Methyl n-Butyl Ketone

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20 relevant articles (0 outcomes, 2 trials/studies) found for this Bio-Agent

Description: An industrial solvent which causes nervous system degeneration. MBK is an acronym often used to refer to it.

Also Known As:

2 Hexanone; Hexan 2 one; Ketone, Butylmethyl; Ketone, Methyl n-Butyl; Methyl n Butyl Ketone; n-Butyl Ketone, Methyl; 2-Hexanone; Butylmethyl Ketone; Hexan-2-one

Bio-Agent Context: Research Results

Organic Chemicals: 40

Ketones: 289

Hexanones

Methyl n-Butyl Ketone: 20

methyl isobutyl ketone: 12

4-hydroxymethyl isobutyl ketone: 1

ethyl-n-butyl ketone

Related Diseases

1.	Peripheral Nervous System Diseases (PNS Diseases) 01/01/1991 - "Methyl n-butyl ketone (MBK) was considered rather harmless until an outbreak of peripheral neuropathy occurred in 1973 among workers exposed to MBK" 04/05/1976 - "It has been suggested that the solvent methyl N-butyl ketone (MBK) may cause peripheral neuropathy in humans" 11/15/1974 - "Peripheral neuropathy associated with inhalation of methyl-n-butyl ketone." 07/01/1989 - "2. Peripheral neuropathy is mainly associated with n-hexane and methyl n-butyl ketone" 04/01/1975 - "Because of a number of cases of peripheral neuropathy that occurred in factory workers employed in a fabric-printing plant in 1973, chronic inhalation experiments have been conducted using the printing-ink solvents methyl n-butyl ketone (MBK) and methyl iso-butyl ketone (MIBK)" Get all the results and reference details, order at left...
2.	Poisoning 03/01/1977 - "The spatio-temporal evolution of peripheral giant axonal degeneration has been studied in rats during the development of concurrent peripheral (PNS) and central (CNS) nervous system dying-back disease after chronic intoxication with the neurotoxic hexacarbons n-hexane (CH3CH2CH2CH2CH2CH3), methyl n-butyl ketone (MBK) (CH3COCH2CH2CH2CH3), or 2,5-hexanedione (CH3COCH2CH2CHOCH3), a neurotoxic metabolite of MBK" 08/01/1976 - "Feline nervous system response to chronic intoxication with commercial grades of methyl n-butyl ketone, methyl isobutyl ketone, and methyl ethyl ketone." 01/01/1997 - "In order to study the mechanisms of acute n-hexane intoxication, the effects of n-hexane and its metabolites 2-hexanol, methyl-n-butyl ketone, 2,5-hexanediol and 2,5-hexanedione on the cloned voltage-operated potassium channels Kv1.1, Kv1.4, Kv2.1 and Kv3.4 were investigated with electrophysiological techniques in the expression system of Xenopus oocytes" Get all the results and reference details, order at left...
3.	Polyneuropathies (Polyneuropathy) 10/01/1976 - "Symmetrical polyneuropathy developed in two patients after they had been in contact with acrylamide and methyl n-butyl ketone, respectively" 05/01/1976 - "Toxic polyneuropathy secondary to methyl n-butyl ketone." 04/01/1976 - "Letter: Toxic polyneuropathy due to methyl n-butyl ketone." 04/01/1975 - "Toxic polyneuropathy due to methyl n-butyl ketone" 01/01/1975 - "Methyl N-butyl ketone solvent as a recently recognized cause of polyneuropathy." Get all the results and reference details, order at left...
4.	Syndrome 01/01/1982 - "Metabolism of n-hexane and 2-hexanone to 2,5-hexanedione is a prominent feature which appears to be causally related to the neuropathologic syndrome, and mixed solvent effects have been noted in regard to potentiation of hexacarbon neurotoxicity" Get all the results and reference details, order at left...
5.	Neuroblastoma 11/01/1978 - "Effects of neurotoxic industrial solvents on cultured neuroblastoma cells: methyl n-butyl ketone, n-hexane and derivatives." Get all the results and reference details, order at left...
6 Diseases and 20 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	n-hexane
2.	2-hexanol
3.	2,5-hexanedione
4.	2,5-hexanediol
5.	Potassium Channels (Potassium Channel)
6.	2-octanone
7.	Solvents
8.	methyl isobutyl ketone
9.	Taurolithocholic Acid
10.	Carbon Disulfide
11 Drugs and Important Bio-Agents and 11 more articles analyzed in the Research Interface, order at left...

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