HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Methotrexate (Mexate)

An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
Also Known As:
Mexate; Methotrexate Hydrate; Methotrexate Sodium; Methotrexate, (D)-Isomer; Methotrexate, (DL)-Isomer; Methotrexate, Dicesium Salt; Methotrexate, Disodium Salt; Methotrexate, Sodium Salt; Dicesium Salt Methotrexate; Hydrate, Methotrexate; Sodium, Methotrexate; Amethopterin; L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
Networked: 24010 relevant articles (2533 outcomes, 3744 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Takeuchi, Tsutomu: 81 articles (11/2022 - 12/2004)
2. Emery, Paul: 81 articles (01/2022 - 02/2002)
3. Tanaka, Yoshiya: 68 articles (11/2022 - 12/2002)
4. Smolen, Josef S: 53 articles (10/2022 - 10/2004)
5. van der Heijde, Désirée: 51 articles (01/2021 - 01/2003)
6. Fleischmann, Roy: 50 articles (01/2022 - 01/2002)
7. Genovese, Mark C: 48 articles (01/2021 - 06/2002)
8. Weinblatt, Michael E: 46 articles (05/2022 - 03/2002)
9. Yamanaka, Hisashi: 46 articles (04/2022 - 04/2002)
10. Keystone, Edward C: 43 articles (02/2022 - 06/2002)

Related Diseases

1. Rheumatoid Arthritis
2. Neoplasms (Cancer)
3. Psoriasis (Pustulosis Palmaris et Plantaris)
4. Lymphoma (Lymphomas)
5. Arthritis (Polyarthritis)

Related Drugs and Biologics

1. Cyclophosphamide (Cytoxan)
2. Doxorubicin (Adriamycin)
3. Cyclosporine (Ciclosporin)
4. Fluorouracil (Carac)
5. Cisplatin (Platino)
6. Vincristine (Oncovin)
7. Etanercept (Enbrel)
8. Infliximab (Remicade)
9. Adrenal Cortex Hormones (Corticosteroids)
10. Antirheumatic Agents (DMARD)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Radiotherapy
4. Combination Drug Therapy (Combination Chemotherapy)
5. Remission Induction