Mouth Abnormalities

Congenital absence of or defects in structures of the mouth.

Also Known As:

Abnormalities, Mouth; Abnormality, Mouth; Mouth Abnormality

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Spinal Dysraphism (Spina Bifida)
2.	Hypospadias
3.	Cleft Palate (Palate, Cleft)

Drugs and Important Biological Agents (IBA) related to Mouth Abnormalities:

1.	Valproic Acid (Depakote)FDA LinkGeneric 10/01/2013 - "There were statistically significant (P < 0.05) associations between (i) valproate exposure and spina bifida, malformations of the heart and great vessels, digits, skull bones, and brain, but not hypospadias, cleft palate/lip and mouth abnormalities, (ii) topiramate exposure and hypospadias and brain maldevelopments, and (iii) carbamazepine (CBZ) exposure and renal tract abnormalities. "
2.	Carbamazepine (Tegretol)FDA LinkGeneric 10/01/2013 - "There were statistically significant (P < 0.05) associations between (i) valproate exposure and spina bifida, malformations of the heart and great vessels, digits, skull bones, and brain, but not hypospadias, cleft palate/lip and mouth abnormalities, (ii) topiramate exposure and hypospadias and brain maldevelopments, and (iii) carbamazepine (CBZ) exposure and renal tract abnormalities. "
3.	Topiramate (Topamax)FDA LinkGeneric 10/01/2013 - "There were statistically significant (P < 0.05) associations between (i) valproate exposure and spina bifida, malformations of the heart and great vessels, digits, skull bones, and brain, but not hypospadias, cleft palate/lip and mouth abnormalities, (ii) topiramate exposure and hypospadias and brain maldevelopments, and (iii) carbamazepine (CBZ) exposure and renal tract abnormalities. "