|1.||Mathur, P P: 6 articles (04/2010 - 03/2002)|
|2.||Tajima, Y: 3 articles (07/2013 - 03/2011)|
|3.||Fukuyama, T: 3 articles (07/2013 - 03/2011)|
|4.||Kosaka, T: 3 articles (07/2013 - 03/2011)|
|5.||Saradha, B: 3 articles (04/2010 - 11/2008)|
|6.||Vaithinathan, S: 3 articles (04/2010 - 11/2008)|
|7.||Latchoumycandane, C: 3 articles (12/2002 - 03/2002)|
|8.||Kuo, Chun-Chi: 2 articles (02/2015 - 05/2011)|
|9.||Liang, Wei-Zhe: 2 articles (02/2015 - 05/2011)|
|10.||Chou, Chiang-Ting: 2 articles (02/2015 - 05/2011)|
|1.||Body Weight (Weight, Body)
01/01/2014 - "Therefore, the present study explored whether the organochlorine insecticide Methoxychlor (MXC), with known xenoestrogens properties, administered during the perinatal period (from gestational day 11 to postnatal day 8) to pregnant-lactating females, at an environmentally relevant dose (20 µg/kg (body weight)/day), would also affect learning and memory functions depending on the hippocampus of male and female offspring mice in adulthood. "
04/29/2010 - "Animals were orally administered with a single dose of methoxychlor (50mg/kg body weight) and killed at 0, 3, 6, 12, 24, and 72h post-treatment. "
11/01/2008 - "The experimental rats were exposed to a single dose of methoxychlor (50 mg/kg body weight) orally. "
02/14/2005 - "In F1 females, exposure to methoxychlor produced a decrease in the terminal body weight (1000 ppm) and the percentages of cytotoxic T cells (10, 100 and 1000 ppm). "
12/01/2002 - "Methoxychlor (50, 100, or 200 mg/kg body weight per day) was administered orally for 1, 4, or 7 days. "
01/01/2011 - "Finally, the treatment of PC3 prostate tumor-bearing nude mice with [AuCl(2) (DMDT)] significantly inhibited tumor growth in vivo, causing minimal systemic toxicity. "
12/01/1994 - "Methoxychlor neither caused tumor development nor induced epidermal ODC activity. "
12/01/1994 - "Effects of methoxychlor on skin tumor development."
06/01/1980 - "Neoplasms of the pituitary, adrenals, and mammary gland were also increased in methoxychlor-treated female rats. "
02/19/1979 - "Balb/c strain male mice ingesting DDT and C3H strain male mice receiving methoxychlor or DDT did not have testicular tumors. "
06/15/2011 - "The organochlorine pesticide methoxychlor (MXC) is a known endocrine disruptor that affects adult rodent females by causing reduced fertility, persistent estrus, and ovarian atrophy. "
03/01/2011 - "The organochlorine pesticide methoxychlor (MXC) is an immunosuppressive agent thought to affect thymic atrophy by inducing apoptosis of thymocyte T cells. "
01/01/2008 - "Exposure to the pesticide methoxychlor in rodents is linked to impaired steroid production, ovarian atrophy and reduced fertility. "
10/05/2002 - "Thymic atrophy induced by methoxychlor in rat pups."
11/01/2001 - "Male rats receiving methoxychlor showed mainly atrophy of mammary acinus in the 20 mg/ kg and higher groups, together with decreases in prostate and seminal vesicle weights, and atrophy of epididymis, prostate, seminal vesicle and coagulating gland in the 100 and 500 mg/kg groups. "
|4.||Breast Neoplasms (Breast Cancer)
05/01/2012 - "Treatment with bisphenol A and methoxychlor results in the growth of human breast cancer cells and alteration of the expression of cell cycle-related genes, cyclin D1 and p21, via an estrogen receptor-dependent signaling pathway."
01/01/2006 - "With respect to pesticides, breast cancer was positively associated with pounds of the organochlorines methoxychlor (adjusted incidence rate ratio [IRR] for highest quartile = 1.18; confidence interval [CI] = 1.03-1.35) and toxaphene (IRR = 1.16; CI = 1.01-1.34). "
10/02/2002 - "Five natural, pharmaceutical, or xenobiotic chemicals [17beta-estradiol (E2), ethynylestradiol (EE2), diethystilbestrol (DES), methoxychlor (MXC), nonylphenol (NP)] were tested in two in vitro assays [yeast estrogen screen (YES), MCF-7 breast tumor cell proliferation (E-Screen)], and compared with previously reported results from two in vivo male sheepshead minnow vitellogenin (VTG) production studies. "
11/01/2003 - "A group of planar (estradiol, genistein, and coumestrol) and nonplanar (methoxychlor and its mono- and didemethylated phenolic metabolites) environmental estrogens, which are all full estrogens in MCF-7 breast cancer cell proliferation assays, was shown to segregate discretely into planar and nonplanar groups. "
11/01/2001 - "The effects of simultaneous administration of some binary mixtures of seven natural and synthetic oestrogenic substances (17beta-estradiol, estrone, bisphenol A, butylbenzyl phthalate, endosulfan, methoxychlor and pentachlorophenol) on the cellular proliferation of human breast cancer MCF-7 cells in-vitro (a modified E-screen assay) have been measured. "
07/05/2013 - "Prior oral exposure to environmental immunosuppressive chemicals methoxychlor, parathion, or piperonyl butoxide aggravates allergic airway inflammation in NC/Nga mice."
08/01/2014 - "The objective of the study reported here was to investigate the effects of combinations of three well-known environmental immunotoxic chemicals - methoxychlor (MXC), an organochlorine compound; parathion (PARA), an organophosphate compound; and piperonyl butoxide (PBO), an agricultural insecticide synergist - by using a mouse model of ovalbumin (OVA)-induced allergic airway inflammation. "
11/01/1999 - "There was a significant increase in the percent and severity of inflammation in the lateral prostate (as determined by a myeloperoxidase or neutrophil quantification assay) in the estradiol, tamoxifen, and methoxychlor groups as compared to controls. "
|4.||Parathion (Ethyl Parathion)
|9.||Fura-2 (Fura 2)
|2.||Drug Therapy (Chemotherapy)