Monoamine Oxidase (MAO)
An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.
Also Known As:
MAO; MAO-A; Monoamine Oxidase A; MAO-B; Monoamine Oxidase B; Oxidase, Monoamine; Amine Oxidase (Flavin-Containing); Type A Monoamine Oxidase; Type B Monoamine Oxidase; Tyramine Oxidase; MAO A; MAO B; Oxidase, Tyramine; Amine:oxygen oxidoreductase (deaminating) (flavin-containing)
Networked: 3935
relevant articles (147 outcomes,
588 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Youdim, Moussa B H:
40 articles
(01/2022 - 04/2002)
|
2. | Petzer, Jacobus P:
35 articles
(08/2022 - 01/2009)
|
3. | Mathew, Bijo:
30 articles
(08/2022 - 01/2014)
|
4. | Shih, Jean C:
28 articles
(10/2022 - 05/2004)
|
5. | Petzer, Anél:
28 articles
(01/2022 - 03/2012)
|
6. | Meyer, Jeffrey H:
22 articles
(01/2022 - 12/2009)
|
7. | Amit, Tamar:
22 articles
(01/2016 - 10/2003)
|
8. | Kim, Hoon:
21 articles
(03/2022 - 10/2016)
|
9. | Chen, Kevin:
17 articles
(01/2022 - 05/2004)
|
10. | Weinreb, Orly:
17 articles
(01/2017 - 09/2004)
|
Related Diseases
1. | Parkinson Disease (Parkinson's Disease)
|
2. | Alzheimer Disease (Alzheimer's Disease)
|
3. | Dyskinesias (Dyskinesia)
|
4. | Body Weight (Weight, Body)
11/01/2017
- " Next, body weight gain, behavioral parameters (VCMs and open field tests-locomotor and rearing activity), and MAO activity were evaluated. " 01/01/2013
- " Body weight, waist circumference and total fat mass decreased significantly in response to the intervention in both MAO and MHO women (all p < 0.001). " 03/01/2008
- " After administration, the death rate, body weight, training scores, brain index, MAO-B, SOD, GSH-Px in brain and NO, LDH in serum were determined. " 09/17/2004
- " The MAO A/B KO mice showed reduced body weight compared with wild type mice. " 10/01/1984
- " The monoamine oxidase activity in the cerebral hemispheres decreased significantly after 2, 4, 8 and 16 hr of 6-amino-nicotinamide (35 mg/kg body weight, i.p.) administration. "
|
5. | AIDS-Related Complex (ARC)
|
|
Related Drugs and Biologics
Related Therapies and Procedures