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Methysergide (Sansert)

An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.
Also Known As:
Sansert; Alliance Brand of Methysergide Maleate; Deseril; Desril; Désernil-Sandoz; Methysergide Dimaleate; Methysergide Maleate; Novartis Brand of Methysergide Maleate; UML-491; Dimaleate, Methysergide; Désernil Sandoz; Maleate, Methysergide; UML 491; UML491; Dimethylergometrin; Methylmethylergonovine; Ergoline-8-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethyl-, (8beta(S))-
Networked: 578 relevant articles (26 outcomes, 29 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Rizzoli, Paul: 2 articles (02/2014 - 04/2007)
2. Walther, A: 2 articles (09/2013 - 09/2001)
3. Lai, Yih-Loong: 2 articles (11/2009 - 01/2005)
4. Lin, Tai-Yin: 2 articles (11/2009 - 01/2005)
5. Javid, Farideh A: 2 articles (12/2006 - 11/2002)
6. Naylor, Robert J: 2 articles (12/2006 - 11/2002)
7. Branco, Luiz G S: 2 articles (08/2006 - 05/2005)
8. Gargaglioni, Luciane H: 2 articles (08/2006 - 05/2005)
9. Martins, Marco A: 2 articles (06/2006 - 02/2003)
10. e Silva, Patrícia M R: 2 articles (06/2006 - 02/2003)

Related Diseases

1. Headache (Headaches)
2. Edema
3. Migraine Disorders (Migraine)
4. Seizures (Seizure)
5. Cluster Headache (Cluster Headaches)

Related Drugs and Biologics

1. Diphenhydramine (Benadryl)
2. Bradykinin
3. Substance P
4. Serotonin (5 Hydroxytryptamine)
5. Fenclonine (p-Chlorophenylalanine)
6. Pizotyline (BC 105)
7. Cyproheptadine (Periactin)
8. p-Methoxy-N-methylphenethylamine
9. Serotonin Receptors
10. Indomethacin (Indometacin)

Related Therapies and Procedures

1. Analgesia
2. Aftercare (After-Treatment)
3. Vagotomy
4. Injections
5. Drug Therapy (Chemotherapy)