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Methylhydrazines

Hydrazines substituted by one or more methyl groups in any position.

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrazines: 379
  - Methylhydrazines: 2

Related Diseases

1.	Experimental Melanoma 09/01/1986 - "1-(Arylsulfonyl)-2-[(methoxycarbonyl)sulfenyl]-1-methylhydrazines, with the potential to function as biological methylating agents, were synthesized and evaluated as antineoplastic agents against the L1210 leukemia and the B16 melanoma in mice. "
2.	Leukemia L1210 09/01/1986 - "In contrast to the related class of agents, the N,N'-bis(sulfonyl)hydrazines reported earlier by this laboratory,1 the 1-(arylsulfonyl)-2-[(methoxycarbonyl)sulfenyl]-1-methylhydrazines were found to be inactive against the L1210 leukemia in vivo." 09/01/1986 - "1-(Arylsulfonyl)-2-[(methoxycarbonyl)sulfenyl]-1-methylhydrazines, with the potential to function as biological methylating agents, were synthesized and evaluated as antineoplastic agents against the L1210 leukemia and the B16 melanoma in mice. "
3.	Hodgkin Disease (Hodgkin's Disease) 08/01/1978 - "Fortunately, in the 1950's and 1960's, the development of other effective agents (vinca alkaloids, corticosteroids, and methylhydrazines) in conjunction with the elucidation of the principles of combination chemotherapy led to a marked increase in the antitumor response rate of patients with Hodgkin's disease. "

Related Drugs and Biologics

1.	Vinca Alkaloids
2.	Hydrazines
3.	Antineoplastic Agents (Antineoplastics)
4.	Adrenal Cortex Hormones (Corticosteroids)

Related Therapies and Procedures

1.	Combination Drug Therapy (Combination Chemotherapy)