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Molindone (Molindone Hydrochloride)

An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of CLOZAPINE. (From AMA Drug Evaluations Annual, 1994, p283)
Also Known As:
Molindone Hydrochloride; Endo Brand of Molindone Hydrochloride; Moban; Molindone Monohydrochloride; Hydrochloride, Molindone; Monohydrochloride, Molindone; 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-
Networked: 60 relevant articles (4 outcomes, 9 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Findling, Robert L: 5 articles (05/2012 - 08/2007)
2. McClellan, Jon: 4 articles (05/2012 - 08/2007)
3. Lieberman, Jeffrey A: 4 articles (05/2012 - 08/2007)
4. Sikich, Linmarie: 4 articles (05/2012 - 08/2007)
5. Frazier, Jean A: 4 articles (05/2012 - 08/2007)
6. Hamer, Robert M: 4 articles (05/2012 - 08/2007)
7. Vitiello, Benedetto: 4 articles (05/2012 - 08/2007)
8. Maloney, Ann E: 3 articles (06/2010 - 08/2007)
9. Ritz, Louise: 3 articles (06/2010 - 08/2007)
10. Johnson, Jacqueline L: 2 articles (05/2012 - 06/2010)

Related Diseases

1. Schizophrenia (Dementia Praecox)
2. Psychotic Disorders (Schizoaffective Disorder)
3. Neuroleptic Malignant Syndrome
4. Movement Disorders (Movement Disorder)
5. Catalepsy

Related Drugs and Biologics

1. Risperidone (Risperdal Consta)
2. olanzapine (Zyprexa)
3. Haloperidol (Haldol)
4. Clozapine (Clozaril)
5. Lithium
6. Antipsychotic Agents (Antipsychotics)
7. Dopamine (Intropin)
8. Dopamine Receptors (Dopamine Receptor)
9. Benztropine (Benzatropine)
10. Amantadine (Aman)

Related Therapies and Procedures

1. Aftercare (After-Treatment)