Methylprednisolone Hemisuccinate (A-MethaPred)

Subscribe to Selected New Research on Methylprednisolone Hemisuccinate

231 relevant articles (14 outcomes, 43 trials/studies) found for this Drug

Description: A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.

Also Known As:

A-MethaPred; Methylprednisolone Succinate; 6 alpha-Methylprednisolone Sodium Hemisuccinate; Methylprednisolone Hemisuccinate Monosodium Salt; Methylprednisolone Sodium Hemisuccinate; Methylprednisolone Sodium Succinate; Solu-Medrol; Solumedrol; Urbason-Soluble; Hemisuccinate, Methylprednisolone; Sodium Hemisuccinate, Methylprednisolone; Sodium Succinate, Methylprednisolone; Succinate, Methylprednisolone; UrbasonSoluble; Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-, (6alpha,11beta)-

Relationship Network

Drug Context: Research Results

Polycyclic Compounds: 59

Methylprednisolone: 3807

Methylprednisolone Hemisuccinate: 231

6-methylprednisolone-21-hemisuberate N,N,N'-triethylenediamine amide: 19

ASHAP protocol: 1

BOMES protocol: 1

M-BACOS protocol

methylprednisolone 17-hemisuccinate

MINE-ESHAP protocol

VIM3-ARA C regimen

Experts

1.	Saito, Ryoichi: 1 article (03/2004)
2.	Moroi, Seiji: 1 article (03/2004)
3.	Okuno, Hiroshi: 1 article (03/2004)
4.	Ogawa, Osamu: 1 article (03/2004)
5.	Bass, Cynthia Sales: 1 article (10/2003)
6.	Lell, William A: 1 article (10/2003)
7.	Cerfolio, Robert J: 1 article (10/2003)
8.	Thurber, John S: 1 article (10/2003)
9.	Bryant, Ayesha S: 1 article (10/2003)
10.	Bartolucci, Alfred A: 1 article (10/2003)

Related Diseases

1.	Vomiting 07/01/1985 - "In this study patients receiving Reglan had better protection from vomiting than patients receiving Solu-medrol (P = 0.0564). " 07/01/1985 - "Patients receiving the combination of Reglan and Solu-medrol had better protection from vomiting than patients receiving Reglan alone (P = 0.0332), or patients receiving Solu-medrol alone (P = 0.0010). " 01/01/1995 - "[Efficacy of the granisetron/solumedrol combination in the control of drug-induced acute nausea and vomiting. " 07/01/1985 - "This randomized, double-blind study is a comparison of the efficacy of Solu-medrol vs Reglan, as well as, the combination of Solu-medrol and Reglan in the prevention of cis-platinum-induced nausea and vomiting. " 11/01/1986 - "Methylprednisolone sodium succinate and metoclopramide were compared for their efficacy, tolerance, and safety in the prevention of nausea and vomiting induced by moderately emetogenic chemotherapy in patients with cancer. " Order ALL the reference details at left...
2.	Nausea 01/01/1995 - "[Efficacy of the granisetron/solumedrol combination in the control of drug-induced acute nausea and vomiting. " 07/01/1985 - "This randomized, double-blind study is a comparison of the efficacy of Solu-medrol vs Reglan, as well as, the combination of Solu-medrol and Reglan in the prevention of cis-platinum-induced nausea and vomiting. " 11/01/1986 - "Methylprednisolone sodium succinate and metoclopramide were compared for their efficacy, tolerance, and safety in the prevention of nausea and vomiting induced by moderately emetogenic chemotherapy in patients with cancer. " 11/01/1986 - "Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy." 09/01/1993 - "Zofran caused the fewest number of side-effects, solu-medrol inhibited nausea and vomiting significantly, however it caused many side-effects such as flush on a face, restlessness, incitement and headaches. " Order ALL the reference details at left...
3.	Hypothermia 06/01/1978 - "Topical cardiac hypothermia: the effect of methylprednisolone sodium succinate." 05/01/1976 - "An established experimental model in which this lesion could be consistently produced in calves, was utilized to examine the protective role of hypothermia and/or Solumedrol infusion. " 05/01/1976 - "Solumedrol infusion and systemic hypothermia were not sufficiently effective in protecting the myocardium against 40 minutes of left coronary artery occlusion during total cardiopulmonary bypass. " 02/01/1975 - "22 adult mongrel dogs were divided into 4 groups: 1) controls (fluid balanced after endotoxin injection); 2) steroid only administered (methylprednisolone sodium succinate (30 mg/kg, after endotoxin injection); 3) steroids and assisted circulation (normothermal); and 4) assisted circulation (hypothermia). " 07/01/1976 - "Prednisolone sodium succinate (Solumedrol) has helped to obviate pulmonary damage in hemorrhagic and endotoxic shock and therefore may be effective in preventing pulmonary damage following hypothermia. " Order ALL the reference details at left...
4.	Spinal Cord Injuries (Spinal Cord Injury) 03/01/1995 - "A model simulating acute-compressive spinal cord trauma at the second lumbar spinal cord segment (100 g, 300 seconds) was used to evaluate the efficacy of a vehicle control, methylprednisolone sodium succinate (MPSS), and a 21-aminosteroid compound (U74389G). " 11/01/2009 - "Currently, methylprednisolone sodium succinate (MPSS) is the standard treatment following acute spinal cord injury (SCI) as a consequence of the results obtained from the National Acute Spinal Cord Injury Studies. " 05/01/2009 - "BACKGROUND: The use of methylprednisolone sodium succinate (MPSS) in the treatment of traumatic spinal cord injury was initially reported to enhance recovery in the National Acute Spinal Cord Injury Studies (NASCIS), 1990 and 1997. " 01/01/2008 - "Although the primary outcomes in these trials were laregely negative, a secondary analysis of the North American Spinal Cord Injury Study II demonstrated that when administered within 8 hours of injury, methylprednisolone sodium succinate was associated with modest clinical benefits, which need to be weighed against potential complications. " 01/01/2004 - "RESULTS: The publication of the first National Acute Spinal Cord Injury (NASCIS) trial in 1984 ushered in the era of pharmacological trials of therapies intended to improve neurologic outcome in acute SCI. Subsequent trials of methylprednisolone sodium succinate (MPSS) and GM-1 have added to the evidence basis that informs the current management practices for acute SCI. CONCLUSION: The last 50 years have seen a conceptual shift from the pessimism of the past to a cautious optimism that the meager prognosis for neurologic recovery in acute SCI will yield to the progress of medical science. " Order ALL the reference details at left...
5.	Myocardial Infarction 12/01/1983 - "[Methylprednisolone sodium succinate in acute myocardial infarct]" 01/01/1977 - "The number of deaths were the same in both the groups, myocardial infarction and cardiac arrhythmias were definitely lower in the Solu-Medrol group. " 11/01/1980 - "In a double-blind randomized study, 30 mg/kg of methylprednisolone sodium succinate (MPN) or 15 mg/kg of mannitol placebo (PL) were infused in 28 patients after acute myocardial infarction. " 07/01/1984 - "The effect of methylprednisolone sodium succinate (MP) on release of myosin light chain II (LCII) from the myocardium was studied in experimental myocardial infarction (MI). " 01/01/1978 - "This laboratory and others have shown that methylprednisolone sodium succinate and betahistine hydrochloride can each reduce the size of experimental myocardial infarct in dogs at six hours. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Methylprednisolone
2.	Methylprednisolone Hemisuccinate (A-MethaPred)
3.	Cisplatin (Platino)
4.	Cytarabine (Cytosar-U)
5.	Metoclopramide (Reglan)
6.	Granisetron (Kytril)
7.	Misoprostol (Cytotec)
8.	Methotrexate (Mexate)
9.	Bleomycin (Blenoxane)
10.	prednisolone hemisuccinate

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Cardiopulmonary Bypass (Heart-Lung Bypass)
3.	Transplants (Transplant)
4.	Transplantation (Transplant Recipients)
5.	Ligation

Best Treatments:
Research Summary Report
on Vomiting

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 1290 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>