|1.||Rizzoli, Paul: 2 articles (02/2014 - 04/2007)|
|2.||Walther, A: 2 articles (09/2013 - 09/2001)|
|3.||Lai, Yih-Loong: 2 articles (11/2009 - 01/2005)|
|4.||Lin, Tai-Yin: 2 articles (11/2009 - 01/2005)|
|5.||Javid, Farideh A: 2 articles (12/2006 - 11/2002)|
|6.||Naylor, Robert J: 2 articles (12/2006 - 11/2002)|
|7.||Branco, Luiz G S: 2 articles (08/2006 - 05/2005)|
|8.||Gargaglioni, Luciane H: 2 articles (08/2006 - 05/2005)|
|9.||Martins, Marco A: 2 articles (06/2006 - 02/2003)|
|10.||e Silva, Patrícia M R: 2 articles (06/2006 - 02/2003)|
06/01/1988 - "Not unexpectedly, the acute administration of methysergide, a drug effective in the prophylactic treatment of headache, was inactive in this acute model. "
09/01/1991 - "[Prophylaxis with methysergide of headache caused by dural puncture (preventive note)]."
11/21/1966 - "Aortic obstruction associated with methysergide maleate therapy for headaches."
02/17/1966 - "Adverse effects of methysergide in headache prophylaxis."
02/17/1966 - "Fibrotic disorders associated with methysergide therapy for headache."
04/01/2005 - "The 5-HT1,2 antagonist methysergide (10 and 100 pmol) enhanced edema, but higher doses ( 4 and 8 nmol) diminished edema. "
02/15/1996 - "To determine the extent to which edema modulation by methysergide is due to a blunting of the regional vasodilator response to scald and/or local reduction of transvascular fluid flux, a canine hind limb lymphatic was cannulated. "
01/01/1995 - "Effects of methysergide administration on edema formation at the site of scald."
09/01/2013 - "Administration of methysergide (Met), a serotoninergic receptor blocking agent, reduces generalized edema in endotoxemia in rats. "
09/01/2013 - "Methysergide attenuates systemic burn edema in rats."
|3.||Migraine Disorders (Migraine)
12/14/1963 - "Methysergide was used as a regular medication to prevent migraine in a series of 87 patients with frequently recurring severe attacks of three types, common, classical and cluster migraine, in a study conducted during a 30-month period. "
08/01/1963 - "CLINICAL AND LABORATORY NOTE EEG STUDY OF METHYSERGIDE IN MIGRAINE."
02/01/2014 - "The development of methysergide as the first migraine preventive agent not only laid the groundwork for our current thinking about migraine prevention, but also created a paradigm shift away from migraine as a psychological issue and toward migraine as a legitimate medical condition. "
11/01/2008 - "We describe the rise, fall and subsequent use as a third-choice drug of the first effective migraine prophylactic, methysergide."
11/01/2008 - "History of methysergide in migraine."
11/01/1976 - "Animals pretreated with methysergide, a known 5-hydroxytryptamine receptor blocking agent, had significantly greater alcohol-induced withdrawal convulsions than saline pretreated controls. "
01/01/2015 - "Furthermore, seizure thresholds were negatively correlated with serotonin levels (correlation coefficient; 0.71, P < 0.01), while intracerebroventricular methysergide lowered the seizure threshold (P < 0.05 vs. saline). "
01/01/2014 - "Pretreatments of the dmPAG or the vlPAG columns with the nonselective serotonergic receptors antagonist methysergide (5.0 µg/0.2 µL) or intramesencephalic microinjections of ketanserin (5.0 µg/0.2 µL), a serotonergic antagonist with more affinity to 5-HT2A/2C receptors, decreased tonic-clonic seizure-induced antinociception. "
08/02/1991 - "These seizures were suppressed by methysergide or benserazide. "
04/04/1983 - "Methysergide or 5-HTP failed to inhibit, but PCPA intensified the convulsion. "
|5.||Cluster Headache (Cluster Headaches)
02/01/1996 - "After unsuccessful treatment directed at potential infectious and inflammatory causes, the patient responded well to methysergide, an established treatment for cluster headaches. "
05/01/2014 - "This case report concerns a woman treated continuously since at least 10 years by methysergide for cluster headache. "
09/20/1991 - "For 5 years he had been taking methysergide for cluster headaches. "
07/01/1986 - "Most patients with the episodic type of cluster headache do well on prophylactic treatment with methysergide. "
01/01/2009 - "It is also an active metabolite of methysergide and previous studies suggest that it could be effective against refractory headache and cluster headache. "
|4.||Serotonin (5 Hydroxytryptamine)
|6.||Pizotyline (BC 105)
|5.||Drug Therapy (Chemotherapy)