012 - "Levodopa improved bradykinesia and muscular rigidity, but not the postural tremor."
03/01/2004 - "The mixture induced a significantly longer period of anaesthesia, and either substantially reduced or eliminated the adverse effects associated with ketamine anaesthesia (e.g., excessive salivation, bouts of sneezing, rough recoveries, and muscle rigidity). "
04/18/1981 - "This combination effectively reduced some of the undesirable effects of ketamine, such as muscle rigidity, insufficient suppression of reflexes and tachycardia. "
07/23/1993 - "The present study examined the effect of denervating the coerulospinal noradrenergic pathway on the muscular rigidity elicited by fentanyl in Sprague-Dawley rats anesthetized with ketamine. "
07/01/2000 - "Ketamine (15 mg/kg) under the same conditions less potently prevented the development of oligokinesia, did not prevent the development of muscular rigidity, and did not antagonize glutamate toxicity. "
06/01/1996 - "Doses of midazolam of 0.5 mg/kg or above decreased muscle rigidity but did not affect salivation or respiratory pattern observed in cats which received ketamine alone. "
01/01/2000 - "baclofen appears to be effective in resolving muscle rigidity and in avoiding the need for deep sedation and for tracheal intubation, thus achieving lower mortality. "
06/01/2002 - "To suggest guidelines for the prevention, recognition, and management of a life-threatening syndrome (high fever, altered mental status, profound muscular rigidity that sometimes progressed to fatal rhabdomyolysis) in patients who experience the abrupt withdrawal of intrathecal baclofen (ITB) therapy. "
01/01/2001 - "The painful muscle rigidity and severe spasms suffered by patients with brain and spinal injury can be managed even more successfully than in the past with intrathecal baclofen. "
01/01/2014 - "The objective of the present study was to fabricate and evaluate a multiparticulate oral gastroretentive dosage form of baclofen characterized by a central large cavity (hollow core) promoting unmitigated floatation with practical applications to alleviate the signs and symptoms of spasticity and muscular rigidity. "
01/01/1982 - "5 Other drugs that had little or no detectable effect on the muscle rigidity of the spastic mouse included diphenylhydantoin (30 mg/kg, i.p.) and bromocriptine (10 mg/kg, s.c.) while, in some animals, benztropine (2 mg/kg, i.p.) and baclofen (10 mg/kg, i.p.) increased muscle rigidity. "
07/01/2004 - "We conclude that immobilization of these felids with TH-ZH and KH-XH is effective and safe, but TH-ZH is preferred because of the smaller volume of drug necessary for sedation, faster time to induction, and absence of prolonged muscle rigidity during anesthesia."
11/01/1989 - "Whereas muscular rigidity is a well-known phenomenon that is related to anesthesia induced by large doses of narcotic drugs, the precise underlying mechanism(s) remain to be fully elucidated. "
06/01/2000 - "The presence of these anomalies as well as the potential for muscle rigidity with or without hyperthermia present challenges to anesthesia. "
02/01/2013 - "Malignant hyperthermia susceptibility (MHS) is a potentially lethal disorder, characterized by extreme hypermetabolism and muscle rigidity/rhabdomyolysis during anesthesia with potent inhalational agents, in otherwise healthy individuals. "
05/01/1988 - "We report a family in which two sisters with myotonia congenita (MyC) were referred for malignant hyperthermia (MH) evaluation after each developed muscle rigidity with anesthesia. "
03/01/1992 - "Although sufficient analgesia was obtained up to L1 level after spinal anesthesia, the muscular rigidity remained. "
02/01/1987 - "After subcutaneous injection, the opiates produced dose-dependent analgesia, blocked the pinna and cornea reflexes, and induced muscle rigidity. "
01/01/1982 - "Application of the current at lower frequencies (100 to 2,500 Hz) produced analgesia only, whereas higher current intensities at the same frequencies caused respiratory paralysis and muscular rigidity. "
10/01/2003 - "Maternal satisfaction, quality of analgesia, maternal side effects (sedation, depression, breathing, muscle rigidity, nausea, and vomiting) and fetal side effects (heart rate variability and Apgar score) were evaluated. "
01/01/2004 - "Recovery time, postoperative analgesia evaluated by VAS, cardiocirculatory parameters and side effects like nausea, vomiting, shivering, muscle rigidity, sedation and respiratory depression were recorded. "