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Multiple Myeloma

A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
Also Known As:
Kahler Disease; Myeloma-Multiple; Myelomatosis; Plasma Cell Myeloma; Cell Myeloma, Plasma; Cell Myelomas, Plasma; Disease, Kahler; Multiple Myelomas; Myeloma Multiple; Myeloma, Multiple; Myeloma, Plasma Cell; Myeloma-Multiples; Myelomas, Multiple; Myelomas, Plasma Cell; Myelomas, Plasma-Cell; Myelomatoses; Plasma Cell Myelomas; Plasma-Cell Myeloma; Plasma-Cell Myelomas; Myeloma, Plasma-Cell
Networked: 14060 relevant articles (1172 outcomes, 2130 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Non-Hodgkin Lymphoma (Lymphosarcoma)
3. Neoplasm Metastasis (Metastasis)
4. Breast Neoplasms (Breast Cancer)
5. Lymphoma (Lymphomas)

Experts

1. Anderson, Kenneth C: 345 articles (12/2015 - 01/2002)
2. Richardson, Paul G: 168 articles (01/2016 - 06/2002)
3. Hideshima, Teru: 167 articles (10/2015 - 01/2002)
4. Palumbo, Antonio: 142 articles (01/2016 - 06/2002)
5. Chauhan, Dharminder: 113 articles (04/2014 - 02/2002)
6. Munshi, Nikhil C: 111 articles (10/2015 - 02/2002)
7. Rajkumar, S Vincent: 106 articles (09/2015 - 02/2002)
8. Goldschmidt, Hartmut: 104 articles (11/2015 - 09/2002)
9. Barlogie, Bart: 98 articles (12/2015 - 02/2002)
10. Moreau, Philippe: 93 articles (01/2016 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Multiple Myeloma:
1. bortezomib (Velcade)FDA Link
2. Thalidomide (Thalomid)FDA Link
3. Dexamethasone (Maxidex)FDA LinkGeneric
4. lenalidomide (CC 5013)FDA Link
5. Proteasome Endopeptidase Complex (Proteasome)IBA
6. Melphalan (Alkeran)FDA LinkGeneric
7. Cyclophosphamide (Cytoxan)FDA LinkGeneric
8. Prednisone (Sone)FDA LinkGeneric
9. Doxorubicin (Adriamycin)FDA LinkGeneric
10. Vincristine (Oncovin)FDA LinkGeneric

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Stem Cell Transplantation
3. Transplants (Transplant)
4. Transplantation (Transplant Recipients)
5. Combination Drug Therapy (Combination Chemotherapy)